Down Syndrome Clinical Trials 2024

What are the top hospitals conducting down syndrome research?

In the quest to improve the lives of individuals with Down syndrome, top hospitals across the United States are leading the charge in pioneering clinical trials. Nestled in Los Angeles, Children's Hospital Los Angeles is at the forefront of this endeavor. With four active trials focused on Down syndrome and a total of nine completed studies, their commitment dates back to 1999 when they embarked on their first trial dedicated to this condition. Not far away in Aurora, Colorado, Children's Hospital Colorado is making notable strides as well. Through four ongoing trials and a history of nine previous studies since initiating their inaugural trial in 2007, they continue to contribute greatly to understanding and treating Down syndrome.

The journey towards advancing knowledge about Down syndrome also takes us to Birmingham, Alabama where Children's Hospital of Alabama is actively involved in three current trials. Since undertaking their first trial in 2009, they have conducted a total of six studies focusing on this condition. Meanwhile, at Children's Hospital of Orange County located in Orange California; experts here conduct several experiments simultaneously too administering three ongoing tests while holding seven earlier ones looking into down syndromes beginning from its maiden research case initiated back then since ‘99.

Lastly but not least significant stop along our exploration lands us at the renowned Children's National Medical Center situated within Washington D.C., which has been an integral part combating against Down Syndrome for decades now - having commenced almost more than two decade ago precisely around '99 same year as CHLA; it currently boasts an impressive trio set that actively addresses essential aspects through diagnosis or treatments for those affected by down syndromes- thus contributing significantly towards medical advancement

These esteemed institutions epitomize the dedication and relentless pursuit for improved therapies and understanding surrounding Down syndrome. Each clinical trial conducted represents hope for better outcomes and quality-of-life enhancements for individuals living with this genetic disorder

Which are the best cities for down syndrome clinical trials?

When it comes to down syndrome clinical trials, several cities show promise as hubs for research and innovation. Orlando, Florida; Los Angeles, California; and Chicago, Illinois boast 9 active trials each exploring treatments like Dexamethasone, Cytarabine, AAC Generative Language Intervention in the case of Orlando; Dexamethasone, Cytarabine, Treatment (uproleselan, fludarabine) in the case of Los Angeles; and Cytarabine, Dexamethasone, Exercise in the case of Chicago. Additionally New york City offers 7 active trials focusing on treatments such as Cytarabine and various treatment approaches including uproleselan and fludarabine. Lastly Boston has 6 ongoing trials investigating interventions like Dexamethasone and Psychoeducational Curriculum Group. These cities provide individuals with down syndrome opportunities to participate in cutting-edge clinical studies that could potentially shape future treatment options for this condition.

Which are the top treatments for down syndrome being explored in clinical trials?

The exploration of potential treatments for Down syndrome in clinical trials brings hope to individuals and their families. One notable contender is Sargramostim for Injection, currently undergoing one active trial specifically focused on Down syndrome. This treatment option emerged recently, with its first listing occurring in 2023. While the research is still at an early stage, the presence of ongoing trials provides a glimmer of optimism for future advancements in addressing this complex genetic condition.

What are the most recent clinical trials for down syndrome?

Exciting developments are taking place in the field of Down syndrome research, with recent clinical trials exploring potential treatment options. Oxygen plus supportive care (OXT) has shown promise in Phase 2 trials as a potential intervention for individuals with Down syndrome. Another Phase 2 trial investigated the efficacy of Ato-oxy, aiming to improve outcomes and quality of life for those affected by Down syndrome. Additionally, researchers have explored the use of intravenous immunoglobulin (IVIG), methylphenidate, and Sargramostim for Injection as potential treatments in their respective Phase 2 and Phase 1 trials. These studies offer hope for improved management and support for individuals with Down syndrome moving forward.

What down syndrome clinical trials were recently completed?

Recently completed clinical trials focusing on Down syndrome have made significant strides in advancing our understanding and potential treatments for this genetic condition. Notably, a trial sponsored by the National Institutes of Health (NIH) investigated the effects of memantine hydrochloride on cognitive function in individuals with Down syndrome. Another noteworthy study, conducted by Massachusetts General Hospital and supported by LuMind IDSC Foundation, explored the ability of BPN14770 to improve memory and learning abilities among adults with Down syndrome. These groundbreaking trials offer hope for improved interventions and better quality of life for those affected by Down syndrome.