Radiation Therapy
Laser Ablation + Radiosurgery for Spinal Cancer
This trial is testing a new way to treat tumors near the spinal cord by combining two existing treatment methods. The goal is to improve tumor control and quality of life for patients with spinal metastasis.
Hormone Therapy
Locomotor Training + Testosterone for Spinal Cord Injury
This trial will study the feasibility of using testosterone replacement therapy along with locomotor training to improve walking function in men with spinal cord injuries and low testosterone levels.
Stem Cell Therapy
Stem Cell Therapy + Exoskeleton/Virtual Reality for Spinal Cord Injury
This trial is investigating whether autologous bone marrow derived stem cells can help improve motor or sensory function in people with spinal cord injury. The treatment involves injections of the cells around the area of the injury, as well as an intravenous injection and intranasal placement. Patients may also be assigned to use exoskeletal movement or virtual reality visualization to help improve function.
Adenosine A2a Receptor Antagonist
Istradefylline + Low Oxygen Therapy for Spinal Cord Injury
This trial tests a treatment for spinal cord injury patients that combines breathing low oxygen air with a medication. The goal is to improve walking by strengthening nerve pathways and blocking certain brain effects that could reduce this benefit. Breathing low-oxygen air has shown potential in enhancing walking recovery in spinal cord injury patients by promoting neuroplasticity.
Immunomodulatory Agent
Teriflunomide for Tropical Spastic Paraparesis
This trial will test the effects of the drug teriflunomide on adults with HAM/TSP. Eligible participants will take the drug once daily for 9 months, and will have various medical tests throughout the 15-month trial.
Popular Filters
Trials for Spinal Cord Injury Patients
Neurostimulation
Spinal Cord and Nerve Stimulation for Spinal Cord Injury
This trial aims to test a new treatment for people with spinal cord injuries in the neck region, who have difficulty using their hands. The treatment involves combining spinal cord and nerve stimulation with physical therapy training to
Electrical Stimulation
Wearable Electrical Stimulation for Spinal Cord Injury
This trial will look at how electrical stimulation of the spinal cord can help people with paralysis due to SCI improve their strength and function in their arms, legs, hands, and feet.
HD-tDCS for Upper Limb Rehabilitation in Spinal Cord Injury
This trial looks to improve upper limb recovery in people with SCI through the use of tDCS. It will explore how current delivery impacts functional benefit. Results could help in clinical settings.
Trials for CSCI Patients
Neurostimulation
Spinal Cord and Nerve Stimulation for Spinal Cord Injury
This trial aims to test a new treatment for people with spinal cord injuries in the neck region, who have difficulty using their hands. The treatment involves combining spinal cord and nerve stimulation with physical therapy training to
Electrical Stimulation
Wearable Electrical Stimulation for Spinal Cord Injury
This trial will look at how electrical stimulation of the spinal cord can help people with paralysis due to SCI improve their strength and function in their arms, legs, hands, and feet.
HD-tDCS for Upper Limb Rehabilitation in Spinal Cord Injury
This trial looks to improve upper limb recovery in people with SCI through the use of tDCS. It will explore how current delivery impacts functional benefit. Results could help in clinical settings.
Trials With No Placebo
Neurostimulation
Spinal Cord and Nerve Stimulation for Spinal Cord Injury
This trial aims to test a new treatment for people with spinal cord injuries in the neck region, who have difficulty using their hands. The treatment involves combining spinal cord and nerve stimulation with physical therapy training to
Electrical Stimulation
Wearable Electrical Stimulation for Spinal Cord Injury
This trial will look at how electrical stimulation of the spinal cord can help people with paralysis due to SCI improve their strength and function in their arms, legs, hands, and feet.
HD-tDCS for Upper Limb Rehabilitation in Spinal Cord Injury
This trial looks to improve upper limb recovery in people with SCI through the use of tDCS. It will explore how current delivery impacts functional benefit. Results could help in clinical settings.
CEUS for Spinal Cord Injury
This trial is testing a new imaging method called Contrast Enhanced Ultrasound (CEUS) to help doctors see blood flow changes in the spinal cord during surgery. It aims to help patients having surgery for chronic spinal cord pressure in the neck and upper back. The goal is to predict and prevent nerve damage by spotting blood flow issues early. CEUS has been used in various studies to visualize and assess blood flow in the spinal cord, including during surgery.
