Popular Trials
Radiation Therapy
MR-Guided Radiation + Chemotherapy for Pancreatic Cancer
Recruiting1 awardPhase 2
Milwaukee, Wisconsin
This trial is for people with pancreatic cancer who are ineligible for surgery. To be eligible, patients must have received several months of chemotherapy and their tumor must not have progressed on imaging studies.
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Trials for Adenocarcinoma Patients
CAR T-cell Therapy
A2B530 CAR T Therapy for Solid Cancers
Recruiting1 awardPhase 1 & 2
Los Angeles, California
This trial tests A2B530, a treatment using modified immune cells from the patient, in adults with hard-to-treat cancers like colorectal, pancreatic, and lung cancer. The treatment aims to target and kill cancer cells while protecting healthy cells.
Monoclonal Antibodies
SGN-BB228 for Melanoma
Recruiting1 awardPhase 1
Denver, Colorado
This trial is testing a new drug called SGN-BB228 to see if it can help treat difficult-to-treat cancers like melanoma and other solid tumors. The study will determine the safest amount of the drug to give and check if it works in shrinking or eliminating these tumors. The goal is to find a new treatment option for patients whose cancers are not responding to current therapies.
MDM2 Inhibitor
Brigimadlin for Solid Cancers
Recruiting1 awardPhase 2
Washington, District of Columbia
This trial is testing a medicine called BI 907828 for adults with advanced cancer in the biliary tract, pancreas, lung, or bladder who have no other treatment options. The medicine is taken as a tablet periodically and works by blocking a protein that helps cancer cells grow.
CAR T-cell Therapy
TC-510 Cell Therapy for Cancer
Recruiting1 awardPhase 1 & 2
Nashville, Tennessee
This trial tests TC-510, a therapy using a patient's own modified T cells to target and attack cancer cells. It is aimed at patients with cancers that are hard to treat with standard methods. The modified T cells are designed to recognize specific proteins on cancer cells and get an extra boost to kill them.
Small Molecule Inhibitor
LY3537982 for Cancer
Recruiting1 awardPhase 1 & 2
Indianapolis, Indiana
This trial is testing a new drug called LY3537982 in cancer patients with the KRAS G12C mutation. It targets this mutation to stop cancer cells from growing. The study includes patients who haven't responded to other treatments or cannot tolerate them. LY3537982 is a new drug targeting the KRAS G12C mutation, similar to previously approved drugs like sotorasib and adagrasib.
Trials for Pancreatic Endocrine Carcinoma Patients
CAR T-cell Therapy
A2B530 CAR T Therapy for Solid Cancers
Recruiting1 awardPhase 1 & 2
Los Angeles, California
This trial tests A2B530, a treatment using modified immune cells from the patient, in adults with hard-to-treat cancers like colorectal, pancreatic, and lung cancer. The treatment aims to target and kill cancer cells while protecting healthy cells.
Monoclonal Antibodies
SGN-BB228 for Melanoma
Recruiting1 awardPhase 1
Denver, Colorado
This trial is testing a new drug called SGN-BB228 to see if it can help treat difficult-to-treat cancers like melanoma and other solid tumors. The study will determine the safest amount of the drug to give and check if it works in shrinking or eliminating these tumors. The goal is to find a new treatment option for patients whose cancers are not responding to current therapies.
MDM2 Inhibitor
Brigimadlin for Solid Cancers
Recruiting1 awardPhase 2
Washington, District of Columbia
This trial is testing a medicine called BI 907828 for adults with advanced cancer in the biliary tract, pancreas, lung, or bladder who have no other treatment options. The medicine is taken as a tablet periodically and works by blocking a protein that helps cancer cells grow.
CAR T-cell Therapy
TC-510 Cell Therapy for Cancer
Recruiting1 awardPhase 1 & 2
Nashville, Tennessee
This trial tests TC-510, a therapy using a patient's own modified T cells to target and attack cancer cells. It is aimed at patients with cancers that are hard to treat with standard methods. The modified T cells are designed to recognize specific proteins on cancer cells and get an extra boost to kill them.
Small Molecule Inhibitor
LY3537982 for Cancer
Recruiting1 awardPhase 1 & 2
Indianapolis, Indiana
This trial is testing a new drug called LY3537982 in cancer patients with the KRAS G12C mutation. It targets this mutation to stop cancer cells from growing. The study includes patients who haven't responded to other treatments or cannot tolerate them. LY3537982 is a new drug targeting the KRAS G12C mutation, similar to previously approved drugs like sotorasib and adagrasib.
