mTOR inhibitor
Everolimus + Letrozole for Endometrial Cancer
Recruiting1 awardPhase 2
Morristown, New Jersey
This trial will test if a combination of everolimus and letrozole can help control endometrial cancer that has come back or is progressing. The safety of this drug combination will also be studied.
Hydroxychloroquine + Everolimus for Breast Cancer
Recruiting1 awardPhase 2
Philadelphia, Pennsylvania
This trial is testing if giving hydroxychloroquine, elesclomol, or a combination of the two drugs to people who have finished primary therapy for breast cancer and have bone marrow disseminated tumor cells is feasible.
mTOR inhibitor
Everolimus + Letrozole +/- Ribociclib for Endometrial Cancer
Recruiting3 awardsPhase 2
Houston, Texas
This trial is testing a new drug combination for advanced or recurrent endometrial cancer. It targets patients whose cancer has spread or returned. The treatment works by blocking enzymes needed for cancer cell growth and by stopping the cells from dividing or spreading. Anlotinib is a new drug that targets multiple aspects of cancer growth.
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Phase 3 Trials
mTOR inhibitor
Long-Term Safety of Everolimus for Tuberous Sclerosis
Recruiting2 awardsPhase 3
Phoenix, Arizona
This trial is for patients with TSC and refractory seizures who are currently receiving everolimus treatment and are determined to be benefiting from it, in order to evaluate the long-term safety of the treatment.
Immunosuppressant
Tacrolimus + Everolimus vs. Tacrolimus + MMF for Heart Transplant Care
Recruiting4 awardsPhase 3
Birmingham, Alabama
This trial will compare two different treatments for kids who have had a heart transplant, to see which one is better at reducing the risk of problems like coronary artery disease, kidney disease, and rejection of the transplant.
Trials With No Placebo
CDK4/6 Inhibitor
Abemaciclib Combination Therapy for Advanced Breast Cancer
Recruiting1 awardPhase 1
Fayetteville, Arkansas
This trial is testing the safety of abemaciclib when used with other treatments for patients whose breast cancer has spread. Abemaciclib helps to stop cancer cells from growing by blocking certain proteins they need. The study aims to find out if this combination is safe for patients with advanced breast cancer.
mTOR inhibitor
Everolimus + Letrozole + Metformin for Endometrial Cancer
Recruiting1 awardPhase 2
Pensacola, Florida
This trial will test if everolimus, letrozole, and metformin can help control endometrial cancer that has come back or is progressing. Researchers will also study if the combination is safe.
Kinase Inhibitor
Vandetanib + Everolimus for Advanced Cancer
Recruiting1 awardPhase 1
Houston, Texas
This trial is testing the side effects and best dose of two drugs when given together to treat patients with cancer that has spread. The drugs may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.
Kinase Inhibitor
Everolimus + Sorafenib for Thyroid Cancer
Recruiting1 awardPhase 2
Basking Ridge, New Jersey
This trial is testing a combination of two pills, sorafenib and everolimus, to treat thyroid cancer. Sorafenib cuts off the tumor's blood supply, while everolimus blocks a protein that helps cancer cells grow. Everolimus is approved for various cancers, including breast cancer, and has shown promise in combination therapies. The study aims to see if this combination works better than current treatments.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.