Popular Trials
Alkylating agents
Chemotherapy + Stem Cell Transplant for Breast Cancer
This trial is testing a combination of strong cancer drugs, stem cell replacement, surgery, and radiation in patients with severe stage IIIB breast cancer. The goal is to kill cancer cells, help the body recover, remove the tumor, and eliminate any remaining cancer cells.
Chemotherapy
Chemotherapy +/− Trastuzumab for Breast Cancer
This trial is comparing two different regimens of combination chemotherapy given together with or without trastuzumab to see how well they work in treating patients with stage II or stage III breast cancer.
Popular Filters
Trials for Breast Cancer Patients
Robotic Surgery
Robotic vs. Open Mastectomy for Breast Cancer
This trial compares the safety and effectiveness of a new robotic surgery tool, the da Vinci SP Surgical System, to traditional open surgery for patients undergoing breast surgery that spares the nipple. The robotic system aims to improve precision and recovery. The da Vinci SP Surgical System is one of the latest versions of robotic surgery systems, designed for minimally invasive procedures.
Trials for Ductal Carcinoma Patients
Robotic Surgery
Robotic vs. Open Mastectomy for Breast Cancer
This trial compares the safety and effectiveness of a new robotic surgery tool, the da Vinci SP Surgical System, to traditional open surgery for patients undergoing breast surgery that spares the nipple. The robotic system aims to improve precision and recovery. The da Vinci SP Surgical System is one of the latest versions of robotic surgery systems, designed for minimally invasive procedures.
Trials for ER Positive Patients
Hormone Therapy
Ovarian Suppression + Tamoxifen/Exemestane for Breast Cancer
This trial is testing whether suppressing ovarian function and combining it with either tamoxifen or exemestane is more effective than tamoxifen alone in treating premenopausal women with hormone-responsive breast cancer.
Alkylating agents
Chemotherapy +/− Bevacizumab for Breast Cancer
This trial is testing doxorubicin hydrochloride, cyclophosphamide, and paclitaxel with or without bevacizumab to see how well they work in treating patients with lymph node-positive or high-risk, lymph node-negative breast cancer.
Trials for HER2 Positive Patients
Alkylating agents
Chemotherapy +/− Bevacizumab for Breast Cancer
This trial is testing doxorubicin hydrochloride, cyclophosphamide, and paclitaxel with or without bevacizumab to see how well they work in treating patients with lymph node-positive or high-risk, lymph node-negative breast cancer.
Cancer Vaccine
Cancer Vaccine + Sargramostim for Breast Cancer or alternatively, Cancer Vaccine + Sargramostim for Ovarian Cancer
This trial is testing a new treatment for advanced breast and ovarian cancer. The treatment helps the body's defense system recognize and attack cancer cells, while another component increases the number of defense cells. Researchers aim to find the safest dose and see if it effectively triggers the body's defense system. This type of treatment has shown promise in previous studies for its safety and ability to stimulate the body's defense system.
Phase 3 Trials
Hormone Therapy
Ovarian Suppression + Tamoxifen/Exemestane for Breast Cancer
This trial is testing whether suppressing ovarian function and combining it with either tamoxifen or exemestane is more effective than tamoxifen alone in treating premenopausal women with hormone-responsive breast cancer.
Alkylating agents
Chemotherapy +/− Bevacizumab for Breast Cancer
This trial is testing doxorubicin hydrochloride, cyclophosphamide, and paclitaxel with or without bevacizumab to see how well they work in treating patients with lymph node-positive or high-risk, lymph node-negative breast cancer.
Trials With No Placebo
PRMT5 Inhibitor
TNG462 for Solid Cancers
This trial is testing a new oral drug called TNG462 in patients with advanced or metastatic solid tumors that have an MTAP deletion. The drug works by blocking a protein that helps these cancer cells grow. The goal is to see if TNG462 can stop the cancer from growing and spreading.
Robotic Surgery
Robotic vs. Open Mastectomy for Breast Cancer
This trial compares the safety and effectiveness of a new robotic surgery tool, the da Vinci SP Surgical System, to traditional open surgery for patients undergoing breast surgery that spares the nipple. The robotic system aims to improve precision and recovery. The da Vinci SP Surgical System is one of the latest versions of robotic surgery systems, designed for minimally invasive procedures.
View More Related Trials
Frequently Asked Questions
Introduction to breast
What are the top hospitals conducting breast research?
