Popular Filters
Trials for Bone Cancer Patients
Liquid Biopsy for Bone Cancer
Recruiting1 award15 criteria
Los Angeles, California
This trial is testing a blood test that looks for small pieces of tumor DNA in patients with Ewing sarcoma or osteosarcoma. The goal is to see if this test can help predict if the cancer will return after treatment. A group of patients will participate to help researchers understand how useful this test can be.
Alkylating agent
Lurbinectedin for Ewing Sarcoma
Recruiting1 awardPhase 1 & 2
Philadelphia, Pennsylvania
This trial is testing a medication called lurbinectedin in children and young adults who have already been treated for solid tumors or have a type of cancer called Ewing sarcoma that has come back or didn't respond to other treatments. The medication aims to stop cancer cells from growing and spreading. The study will check if the treatment is safe and effective.
Monoclonal Antibodies
LY2880070 + Gemcitabine for Ewing Sarcoma
Recruiting1 awardPhase 2
New York, New York
This trial is testing whether a new drug, LY2880070, combined with the chemotherapy drug gemcitabine, can effectively treat Ewing sarcoma or Ewing-like sarcoma. These cancers are tough to treat, and the combination aims to stop cancer cells from growing and dividing more effectively than current treatments. Gemcitabine is an active drug in advanced breast cancer both as a single agent and in combination with other chemotherapeutic agents.
Alkylating agent
Onivyde + Talazoparib/Temozolomide for Ewing Sarcoma
Recruiting1 awardPhase 1 & 2
Memphis, Tennessee
This trial is testing 2 combinations of therapy in children and young adults with recurrent or refractory solid tumors. The first part of the trial will determine the highest doses of the medications that can be given safely. The second part of the trial will test to see if the tumors go away in children and young adults with Ewing sarcoma.
Topoisomerase I inhibitors
Trabectedin + Irinotecan for Ewing Sarcoma
Recruiting3 awardsPhase 1 & 2
Los Angeles, California
This trial is testing if trabectedin and irinotecan can treat Ewing's sarcoma that has a EWS-FLI1 mutation. Patients will get an infusion of 18F-FLT and have a PET scan to see if the treatment is working.
Trials for Rhabdomyosarcoma Patients
Alkylating agents
PEN-866 + Chemotherapy for Sarcoma
Recruiting1 awardPhase 1 & 2
Bethesda, Maryland
This trial is studying the combination of 3 drugs to see if it can be used to treat adolescents and young adults with solid tumors, Ewing sarcoma, or rhabdomyosarcoma that returned after or did not respond to standard treatments.
Procedure
DW-MRI for Sarcoma in Young Patients
Recruiting1 award
Memphis, Tennessee
This trial is testing whether a method that doesn't involve radiation (DW-MRI) can be used instead of current methods (CT, nuclear bone scan, PET-CT) to measure how well children with sarcomas are responding to therapy, in order to reduce exposure to harmful effects of ionizing radiation.
Alkylating agent
Onivyde + Talazoparib/Temozolomide for Ewing Sarcoma
Recruiting1 awardPhase 1 & 2
Memphis, Tennessee
This trial is testing 2 combinations of therapy in children and young adults with recurrent or refractory solid tumors. The first part of the trial will determine the highest doses of the medications that can be given safely. The second part of the trial will test to see if the tumors go away in children and young adults with Ewing sarcoma.
Anti-metabolites
nab-Paclitaxel + Gemcitabine for Sarcoma
Recruiting1 awardPhase 2
Birmingham, Alabama
This trial is testing if the combination of nab-paclitaxel and gemcitabine can stop tumors from growing in patients whose cancer has come back or did not respond to previous treatments. The study also checks if this combination is safe and tolerable. Nab-paclitaxel (Abraxane) is an albumin-bound paclitaxel that has shown clinical activity in advanced breast and lung cancer and has been tested in combination with gemcitabine for advanced pancreatic cancer, improving response rates and survival.
Trials With No Placebo
Alkylating Agent
Abemaciclib + Chemotherapy for Sarcoma
Recruiting1 awardPhase 2
Phoenix, Arizona
This trial is testing whether adding a new drug called abemaciclib to standard cancer treatments can help children and young adults with Ewing's sarcoma that has come back or did not respond to previous treatments. Abemaciclib works by blocking proteins that help cancer cells grow, which may slow down or stop the tumor. Participation could last several months or more, depending on individual responses.
Alkylating agents
PEN-866 + Chemotherapy for Sarcoma
Recruiting1 awardPhase 1 & 2
Bethesda, Maryland
This trial is studying the combination of 3 drugs to see if it can be used to treat adolescents and young adults with solid tumors, Ewing sarcoma, or rhabdomyosarcoma that returned after or did not respond to standard treatments.
Procedure
DW-MRI for Sarcoma in Young Patients
Recruiting1 award
Memphis, Tennessee
This trial is testing whether a method that doesn't involve radiation (DW-MRI) can be used instead of current methods (CT, nuclear bone scan, PET-CT) to measure how well children with sarcomas are responding to therapy, in order to reduce exposure to harmful effects of ionizing radiation.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.