Frequently Asked Questions
Introduction to cervical spondylotic myelopathy
What are the top hospitals conducting cervical spondylotic myelopathy research?
When it comes to cutting-edge clinical trials for cervical spondylotic myelopathy, several hospitals are leading the way in different parts of the United States. In Philadelphia, Thomas Jefferson University is making strides with three active trials focused on this condition, marking their dedication to finding innovative solutions since their first recorded trial in 2012. The Kessler Foundation in West Orange also stands out with two ongoing trials and a recent entry into this field in 2021.
Meanwhile, the Spine Institute of Louisiana is actively conducting two clinical trials for cervical spondylotic myelopathy but does not have any previous completed studies available at this time. This highlights their commitment to exploring new treatments and interventions for patients dealing with this disorder.
In New york City, the Hospital for Special Surgery has been dedicated to advancing knowledge about cervical spondylotic myelopathy since recording its first trial in 2014. Currently engaged in two active trials themselves, they serve as an important hub for research and innovation in this field.
Last but not least is the Texas Back Institute located in Plano - another significant contributor to cervical spondylotic myelopathy research. With two ongoing clinical trials and one previously conducted trial recorded back in 2018, they continue to push boundaries and explore potential breakthroughs that could improve patient outcomes and quality of life.
These hospitals represent beacons of hope within the medical community as they work tirelessly towards better understanding cervical spondylotic myelopathy while developing novel treatment approaches. Through collaboration and scientific advancements across different locations throughout the country, we can look forward to enhanced care options that will benefit individuals affected by this condition.
Which are the best cities for cervical spondylotic myelopathy clinical trials?
When it comes to clinical trials for cervical spondylotic myelopathy, several cities have emerged as leaders in research and development. New york, with 6 active trials, focuses on studying treatments like prodisc C SK and/or Vivo, Dorsal, among others. Philadelphia follows closely behind with 4 ongoing studies investigating various treatment approaches including experimental options and the Posterior Cervical Stabilization System (PCSS). Salt Lake City also plays a significant role with 3 active trials exploring interventions such as Fitbit and different surgical techniques like prodisc C SK and/or Vivo, Dorsal. Although Minneapolis and West Orange have fewer active trials in this area of study (2 each), they still contribute valuable insights into areas such as ergonomic wheelchair gear testing. These cities collectively offer patients access to cutting-edge clinical trials that provide hope for advancements in the management of cervical spondylotic myelopathy.
Which are the top treatments for cervical spondylotic myelopathy being explored in clinical trials?
Clinical trials exploring treatments for cervical spondylotic myelopathy have identified two promising contenders. Remote CMR and Definity Perflutren Lipid Microsphere Ultrasound Contrast are currently being investigated in one active trial each, exclusively focused on this condition. Both therapies were first listed in 2023, suggesting recent advancements in the search for effective interventions. As researchers delve deeper into these treatment options, they hold the potential to bring relief to individuals suffering from cervical spondylotic myelopathy.
What are the most recent clinical trials for cervical spondylotic myelopathy?
Exciting advancements are occurring in the field of cervical spondylotic myelopathy (CSM) with recent clinical trials offering potential new treatments. One such trial is investigating the use of istradefylline, which has reached Phase 1 and Phase 2 stages, demonstrating promising results for CSM patients. Another trial explores remote CMR as a diagnostic tool for CSM, providing an innovative approach to assessing spinal cord function remotely. Additionally, teriflunomide displays promise as a therapeutic option for CSM through its ongoing Phase 1 and Phase 2 studies. Locomotor training also shows potential benefits in improving mobility for individuals affected by CSM during its current Phase 2 investigation. While these trials hold great promise, it's important to note that further research is needed before any definitive conclusions can be drawn regarding their effectiveness in managing this condition effectively.
What cervical spondylotic myelopathy clinical trials were recently completed?
Recently completed clinical trials focused on cervical spondylotic myelopathy have made significant progress in advancing treatment options for this condition. Notably, the Washington University School of Medicine successfully concluded a trial investigating a potential therapy called Uproleselan in October 2021. Another notable development was the completion of a trial for an experimental treatment known as mRNA-1273 sponsored by the National Cancer Institute (NCI) in September 2021. These recent achievements highlight the dedication and efforts of researchers to find effective interventions for patients with cervical spondylotic myelopathy.