In the ever-evolving world of medical research, hospitals play a vital role in advancing our understanding and treatment of diseases. When it comes to breast cancer clinical trials, several prestigious institutions are leading the way. Located in Duarte, California, City of Hope Medical Center is currently conducting eight active breast trials. While they may not have an extensive history in this specific area, their commitment to innovative research shines through these ongoing endeavors. A similar trend can be seen at M D Anderson Cancer Center in Houston, where seven active breast trials demonstrate their dedication to finding new approaches for breast cancer patients.
Moving across the country to Boston, we find two renowned hospitals making significant contributions as well. Massachusetts General Hospital and Dana-Farber Cancer Institute both have six active breast trials underway. These institutions are known for their rich history of pioneering medical advancements; while they may not have conducted previous breast cancer trials specifically yet these current initiatives prove their unwavering commitment towards improving patient outcomes.
Last but certainly not least is the Mayo Clinic located in Rochester. With five active breast trials taking place within its walls, the Mayo Clinic showcases its ability to attract top talent and foster groundbreaking research efforts despite having no prior completed studies on record related to this condition just yet.
These hospitals serve as beacons of hope for individuals battling breast cancer, offering access to cutting-edge treatments through participation in clinical trials that could shape future standards of care. By pushing boundaries and collaborating with researchers from around the world, these institutions work tirelessly towards one common goal: conquering breast cancer and providing better lives for those affected by this disease
Which are the best cities for breast clinical trials?
When it comes to breast clinical trials, several cities stand out for their active research and developments. Boston, Massachusetts leads the way with 27 ongoing trials investigating treatments like Palbociclib, Niraparib, and Pembrolizumab. Houston, Texas follows closely behind with 26 active studies exploring therapies such as Dermaprazole 1%, Gemcitabine, and Chemotherapy. New york City also showcases its commitment to breast cancer research with 24 ongoing trials focusing on Abemaciclib, Pembrolizumab combined with SRS, and Aerobic Training interventions. Honolulu in Hawaii boasts 20 active trials examining treatments like Palbociclib, Fludeoxyglucose F-18 imaging agent alongside Quality-of-Life Assessment methods. Lastly, Denver in Colorado presents notable contributions through its dedicated investigations into Radiation Therapy approaches along with Trastuzumab and Palbociclib utilization studies. These cities offer valuable opportunities for individuals seeking participation in breast clinical trials to access cutting-edge treatments that may bring about breakthroughs in care.
Which are the top treatments for breast being explored in clinical trials?
[Breast cancer](https://www.withpower.com/clinical-trials/breast-cancer) clinical trials are paving the way for innovative treatments. Currently, daratumumab is leading the pack with 6 active trials and a total of 134 all-time breast cancer trials since its introduction in 2012. Another promising contender is belantamab mafodotin, which has shown potential through 4 ongoing trials and a history of 26 breast cancer trials since its debut in 2018. Additionally, lenalidomide continues to make strides with involvement in three active breast cancer studies and an impressive record of 280 all-time clinical trials since it was first listed in 2003. These advancements bring renewed hope to patients fighting against this devastating disease.
What are the most recent clinical trials for breast?
Exciting advancements are being made in breast cancer research, with recent clinical trials offering new hope and potential treatment options. One such trial is investigating the use of supportive care (APBI) for patients with breast cancer. This Phase 2 study aims to enhance patient outcomes through improved care strategies. Another promising development is the evaluation of pembrolizumab, a targeted therapy that harnesses the power of the immune system to fight breast cancer. This Phase 2 trial seeks to determine its effectiveness as a treatment option. Additionally, an ongoing Phase 3 trial is examining observational approaches in managing breast cancer, providing valuable insights into optimal patient management strategies. These innovative trials highlight the commitment of researchers and clinicians towards improving outcomes for individuals affected by this disease.
What breast clinical trials were recently completed?
Recently completed clinical trials in the field of breast cancer have advanced our understanding and treatment options for this prevalent disease. Notably, a trial sponsored by the National Cancer Institute investigated the effectiveness of a novel targeted therapy and concluded successfully. Another significant milestone was reached with a trial exploring an innovative immunotherapy approach to combat breast cancer, led by a team from Johns Hopkins University School of Medicine. These recent advancements highlight ongoing efforts to improve outcomes for patients facing breast cancer and provide hope for future treatments.