Leiomyosarcoma Clinical Trials in Philadelphia, PA

Leiomyosarcoma Clinical Trials in Philadelphia, PA

View the best 10 leiomyosarcoma medical studies in Philadelphia, Pennsylvania. Access promising new therapies by applying to a Philadelphia-based Leiomyosarcoma clinical trial.

Trials in Philadelphia, Pennsylvania

Here are the top 10 medical studies for leiomyosarcoma in Philadelphia, Pennsylvania

Image of Sarcoma Oncology Center in Los Angeles, United States.

Lurbinectedin +1 More

Chemotherapy

Recruiting1 awardPhase 2 & 3
This trial will test if a combo of two chemo drugs can prolong progression-free survival in those with metastatic leiomyosarcoma.
Image of The Ottawa Hospital - General Campus in Ottawa, Canada.

Surgery

Recruiting2 awardsPhase 3
This trialtests if chemo before surgery can help people with a certain type of cancer live longer.
Image of Dana-Farber Cancer Institute in Boston, United States.

Everolimus +1 More

mTOR Inhibitor

Recruiting1 awardPhase 2
This trial tests a combination of two drugs, Ribociclib and Everolimus, in patients with advanced DDL and LMS who have not responded to previous treatments. Ribociclib blocks proteins that help cancer grow, while Everolimus stops cancer cells from multiplying. Everolimus is an oral mTOR inhibitor that is approved for various cancers, including renal cell carcinoma and breast cancer.
Image of Women's Cancer Center of Nevada in Las Vegas, United States.

Letrozole

Aromatase Inhibitor

Recruiting1 awardPhase 2
This trial is testing a drug called letrozole in patients with a type of cancer called uterine leiomyosarcoma. The goal is to see if letrozole can help patients live
Image of Children's Hospital of Alabama in Birmingham, United States.

Doxorubicin +2 More

Anthracyclines

Recruiting1 awardPhase 2 & 3
This trial is testing whether a new drug called pazopanib, when combined with chemotherapy and radiation, works better for patients with a specific type of soft tissue cancer. Pazopanib helps stop cancer cells from growing, while chemotherapy and radiation kill the cells. The goal is to see if this combination can improve treatment outcomes.
Image of Mayo Clinic Hospital in Phoenix, United States.

Doxorubicin

Anti-tumor antibiotic

Recruiting1 awardPhase 2
This trial is testing whether adding a new drug to standard treatment can help people with leiomyosarcoma that has spread to other parts of the body.
Image of University of Alabama at Birmingham Cancer Center in Birmingham, United States.

Temozolomide +1 More

Alkylating agents

Recruiting1 awardPhase 2 & 3
This trial is comparing the effectiveness of a combination treatment using olaparib and temozolomide to the common chemotherapy drugs trabectedin or pazopanib. The trial is for patients
Image of National Cancer Institute Developmental Therapeutics Clinic in Bethesda, United States.

Ipilimumab, Nivolumab

Checkpoint Inhibitor

Recruiting1 awardPhase 2
This trial tests 2 combinations of drugs to fight advanced soft tissue sarcoma: immunotherapy and chemotherapy.
Image of Mayo Clinic Hospital in Arizona in Phoenix, United States.

Radiation Therapy +1 More

Radiation

Recruiting1 awardPhase 2
This trial is studying the side effects of talimogene laherparepvec and radiation therapy in treating patients with newly diagnosed soft tissue sarcoma.
Image of Massachusetts General Hospital in Boston, United States.

Lurbinectedin +1 More

Chemotherapy

Recruiting1 awardPhase 1 & 2
This trial is testing a new drug, lurbinectedin, combined with an existing chemotherapy drug, doxorubicin, in patients with advanced leiomyosarcoma. The goal is to see if this combination is safe and more effective than doxorubicin alone. Both drugs work by damaging the DNA in cancer cells, leading to their death. Lurbinectedin is a synthetic marine-derived anticancer agent that has shown promise in treating certain types of cancer.

Phase 3 Trials

Trials With No Placebo

View More Related Trials

Frequently Asked Questions

Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.