Trials for Metastatic Patients
CAR T-cell Therapy
A2B530 CAR T Therapy for Solid Cancers
Recruiting1 awardPhase 1 & 2
Los Angeles, California
This trial tests A2B530, a treatment using modified immune cells from the patient, in adults with hard-to-treat cancers like colorectal, pancreatic, and lung cancer. The treatment aims to target and kill cancer cells while protecting healthy cells.
Monoclonal Antibodies
SGN-BB228 for Melanoma
Recruiting1 awardPhase 1
Denver, Colorado
This trial is testing a new drug called SGN-BB228 to see if it can help treat difficult-to-treat cancers like melanoma and other solid tumors. The study will determine the safest amount of the drug to give and check if it works in shrinking or eliminating these tumors. The goal is to find a new treatment option for patients whose cancers are not responding to current therapies.
MDM2 Inhibitor
Brigimadlin for Solid Cancers
Recruiting1 awardPhase 2
Washington, District of Columbia
This trial is testing a medicine called BI 907828 for adults with advanced cancer in the biliary tract, pancreas, lung, or bladder who have no other treatment options. The medicine is taken as a tablet periodically and works by blocking a protein that helps cancer cells grow.
CAR T-cell Therapy
TC-510 Cell Therapy for Cancer
Recruiting1 awardPhase 1 & 2
Nashville, Tennessee
This trial tests TC-510, a therapy using a patient's own modified T cells to target and attack cancer cells. It is aimed at patients with cancers that are hard to treat with standard methods. The modified T cells are designed to recognize specific proteins on cancer cells and get an extra boost to kill them.
Small Molecule Inhibitor
LY3537982 for Cancer
Recruiting1 awardPhase 1 & 2
Indianapolis, Indiana
This trial is testing a new drug called LY3537982 in cancer patients with the KRAS G12C mutation. It targets this mutation to stop cancer cells from growing. The study includes patients who haven't responded to other treatments or cannot tolerate them. LY3537982 is a new drug targeting the KRAS G12C mutation, similar to previously approved drugs like sotorasib and adagrasib.
Trials for BRCA1 Positive Patients
Alkylating agent
Gemcitabine + Cisplatin +/- Veliparib for Pancreatic Cancer
Recruiting1 awardPhase 2
Chicago, Illinois
This trial is studying veliparib in combination with gemcitabine hydrochloride and cisplatin to see how well it works compared to gemcitabine hydrochloride and cisplatin alone in treating patients with pancreatic cancer.
Chemotherapy
Chemotherapy + Stem Cell Transplant for Pancreatic Cancer
Recruiting1 awardPhase 1
New York, New York
This trial is testing a new treatment for pancreatic cancer in patients with an inherited BRCA1 or BRCA2 mutation. The treatment involves a combination of drugs given through an IV, with the goal of determining if it is safe.
PD-1 Inhibitor
Niraparib + Dostarlimab for Cancer
Recruiting1 awardPhase 1
Seattle, Washington
This trial is testing the combination of two drugs to treat patients with BRCA-mutated cancer. Niraparib is an inhibitor of PARP, an enzyme that helps repair DNA. TSR-042 is an immunotherapy that may help the body's immune system attack the cancer.
PARP Inhibitor
Pembrolizumab + Olaparib for Pancreatic Cancer
Recruiting1 awardPhase 2
Fairbanks, Alaska
This trial is testing whether adding pembrolizumab to olaparib, which is the standard of care, is more effective in treating patients with metastatic pancreatic cancer who have BRCA1 or BRCA2 mutations.
Trials for BRCA2 Positive Patients
Alkylating agent
Gemcitabine + Cisplatin +/- Veliparib for Pancreatic Cancer
Recruiting1 awardPhase 2
Chicago, Illinois
This trial is studying veliparib in combination with gemcitabine hydrochloride and cisplatin to see how well it works compared to gemcitabine hydrochloride and cisplatin alone in treating patients with pancreatic cancer.
Chemotherapy
Chemotherapy + Stem Cell Transplant for Pancreatic Cancer
Recruiting1 awardPhase 1
New York, New York
This trial is testing a new treatment for pancreatic cancer in patients with an inherited BRCA1 or BRCA2 mutation. The treatment involves a combination of drugs given through an IV, with the goal of determining if it is safe.
