Popular Trials
Angiotensin Receptor Neprilysin Inhibitor
Entresto + Aprepitant for Heart Failure
Recruiting2 awardsPhase 4
New Haven, Connecticut
This trial is testing whether a drug called Entresto, which is given to people with heart failure, is more effective when taken with or without another drug called Aprepitant.
Angiotensin Receptor-Neprilysin Inhibitor
Sacubitril-Valsartan for Heart Failure in HIV
Recruiting2 awardsPhase 2
Boston, Massachusetts
This trial is testing a medication called sacubitril/valsartan in people with HIV who show early signs of heart changes. The medication aims to block a harmful hormone and increase a protective one to prevent heart problems. The study will see if this treatment can improve heart health in these patients.
Angiotensin Receptor Blocker/Neprilysin Inhibitor
LCZ696 for Heart Failure
Recruiting2 awardsPhase 4
Nashville, Tennessee
This trial is testing the hypothesis that the effects of LCZ696 on blood pressure, natriuresis, and diuresis at initiation are due to the inhibition of neprilysin, which degrades endogenous bradykinin. The study will enroll 80 subjects with stable heart failure who will be given LCZ696 50 mg and either the bradykinin B2 receptor antagonist icatibant or placebo vehicle in random order (double-blind).
Popular Filters
Trials With No Placebo
Angiotensin Receptor-Neprilysin Inhibitor
Sacubitril-Valsartan +1 More for Heart Failure
Recruiting5 awardsPhase 4
Cleveland, Ohio
This trial is testing a new heart medication in patients with a left ventricular assist device (LVAD). The goal is to see if the new drug is better tolerated and more effective than the current standard of care.
Natriuretic Peptide Augmentation
Sacubitril/Valsartan for Metabolic Health in Black Individuals
Recruiting1 awardPhase 2
Birmingham, Alabama
This trial tests if sacubitril/valsartan can improve insulin sensitivity and energy use in Black individuals by increasing heart hormone levels. Black individuals are targeted because they often have lower levels of these hormones, leading to higher risks of diabetes. Valsartan has been studied for its potential to improve insulin sensitivity and β-cell function in various populations, including those with impaired glucose metabolism.
Radiopharmaceutical
Radioactive Agent for Cancer
Recruiting1 awardPhase 1 & 2
Duarte, California
This trial tests a new radioactive treatment for adults with advanced cancers that have a specific marker. The treatment aims to see if it is safe and effective by targeting and killing cancer cells using radiation.
Angiotensin Receptor Blocker/Neprilysin Inhibitor
Combination Blood Pressure Therapy for High Blood Pressure
Recruiting3 awardsPhase 4
Nashville, Tennessee
This trial is testing if a two-drug combination can increase blood flow more than one of the drugs can on its own, and if a third drug can interact with the first two to also increase blood flow.
Angiotensin Receptor Neprilysin Inhibitor
Diuretics vs Afterload Reduction for Congestive Heart Failure
Recruiting3 awardsPhase 4
Huntsville, Alabama
This trial is being done to see which treatment options work best for people with congestive heart failure. They will be looking at different treatments like observing the patients, giving them diuretic medicine, or
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.