Trials in Los Angeles, California
Here are the top 10 medical studies for lung cancer in Los Angeles, California
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Phase 3 Trials
Monoclonal Antibodies
Dato-DXd + Pembrolizumab for Advanced Lung Cancer
Recruiting2 awardsPhase 3
Los Angeles, California
This trial will compare the effectiveness of a new cancer drug, datopotamab deruxtecan, when used with pembrolizumab versus pembrolizumab alone in patients with advanced lung cancer.
Monoclonal Antibodies
Serplulimab + Chemotherapy for Small Cell Lung Cancer
Recruiting3 awardsPhase 3
Los Angeles, California
This trial is testing two different treatment combinations for patients with extensive-stage small cell lung cancer who have not received any prior treatment. One group will receive a new drug called Serplulimab along with standard chemotherapy, while the other group will receive an existing drug called Atezolizumab with the same chemotherapy. Both immunotherapy drugs aim to help the immune system fight cancer, and the chemotherapy drugs work by killing cancer cells. Atezolizumab has been shown to improve survival in small-cell lung cancer when combined with chemotherapy, changing the standard first-line therapy.
Taxane
Ceralasertib + Durvalumab for Lung Cancer
Recruiting3 awardsPhase 3
Los Angeles, California
This trial tests a new combination of drugs (ceralasertib and durvalumab) against a standard treatment (docetaxel) in patients with advanced lung cancer who didn't respond to previous treatments. The new combination aims to weaken cancer cells and boost the immune system, while the standard treatment directly kills the cancer cells.
Small Molecule Kinase Inhibitor
Lazertinib + Amivantamab for Non-Small Cell Lung Cancer
Recruiting2 awardsPhase 3
Long Beach, California
This trial is testing a new, easier to use formulation of amivantamab, which has the potential to reduce administration time and improve the patient and physician experience.
Trials With No Placebo
Chemotherapy
Tarlatamab Combo for Small Cell Lung Cancer
Recruiting1 awardPhase 1
Los Angeles, California
This trial is testing a new drug called tarlatamab combined with treatments that help the immune system fight cancer, and sometimes with chemotherapy. It targets cancer patients who need new treatment options. Tarlatamab attacks cancer cells directly, while other treatments boost the immune response or kill cancer cells.
Monoclonal Antibodies
IOV-4001 for Melanoma and Lung Cancer
Recruiting1 awardPhase 1 & 2
Los Angeles, California
This trial is testing IOV-4001, a modified immune cell treatment, in adults with advanced melanoma or lung cancer. The treatment aims to improve the ability of the patient's own immune cells to attack cancer by disabling a gene that helps cancer hide.
CAR T-cell Therapy
NK Cells +/− Atezolizumab for Lung Cancer
Recruiting1 awardPhase 1
Duarte, California
This trial tests a new treatment using modified immune cells from umbilical cord blood to fight advanced lung cancer that didn't respond to previous treatments. Some patients will also receive a drug that boosts the immune system's ability to attack cancer. The goal is to find the best dose and see if the treatment is safe and effective.
CAR T-cell Therapy
LYL797 for Breast and Lung Cancer
Recruiting1 awardPhase 1
Santa Monica, California
This trial is testing a new treatment called LYL797, which uses modified immune cells to target and kill hard-to-treat breast and lung cancer cells. The study aims to find a safe dose and see how well it works in patients whose cancers have not responded to other treatments.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.