Mucolytic Agent
Ambroxol for Lewy Body Dementia
This trial tests if Ambroxol, a common mucus-clearing medicine, is safe and effective for treating Lewy Body Dementia (LBD). LBD patients are targeted because current treatments only manage symptoms and do not address the underlying protein buildup in the brain. Ambroxol increases an enzyme that helps break down these harmful proteins, potentially improving brain function.
Kinase Inhibitor
Neflamapimod for Lewy Body Dementia
This trial is testing neflamapimod, a drug that may help improve thinking and memory skills. It targets people with Dementia with Lewy Bodies (DLB), who often struggle with these issues. The drug works by reducing inflammation in the brain.
Alpha-1 Adrenergic Blocker
Terazosin for Lewy Body Dementia
This trial is testing if a medication called terazosin can be tolerated by people with a specific type of dementia called dementia with Lewy bodies. The goal is to see if the medication helps the body make and use energy better, which could help these patients. The results will guide future studies on this and similar medications.
Procedure
Home Sleep Apnea Testing for Cognitive Impairment
This trial is investigating whether home sleep apnea testing is more effective than in-laboratory polysomnography in diagnosing obstructive sleep apnea in patients with vascular cognitive impairment or Alzheimer's disease.
Popular Filters
Trials for Dementia Patients
Diagnostic Test
MIBG Scanning for Lewy Body Disease
This trial uses a special radioactive drug and a heart scan to help identify Lewy Body Disease in people with certain neurological symptoms. The scan checks how well the heart absorbs the drug to find early signs of this brain disorder.
Stem Cell Therapy
Stem Cells + Light Therapy for Alzheimer's Disease and Autism
This trial is testing whether stem cells from patients' own bone marrow can improve cognitive impairment and socialization issues in adults with Alzheimer's or autism. Near-infrared light therapy will also be tested.
Trials for Alzheimer's Disease Patients
Stem Cell Therapy
Stem Cells + Light Therapy for Alzheimer's Disease and Autism
This trial is testing whether stem cells from patients' own bone marrow can improve cognitive impairment and socialization issues in adults with Alzheimer's or autism. Near-infrared light therapy will also be tested.
Behavioral Intervention
Music Therapy for Parkinson's Disease and Lewy Body Dementia
This trial is testing whether music therapy can prevent hospital-acquired delirium in patients with Parkinson's and Dementia with Lewy Bodies during hospitalization.
Trials With No Placebo
Diagnostic Test
MIBG Scanning for Lewy Body Disease
This trial uses a special radioactive drug and a heart scan to help identify Lewy Body Disease in people with certain neurological symptoms. The scan checks how well the heart absorbs the drug to find early signs of this brain disorder.
Stem Cell Therapy
Stem Cells + Light Therapy for Alzheimer's Disease and Autism
This trial is testing whether stem cells from patients' own bone marrow can improve cognitive impairment and socialization issues in adults with Alzheimer's or autism. Near-infrared light therapy will also be tested.
Frequently Asked Questions
Introduction to dementia with lewy bodies
What are the top hospitals conducting dementia with lewy bodies research?
When it comes to advancing research and treatment options for dementia with Lewy bodies, several esteemed hospitals are leading the way. At the Mayo Clinic in Rochester, Minnesota, researchers are currently conducting four active clinical trials focused on this condition. With a total of 10 completed trials since their first recorded study in 2008, the Mayo Clinic is at the forefront of understanding and combating dementia with Lewy bodies.
In Philadelphia, Pennsylvania, the University of Pennsylvania is making significant strides as well. Their team is actively engaged in three ongoing clinical trials for dementia with Lewy bodies and has already conducted six studies since their initial trial in 2016. This institution's dedication to uncovering new approaches showcases their commitment to improving outcomes for patients affected by this complex neurological disorder.
