Popular Trials
Topoisomerase Inhibitor
Chemo-immunotherapy for Pediatric Brain Cancer
Recruiting1 awardPhase 1
Augusta, Georgia
This trial tests a new treatment combining two drugs, ibrutinib and indoximod, with chemotherapy for young patients whose brain cancer has not responded to other treatments. The goal is to boost the immune system's ability to fight the cancer by blocking proteins that help cancer cells survive.
Popular Filters
Trials for Brain Tumor Patients
Checkpoint Inhibitor
Nivolumab for Brain Cancer
Recruiting1 awardPhase 2
La Jolla, California
This trial will test whether the immunotherapy drug nivolumab is an effective treatment for people with rare CNS tumors by measuring the shrinkage of tumors or the amount of time it takes for the tumors to grow or spread.
Device
Optune Device for Brain Cancer
Recruiting1 awardPhase 1
Orlando, Florida
This trial tests if a device using electric fields, combined with two drugs, can help children with aggressive brain tumors that have returned after treatment. The device stops cancer cells from growing, while the drugs damage the cancer cells and cut off their blood supply. This approach has been tested for many years and is used for various types of cancer, combining electric pulses with chemotherapy drugs to increase their effectiveness.
Trials for Diffuse Intrinsic Pontine Glioma Patients
Device
Optune Device for Brain Cancer
Recruiting1 awardPhase 1
Orlando, Florida
This trial tests if a device using electric fields, combined with two drugs, can help children with aggressive brain tumors that have returned after treatment. The device stops cancer cells from growing, while the drugs damage the cancer cells and cut off their blood supply. This approach has been tested for many years and is used for various types of cancer, combining electric pulses with chemotherapy drugs to increase their effectiveness.
Alkylating agents
Maintenance Chemotherapy vs Observation for Ependymoma
Recruiting2 awardsPhase 3
Birmingham, Alabama
This trial is studying how well maintenance chemotherapy works compared to observation following induction chemotherapy and radiation therapy in treating young patients with newly diagnosed ependymoma.
Cancer Vaccine
SurVaxM Vaccine for Brain Cancer
Recruiting1 awardPhase 1
Buffalo, New York
This trial tests the SurVaxM vaccine, which helps the immune system target and destroy cancer cells, in children and young adults with certain difficult-to-treat brain cancers. The vaccine works by teaching the immune system to recognize a protein found in cancer cells. Additional substances are used to make the immune response stronger.
Trials With No Placebo
Checkpoint Inhibitor
Nivolumab for Brain Cancer
Recruiting1 awardPhase 2
La Jolla, California
This trial will test whether the immunotherapy drug nivolumab is an effective treatment for people with rare CNS tumors by measuring the shrinkage of tumors or the amount of time it takes for the tumors to grow or spread.
Device
Optune Device for Brain Cancer
Recruiting1 awardPhase 1
Orlando, Florida
This trial tests if a device using electric fields, combined with two drugs, can help children with aggressive brain tumors that have returned after treatment. The device stops cancer cells from growing, while the drugs damage the cancer cells and cut off their blood supply. This approach has been tested for many years and is used for various types of cancer, combining electric pulses with chemotherapy drugs to increase their effectiveness.
Radiation Therapy
Surgery + Re-Irradiation for Recurrent Ependymoma
Recruiting1 awardPhase 2
Memphis, Tennessee
This trial is for people with ependymoma that has come back after initial treatment. Surgery and re-irradiation with higher than usual doses of radiation will be used to try to treat the tumor. Tumor tissue and blood will be studied to learn more about the tumor and how it responds to treatments.
View More Related Trials
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.