Depression Clinical Trials in Chicago, IL

Depression Clinical Trials in Chicago, IL

View the best 10 depression medical studies in Chicago, Illinois. Access promising new therapies by applying to a Chicago-based Depression clinical trial.

Trials in Chicago, Illinois

Here are the top 10 medical studies for depression in Chicago, Illinois

Image of Northwestern University in Chicago, United States.

My Wellbeing Guide

Behavioral Intervention

Recruiting1 award
This trial will compare the effects of the intervention on depressive symptoms in patients with cancer over time.
Image of University of Illinois at Chicago, Division of Specialized Care for Children in Chicago, United States.

Adapted Coping with Depression-Adolescent +5 More

Behavioural Intervention

Recruiting1 award
This trial is testing a combined mental health treatment and care coordination program for youth with disabilities to see if it helps them cope better with anxiety, depression, and manage their health better. 780 youth in Illinois will be randomly placed in either the combined program or care coordination alone.
Image of University of Illinois at Chicago in Chicago, United States.

Exercise Intervention

Focused Muscle Contraction Therapy

Recruiting1 award5 criteria
This trial will investigate whether the GH Method exercise program can improve the overall sense of wellbeing in U.S. Veterans.
Image of Advanced Research Center /ID# 227073 in Anaheim, United States.

Placebo +1 More

Pharmacotherapy

Recruiting1 awardPhase 3
This trial is testing the safety and effectiveness of Cariprazine for treating depressive episodes in children and teenagers with bipolar I disorder. The goal is to find out if Cariprazine can help young people with this condition. Cariprazine is an atypical antipsychotic recently approved for the treatment of depressive episodes in adults with bipolar I disorder.
Image of Sheppard Pratt Health System in Baltimore, United States.

Psilocybin

Psychedelic

Recruiting1 awardPhase 3
This trial is testing a new medication called COMP360 to help people with severe depression that hasn't improved with other treatments. The study involves adults aged 18 and older. Researchers want to see if a single dose of COMP360 can reduce depression symptoms when given with psychological support.
Image of University of Chicago in Chicago, United States.

Psilocybin

Psychedelic

Recruiting1 awardPhase 2
This trial tests psilocybin, a compound from certain mushrooms, on adults with major depressive disorder and borderline personality disorder. It aims to see if psilocybin can improve mood and reduce symptoms by affecting brain chemicals. Psilocybin has shown promise as a treatment for major depressive disorder and has been designated as a breakthrough therapy by the FDA.
Image of Clinical Research Site in Bellflower, United States.

AXS-05

Behavioural Intervention

Recruiting3 awardsPhase 4
This trial is testing AXS-05, a new medication, to see if it can prevent depression from returning in people who have already improved with it. The study focuses on those with major depressive disorder and aims to maintain their balanced brain chemicals to keep them feeling better. AXS-05 (a combination of dextromethorphan and bupropion) has shown positive results in previous trials for major depressive disorder.
Image of Neurobehavioural Research in Cedarhurst, United States.

NMRA 335140

Behavioural Intervention

Verified
Recruiting1 awardPhase 3
This trial is testing a new medication called NMRA 335140 to see if it can help people with Major Depressive Disorder feel less depressed. The study involves an initial evaluation and a treatment phase where participants will receive either the medication or an inactive substance. The medication likely works by changing brain chemicals that affect mood.
Image of MCB Clinical Research Centers, LLC in Colorado Springs, United States.

Aticaprant

Verified
Recruiting1 awardPhase 3
This trial is testing aticaprant to see if it can help adults with major depressive disorder and anhedonia who haven't responded well to other antidepressants. Aticaprant works by blocking certain receptors in the brain to potentially improve depressive symptoms.
Image of NorthShore University Health System in Evanston, United States.

Brief Behavioral Activation Treatment

Behavioral Intervention

Recruiting1 award1 criteria
This trial is examining whether a brief behavioral activation treatment delivered via telemedicine is as effective as the same treatment delivered in person, and whether the treatment delivered by non-mental health nurses is as effective as when delivered by specialist providers.

Phase 3 Trials

Trials With No Placebo

Frequently Asked Questions

Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.