Antibiotic
Minocycline + Amiodarone for Atrial Fibrillation
Recruiting1 awardPhase 2
Springfield, Massachusetts
This trial will test whether or not minocycline, a safe and common acne drug, is better at preventing atrial fibrillation than amiodarone, the current standard of care. If minocycline is found to be more effective, it could be incorporated into clinical care for this disease, improving outcomes and reducing costs.
Anticoagulant
Edoxaban for Atrial Fibrillation
Recruiting3 awardsPhase 4
Hamilton, Ontario
This trial is testing if edoxaban, a daily blood-thinning medication, can safely reduce stroke risk in high-risk atrial fibrillation patients who have had previous brain bleeds. The goal is to see if it works better than not using any blood thinners or using simpler treatments. Edoxaban has been shown to be effective in preventing stroke with a lower risk of bleeding.
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Trials for Stroke Patients
Anticoagulant
Anticoagulation for Atrial Fibrillation Post-Ablation
Recruiting3 awardsPhase 4
Calgary, Alberta
This trial is comparing medical approaches for stroke prevention in people who have atrial fibrillation (AF) and have undergone a successful procedure called ablation to eliminate or substantially reduce the arrhythmia.
Blood Collection Device Validation for Patients on Blood Thinners
Recruiting0 awards4 criteria
Berkeley, California
This trial is for a medical device manufacturer to qualify their line of blood collection tubes with the FDA. Participants who are currently on anticoagulants will be compensated for their time and resources.
Anticoagulant
Anticoagulation + Antiplatelet Therapy for Post-Operative Atrial Fibrillation
Recruiting2 awardsPhase 3
Little Rock, Arkansas
This trial is looking at whether adding oral anticoagulation to background antiplatelet therapy is effective and safe in preventing thromboembolic events in patients who develop new-onset atrial fibrillation after isolated coronary artery bypass graft surgery.
Anticoagulant
Blood Thinners for Atrial Fibrillation
Recruiting3 awardsPhase 4
Edmonton, Alberta
This trial is testing whether taking blood-thinning pills can prevent strokes and other heart issues in patients who have temporary irregular heartbeats and are at risk of stroke after surgery. These pills are a recent breakthrough in preventing strokes.
Anticoagulant
Apixaban vs Aspirin for Stroke Prevention in Atrial Fibrillation After Brain Bleed
Recruiting1 awardPhase 3
Birmingham, Alabama
This trial is testing whether apixaban is better than aspirin at preventing strokes or death in patients who have recently had a bleed in the brain and also have atrial fibrillation.
Trials for Ischemic Stroke Patients
Anticoagulant
Anticoagulation for Atrial Fibrillation Post-Ablation
Recruiting3 awardsPhase 4
Calgary, Alberta
This trial is comparing medical approaches for stroke prevention in people who have atrial fibrillation (AF) and have undergone a successful procedure called ablation to eliminate or substantially reduce the arrhythmia.
Anticoagulant
Anticoagulation + Antiplatelet Therapy for Post-Operative Atrial Fibrillation
Recruiting2 awardsPhase 3
Little Rock, Arkansas
This trial is looking at whether adding oral anticoagulation to background antiplatelet therapy is effective and safe in preventing thromboembolic events in patients who develop new-onset atrial fibrillation after isolated coronary artery bypass graft surgery.
Anticoagulant
Blood Thinners for Atrial Fibrillation
Recruiting3 awardsPhase 4
Edmonton, Alberta
This trial is testing whether taking blood-thinning pills can prevent strokes and other heart issues in patients who have temporary irregular heartbeats and are at risk of stroke after surgery. These pills are a recent breakthrough in preventing strokes.
Anticoagulant
Apixaban vs Aspirin for Stroke Prevention in Atrial Fibrillation After Brain Bleed
Recruiting1 awardPhase 3
Birmingham, Alabama
This trial is testing whether apixaban is better than aspirin at preventing strokes or death in patients who have recently had a bleed in the brain and also have atrial fibrillation.
Phase 3 Trials
Anticoagulant
Anticoagulation + Antiplatelet Therapy for Post-Operative Atrial Fibrillation
Recruiting2 awardsPhase 3
Little Rock, Arkansas
This trial is looking at whether adding oral anticoagulation to background antiplatelet therapy is effective and safe in preventing thromboembolic events in patients who develop new-onset atrial fibrillation after isolated coronary artery bypass graft surgery.
Anticoagulant
Apixaban vs Aspirin for Stroke Prevention in Atrial Fibrillation After Brain Bleed
Recruiting1 awardPhase 3
Birmingham, Alabama
This trial is testing whether apixaban is better than aspirin at preventing strokes or death in patients who have recently had a bleed in the brain and also have atrial fibrillation.
Factor Xa Inhibitor
Milvexian vs Apixaban for Atrial Fibrillation
Recruiting1 awardPhase 3
Alexander City, Alabama
This trial is testing a new medication called milvexian to see if it can prevent strokes and blood clots as well as an existing drug, apixaban. Apixaban (Eliquis™) was developed by Bristol-Myers Squibb and Pfizer and has been approved for the prevention of stroke in patients with certain heart conditions. The study focuses on patients who are at risk of these serious conditions. Milvexian works by helping to keep the blood flowing smoothly, reducing the chances of dangerous clots forming.
Abelacimab for Atrial Fibrillation
Recruiting1 awardPhase 3
Johns Creek, Georgia
This trial is testing abelacimab, a medication aimed at preventing strokes and blood clots in people with Atrial Fibrillation. These patients are either unsuitable for or have chosen not to use common medications for thinning blood. Abelacimab works by reducing the blood's ability to form dangerous clots.
Trials With No Placebo
Behavioural Intervention
Exercise Training for Atrial Fibrillation
Recruiting1 award5 criteria
Ottawa, Ontario
This trial will compare the effects of high-intensity interval training vs. moderate-intensity continuous exercise training in adults with persistent or permanent atrial fibrillation on exercise capacity and quality of life.
Anticoagulant
Anticoagulation for Atrial Fibrillation Post-Ablation
Recruiting3 awardsPhase 4
Calgary, Alberta
This trial is comparing medical approaches for stroke prevention in people who have atrial fibrillation (AF) and have undergone a successful procedure called ablation to eliminate or substantially reduce the arrhythmia.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.