Mucolytic Agent
Ambroxol for Lewy Body Dementia
Recruiting1 awardPhase 1 & 2
London, Ontario
This trial tests if Ambroxol, a common mucus-clearing medicine, is safe and effective for treating Lewy Body Dementia (LBD). LBD patients are targeted because current treatments only manage symptoms and do not address the underlying protein buildup in the brain. Ambroxol increases an enzyme that helps break down these harmful proteins, potentially improving brain function.
Kinase Inhibitor
Neflamapimod for Lewy Body Dementia
Recruiting0 awardsPhase 2
Lake Worth, Florida
This trial is testing neflamapimod, a drug that may help improve thinking and memory skills. It targets people with Dementia with Lewy Bodies (DLB), who often struggle with these issues. The drug works by reducing inflammation in the brain.
Alpha-1 Adrenergic Blocker
Terazosin for Lewy Body Dementia
Recruiting2 awardsPhase 1 & 2
Iowa City, Iowa
This trial is testing if a medication called terazosin can be tolerated by people with a specific type of dementia called dementia with Lewy bodies. The goal is to see if the medication helps the body make and use energy better, which could help these patients. The results will guide future studies on this and similar medications.
Procedure
Home Sleep Apnea Testing for Cognitive Impairment
Recruiting1 award4 criteria
Toronto, Ontario
This trial is investigating whether home sleep apnea testing is more effective than in-laboratory polysomnography in diagnosing obstructive sleep apnea in patients with vascular cognitive impairment or Alzheimer's disease.
Popular Filters
Trials for Dementia Patients
Diagnostic Test
MIBG Scanning for Lewy Body Disease
Recruiting3 awardsPhase 4
Rochester, Minnesota
This trial uses a special radioactive drug and a heart scan to help identify Lewy Body Disease in people with certain neurological symptoms. The scan checks how well the heart absorbs the drug to find early signs of this brain disorder.
Stem Cell Therapy
Stem Cells + Light Therapy for Alzheimer's Disease and Autism
Recruiting1 award5 criteria
Westport, Connecticut
This trial is testing whether stem cells from patients' own bone marrow can improve cognitive impairment and socialization issues in adults with Alzheimer's or autism. Near-infrared light therapy will also be tested.
Behavioral Intervention
Music Therapy for Parkinson's Disease and Lewy Body Dementia
Recruiting0 awards2 criteria
Worcester, Massachusetts
This trial is testing whether music therapy can prevent hospital-acquired delirium in patients with Parkinson's and Dementia with Lewy Bodies during hospitalization.
Trials for PD Patients
Diagnostic Test
MIBG Scanning for Lewy Body Disease
Recruiting3 awardsPhase 4
Rochester, Minnesota
This trial uses a special radioactive drug and a heart scan to help identify Lewy Body Disease in people with certain neurological symptoms. The scan checks how well the heart absorbs the drug to find early signs of this brain disorder.
Bisphosphonate
Zoledronic Acid for Parkinson's Disease
Recruiting2 awardsPhase 4
Scottsdale, Arizona
This trial is testing whether a single infusion of zoledronic acid can help prevent fractures in people with Parkinson's disease or parkinsonism. A total of 3500 participants will be enrolled in the United States.
Trials With No Placebo
Diagnostic Test
MIBG Scanning for Lewy Body Disease
Recruiting3 awardsPhase 4
Rochester, Minnesota
This trial uses a special radioactive drug and a heart scan to help identify Lewy Body Disease in people with certain neurological symptoms. The scan checks how well the heart absorbs the drug to find early signs of this brain disorder.
Stem Cell Therapy
Stem Cells + Light Therapy for Alzheimer's Disease and Autism
Recruiting1 award5 criteria
Westport, Connecticut
This trial is testing whether stem cells from patients' own bone marrow can improve cognitive impairment and socialization issues in adults with Alzheimer's or autism. Near-infrared light therapy will also be tested.
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.