On the West Coast, the University of California, San Francisco stands out as a major contributor to dementia with Lewy bodies research. They currently have three active clinical trials underway and have completed five studies overall since recording their first trial in 2015. The innovative work being done at this renowned institution offers hope for individuals living with this challenging disease.
Meanwhile, at the University of Florida in Gainesville—a rising star in medical research—two active clinical trials are focusing on dementia with Lewy bodies. Although they joined the field more recently than others on this list (starting their first recorded trial just two years ago in 2019), they have already made progress toward improving our understanding of this condition and exploring potential treatments.
Lastly but certainly not leastly MD Stem Cells located within Westport—a relatively smaller-scale facility—is making noteworthy contributions too: engaging in two continuous clinical tests aimed specifically towards treating dementia involving lewy body symptoms which were notably first-ever recorded back only during year2016 itself; an admirable accomplishment nonetheless considering its shorter track record when compared alongside other institutions mentioned above
These top hospitals' commitment to groundbreaking research serves as a beacon of hope for those affected by dementia with Lewy bodies. Through their collective efforts, they are paving the way for improved treatment options and ultimately striving to enhance the quality of life for individuals living with this challenging condition.
Which are the best cities for dementia with lewy bodies clinical trials?
When it comes to clinical trials for dementia with Lewy bodies, several cities have emerged as leaders in research and development. Chicago, Illinois is at the forefront with 8 active trials exploring treatments like Zoledronic acid (ZA), intervention approaches, and Neflamapimod. Rochester, Minnesota closely follows with 7 ongoing studies focused on innovative techniques such as 123I-MIBG scintigraphy and potential therapeutic options like Neflamapimod and Zoledronic acid (ZA). Additionally, Philadelphia, Pennsylvania has 6 active trials investigating treatments including Zoledronic acid (ZA) and CT1812 300 mg. While Boca Raton, Florida and Portland, Oregon each have 5 active trials studying various interventions such as CT1812 300 mg and ATH-1017. These cities offer individuals affected by dementia with Lewy bodies access to cutting-edge clinical trials that hold promise for advancing understanding of the condition and improving patient outcomes.
Which are the top treatments for dementia with lewy bodies being explored in clinical trials?
Clinical trials investigating treatments for dementia with Lewy bodies are making significant strides. Among the top contenders is VOCALE LBD+, a promising treatment currently being explored in one active trial dedicated to this specific condition. Another innovative approach under investigation is 123I-MIBG scintigraphy, also involved in one ongoing clinical trial focused on dementia with Lewy bodies. Additionally, researchers are exploring the potential of Tele-neurohub as a treatment option, which has shown promise and is being studied in its own clinical trial. As these investigations progress, new possibilities for managing and treating dementia with Lewy bodies may soon emerge, shining light on a path towards improved patient outcomes and quality of life.
What are the most recent clinical trials for dementia with lewy bodies?
Recent clinical trials offer hope and potential treatment options for individuals dealing with dementia with Lewy bodies. One such trial focuses on the use of 123I-MIBG scintigraphy, a Phase 4 study aimed at further understanding the role of this imaging technique in diagnosing and monitoring the progression of dementia with Lewy bodies. Additionally, neflamapimod has shown promise in a Phase 2 trial as a potential therapeutic intervention for managing symptoms associated with this condition. Another study involving healthy controls provides valuable insights into disease mechanisms and serves as an important benchmark for comparison purposes. These ongoing efforts to explore treatments like CT1812 300 mg highlight the dedication towards finding solutions that can improve quality of life for those affected by dementia with Lewy bodies.
What dementia with lewy bodies clinical trials were recently completed?
A recent clinical trial investigating treatment options for dementia with Lewy bodies has reached a significant milestone. In February 2021, Eisai Inc. successfully completed a trial evaluating the potential of E2027 therapy in tackling this complex neurodegenerative disorder. These findings provide valuable insights into the development of effective treatments for individuals living with dementia with Lewy bodies and highlight the ongoing efforts to improve their quality of life.