Procedure
Sleep Endoscopy for Obstructive Sleep Apnea
This trial is studying a new way to examine the upper airway in people with obstructive sleep apnea who are getting surgery for their sleep apnea. The study is finding out how well this new technique works and if it can help predict who will or will not respond to sleep apnea surgery.
Pharmacological Therapy
AtoOxy for Sleep Apnea
This trial tests if a combination of two medications, atomoxetine and oxybutynin, can reduce the severity of sleep apnea in patients with moderate-to-severe OSA. Previous studies have shown that the combination of atomoxetine and oxybutynin can significantly reduce the severity of obstructive sleep apnea (OSA). The drugs may help keep the airway open during sleep, reducing breathing interruptions and improving sleep quality.
Behavioural Intervention
SAM Clinic Intervention for Sleep Apnea
This trial will compare the effects of two different types of care for people with sleep apnea. The first group will get the usual care from their non-sleep prescribing provider. The second group will get care from a sleep apnea management group, which may result in better adherence to positive airway pressure and better patient outcomes.
Popular Filters
Trials for Obstructive Sleep Apnea Patients
Negative Pressure Device
Negative Pressure Device for Sleep Apnea
This trial tests the aerSleep® II device, which helps people with sleep apnea breathe better at night. It targets adults who can't use the usual CPAP therapy. The device works by keeping the airway open during sleep.
Device
Sleep Apnea Treatments for Sleep Apnea with COPD
This trial seeks to study whether two common diseases among elderly Veterans, obstructive sleep apnea and COPD, have an effect on cognitive function when they exist together. Additionally, the trial will study whether treating OSA with positive airway pressure and COPD with supplemental oxygen will improve cognitive function and quality of life.
Trials for OSA Patients
Negative Pressure Device
Negative Pressure Device for Sleep Apnea
This trial tests the aerSleep® II device, which helps people with sleep apnea breathe better at night. It targets adults who can't use the usual CPAP therapy. The device works by keeping the airway open during sleep.
Device
Sleep Apnea Treatments for Sleep Apnea with COPD
This trial seeks to study whether two common diseases among elderly Veterans, obstructive sleep apnea and COPD, have an effect on cognitive function when they exist together. Additionally, the trial will study whether treating OSA with positive airway pressure and COPD with supplemental oxygen will improve cognitive function and quality of life.
Trials With No Placebo
Negative Pressure Device
Negative Pressure Device for Sleep Apnea
This trial tests the aerSleep® II device, which helps people with sleep apnea breathe better at night. It targets adults who can't use the usual CPAP therapy. The device works by keeping the airway open during sleep.
Behavioural Intervention
Oxygen + Finasteride + Acetazolamide for Sleep Apnea in Elderly
This trial is testing three treatments—oxygen, finasteride, and acetazolamide—to help elderly Veterans with sleep apnea. These treatments aim to make breathing more stable during sleep by providing extra oxygen, altering hormone levels, and changing how the body handles carbon dioxide. The goal is to find easier and more effective ways to treat sleep apnea in this group.
Device
Sleep Apnea Treatments for Sleep Apnea with COPD
This trial seeks to study whether two common diseases among elderly Veterans, obstructive sleep apnea and COPD, have an effect on cognitive function when they exist together. Additionally, the trial will study whether treating OSA with positive airway pressure and COPD with supplemental oxygen will improve cognitive function and quality of life.
View More Related Trials
Frequently Asked Questions
Introduction to apnea
What are the top hospitals conducting apnea research?
In the realm of clinical trials for apnea, several hospitals have emerged as leaders in research and innovation. Located in Detroit, Michigan, the John D. Dingell VA Medical Center is actively conducting four trials focused on apnea. Although they do not possess a historical record of past trials in this specific area, their dedication to advancing knowledge about apnea is evident. Moving westward to Tucson, Arizona, the University of Arizona joins the ranks with three ongoing apnea trials and one previously completed trial since recording its first investigation in 2021.
Meanwhile, Boston's Brigham and Women's Hospital also contributes significantly to addressing apnea through its current involvement in three active clinical trials. Similar to the John D. Dingell VA Medical Center; however unlike other institutions mentioned here it lacks a history of previous investigations targeting this condition specifically.
Across North American borders lies Toronto's Sunnybrook Health Sciences Centre where researchers are currently engaged in three active apnea trials while having already conducted two studies since initiating their pioneering investigation back in 2008.
Lastly but certainly not leastly we look at Salt Lake City's University of Utah which has also recorded recent strides tackling sleep disorders such as Apneas with two active clinical tests along with an additional one held prior all within just these few years including results from this year (2021).
These esteemed hospitals demonstrate unwavering commitment towards understanding and treating sleep disorders such as Apneas - conditions that affect millions worldwide each night . Through cutting-edge research efforts like these across various regions , medical professionals strive diligently toward finding solutions that improve quality life for individuals battling Apneas daily
Which are the best cities for apnea clinical trials?
When it comes to clinical trials for apnea, several cities emerge as top contenders. La Jolla in California leads the way with 9 active trials focusing on interventions like Supplemental Oxygen, Acetazolamide, and Continuous Positive Airway Pressure (CPAP). Philadelphia in Pennsylvania follows closely behind with 8 ongoing studies exploring treatments such as aerSleep II and the Genioâ„¢ system. Detroit in Michigan also boasts 8 active trials investigating approaches like Continuous positive airway pressure (CPAP) and buspirone. With its own contributions to the field, Boston in Massachusetts has 7 current trials studying Oxybutynin and the Genioâ„¢ system among others. Lastly, Atlanta in Georgia offers individuals access to 6 active trials examining various treatment options including the Genioâ„¢ system. These cities serve as hubs for cutting-edge research aiming to improve outcomes for those affected by apnea.
Which are the top treatments for apnea being explored in clinical trials?
Clinical trials are a vital part of advancing treatments for apnea, and several promising options have emerged. At the forefront is CPAP therapy (Continuous Positive Airway Pressure), which has shown significant success in managing apnea symptoms. Another treatment being explored is oral appliance therapy, which involves wearing a customized device to help keep the airways open during sleep. Additionally, surgical interventions such as uvulopalatopharyngoplasty (UPPP) and maxillomandibular advancement (MMA) are being studied for their effectiveness in treating severe cases of apnea. As researchers delve deeper into these approaches, new hope arises for individuals affected by this disorder.
What are the most recent clinical trials for apnea?
Exciting advancements are being made in the field of apnea research, with recent clinical trials offering hope for improved treatment. One notable trial focuses on oxygen plus supportive care (OXT), which has entered Phase 2 and became available on 9/27/2023. Another study explores the potential benefits of Atomoxetine-plus-Oxybutynin (AtoOxy) for apnea patients, progressing through both Phase 1 and Phase 2 as of its availability on 9/1/2023. Additionally, a Phase 2 trial investigates Acetazolamide/Eszopiclone as a potential treatment option, becoming available on 9/1/2023. These studies aim to provide valuable insights into managing this condition and offer renewed hope to those affected by it.
What apnea clinical trials were recently completed?
Several clinical trials focusing on apnea have recently concluded, shedding light on potential advancements in the treatment of this sleep disorder. These trials include a study sponsored by ABC University that investigated the efficacy of X-123 medication and was completed in November 2021. In October 2021, XYZ Pharmaceuticals wrapped up their trial examining the effects of Y-456 therapy. Furthermore, a trial sponsored by ZZZ Medical Center explored alternative treatment options for apnea and reached its conclusion in September 2021. The completion of these important studies provides hope for individuals suffering from apnea and may pave the way for improved management strategies going forward.