Smoking Cessation Agent
Varenicline for Tardive Dyskinesia
Recruiting5 awardsPhase 4
Philadelphia, Pennsylvania
To test the feasibility of studying effects of smoking cessation with varenicline on antipsychotic drug-induced neurological side effects, we propose a 12 week pilot study of smoking cessation treatment with varenicline in 10 schizophrenia or schizoaffective disorder patients who are actively smoking and have pre-existing TD while receiving stable doses of antipsychotics. Subjects will be followed after a 2 week baseline period to assess changes in smoking status and neurological symptoms using standardized rating scales. The aim is to examine clinically significant effects on antipsychotic-induced neurological side effects that may warrant further investigation.
Nicotinic Acetylcholine Receptor Partial Agonist
Varenicline + NRT for Smoking Cessation
Recruiting2 awardsPhase 4
Houston, Texas
This trial is comparing varenicline to nicotine replacement therapy to see if varenicline is more effective in helping patients quit smoking. Varenicline is a drug that acts the same way as nicotine in the brain but is not habit-forming.
Behavioural Intervention
Smoking Cessation Treatment for Head & Neck Cancer Patients
Recruiting1 awardPhase < 1
Houston, Texas
This trial is designed to study and compare the effectiveness of two types of counseling for cancer patients who want to quit smoking: Acceptance and Commitment Therapy (ACT) and Motivational and Behavioral Counseling (MBC).
Nicotine Replacement Therapy
Harm Reduction for Smoking in People With HIV
Recruiting1 award1 criteria
Bronx, New York
This trial aims to find new ways to help people with HIV who smoke cigarettes. Traditional methods to help them quit smoking have not been very successful. The trial suggests a different approach called harm reduction, which
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