PD-1 Inhibitor
Niraparib + Dostarlimab for Cancer
Recruiting1 awardPhase 1
Seattle, Washington
This trial is testing the combination of two drugs to treat patients with BRCA-mutated cancer. Niraparib is an inhibitor of PARP, an enzyme that helps repair DNA. TSR-042 is an immunotherapy that may help the body's immune system attack the cancer.
PARP Inhibitor
Pembrolizumab + Olaparib for Pancreatic Cancer
Recruiting1 awardPhase 2
Fairbanks, Alaska
This trial is testing whether adding pembrolizumab to olaparib, which is the standard of care, is more effective in treating patients with metastatic pancreatic cancer who have BRCA1 or BRCA2 mutations.
Phase 3 Trials
Anti-metabolites
Chemotherapy for Pancreatic Cancer
Recruiting2 awardsPhase 3
Mobile, Alabama
This trial is studying gemcitabine hydrochloride given with or without erlotinib hydrochloride, followed by the same chemotherapy regimen with or without radiation therapy and capecitabine or fluorouracil, to see how well it works in treating patients with pancreatic cancer that has been removed by surgery.
Tyrosine Kinase Inhibitor
Cabozantinib for Pancreatic Neuroendocrine Tumors
Recruiting1 awardPhase 3
Anchorage, Alaska
This trial compares cabozantinib to placebo in treating neuroendocrine or carcinoid tumors. Cabozantinib is a chemotherapy drug that targets specific tyrosine kinase receptors, which when blocked, may slow tumor growth.
Anti-metabolites
Intra-arterial vs. IV Chemotherapy for Pancreatic Cancer
Recruiting2 awardsPhase 3
Sacramento, California
This trial tests different ways to treat advanced pancreatic cancer that can't be removed by surgery. It uses a combination of chemotherapy drugs and radiation, then compares direct artery chemotherapy to other treatments.
Chemotherapy
Multiple Regimens for Metastatic Pancreatic Cancer
Recruiting3 awardsPhase 3
La Jolla, California
This trial is designed to compare multiple investigational regimens against standard of care in metastatic pancreatic cancer patients, in order to determine which, if any, patients benefit from each investigational arm. Secondary objectives include determining short- and long-term safety signals of each investigational arm, as well as progression-free survival and response rates.
Alkylating agents
Perioperative Chemotherapy for Pancreatic Cancer
Recruiting4 awardsPhase 3
Mobile, Alabama
This trial compares perioperative chemotherapy (given before and after surgery) versus adjuvant chemotherapy (given after surgery) for the treatment of pancreatic cancer that can be removed by surgery.
Trials With No Placebo
CAR T-cell Therapy
A2B530 CAR T Therapy for Solid Cancers
Recruiting1 awardPhase 1 & 2
Los Angeles, California
This trial tests A2B530, a treatment using modified immune cells from the patient, in adults with hard-to-treat cancers like colorectal, pancreatic, and lung cancer. The treatment aims to target and kill cancer cells while protecting healthy cells.
Monoclonal Antibodies
SGN-BB228 for Melanoma
Recruiting1 awardPhase 1
Denver, Colorado
This trial is testing a new drug called SGN-BB228 to see if it can help treat difficult-to-treat cancers like melanoma and other solid tumors. The study will determine the safest amount of the drug to give and check if it works in shrinking or eliminating these tumors. The goal is to find a new treatment option for patients whose cancers are not responding to current therapies.
MDM2 Inhibitor
Brigimadlin for Solid Cancers
Recruiting1 awardPhase 2
Washington, District of Columbia
This trial is testing a medicine called BI 907828 for adults with advanced cancer in the biliary tract, pancreas, lung, or bladder who have no other treatment options. The medicine is taken as a tablet periodically and works by blocking a protein that helps cancer cells grow.
CAR T-cell Therapy
TC-510 Cell Therapy for Cancer
Recruiting1 awardPhase 1 & 2
Nashville, Tennessee
This trial tests TC-510, a therapy using a patient's own modified T cells to target and attack cancer cells. It is aimed at patients with cancers that are hard to treat with standard methods. The modified T cells are designed to recognize specific proteins on cancer cells and get an extra boost to kill them.
Small Molecule Inhibitor
LY3537982 for Cancer
Recruiting1 awardPhase 1 & 2
Indianapolis, Indiana
This trial is testing a new drug called LY3537982 in cancer patients with the KRAS G12C mutation. It targets this mutation to stop cancer cells from growing. The study includes patients who haven't responded to other treatments or cannot tolerate them. LY3537982 is a new drug targeting the KRAS G12C mutation, similar to previously approved drugs like sotorasib and adagrasib.
View More Related Trials
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.