Procedure
Metabolic Surgery for Type 2 Diabetes
Recruiting1 awardPhase 1 & 2
Aurora, Colorado
This trial is testing whether or not a vertical sleeve gastrectomy, a type of weight loss surgery, can help improve Type 2 diabetes in youth by looking at changes in things like insulin resistance, glycemic control, beta-cell function, and cardiovascular health.
Behavioural Intervention
Aerobic Exercise for Type 2 Diabetes
Recruiting1 award3 criteria
Baltimore, Maryland
This trial is designed to study how well exercise training works to improve cardiovascular function in people with type 2 diabetes, as well as the mechanisms underlying Endothelial Progenitor Cell (EPC) dysfunction in this population.
Popular Filters
Trials for T2D Patients
Angiotensin II Receptor Blocker, COX-2 Inhibitor, Biguanide
Valsartan + Celecoxib + Metformin for Type 2 Diabetes
Recruiting3 awardsPhase 1 & 2
Albany, New York
This trial is evaluating the safety, tolerability and superiority of RK-01, a valsartan plus celecoxib dual add-on to metformin-HCL XR over metformin in newly diagnosed and obese adult type 2 diabetes patients with high blood pressure, arthritis and inadequate glycemic control with metformin monotherapy, diet and exercise. The objective is to assess the effect of RK-01 on hemoglobin A1c (HbA1c) levels, beta cell function and insulin resistance with co-administration of valsartan, celecoxib and metformin-HCl X
Trials for Prediabetes Patients
Behavioural Intervention
Morning vs Evening Exercise for Prediabetes
Recruiting1 award
Aurora, Colorado
"This trial aims to study how exercising at different times of the day affects metabolism, sleep, and other factors. Participants will go through screening visits, follow specific diets, complete exercise conditions in a random order
Behavioral Intervention
Small Steps for Big Changes Program for Prediabetes
Recruiting1 award4 criteria
Kelowna, British Columbia
This trial evaluates the effectiveness of the 'Small Steps for Big Changes' (SSBC) program, designed to help people with prediabetes improve their diet and exercise habits. The goal is to see if these changes can lower blood sugar levels, reduce weight, and decrease waist size over time. Participants receive personalized guidance and support from trainers at YMCA locations. The 'Small Steps for Big Changes' (SSBC) program emphasizes behavior change techniques and motivational interviewing to help adults at risk for type 2 diabetes.
NAD+ precursor
NAD Augmentation for Diabetic Kidney Disease
Recruiting0 awardsPhase 2
Boston, Massachusetts
This trial is testing whether NMN, a compound that may improve cell function, can help older adults with type 2 diabetes and high urine protein levels. The goal is to see if NMN can reduce kidney damage by improving cell energy production. Participants will receive NMN to compare the effects.
Potassium Channel Opener
Diazoxide for Type 2 Diabetes
Recruiting0 awardsPhase 2
Bronx, New York
This trial is testing diazoxide, a drug that activates parts of the brain, on people with type 2 diabetes. The goal is to see if it can help reduce the amount of glucose produced by the liver. By doing so, it may help manage high blood sugar levels in these patients. Diazoxide has been shown to improve blood sugar levels, help with weight loss, and affect certain genes in animal studies.
Procedure
Surgical vs. Lifestyle Interventions for Type 2 Diabetes
Recruiting1 award5 criteria
Pittsburgh, Pennsylvania
This trial is being done to compare the effectiveness of two types of bariatric surgery against an intensive lifestyle intervention in promoting weight loss and improvements in Type 2 diabetes in moderately obese patients.
Phase 3 Trials
Ertugliflozin for Pediatric Type 2 Diabetes
Recruiting1 awardPhase 3
Birmingham, Alabama
This trial will study whether ertugliflozin is safe and effective in children with Type 2 Diabetes who are already taking metformin and/or insulin. The goal is to see if ertugliflozin can help lower HbA1C levels more than placebo after 24 weeks.
GLP-1 Receptor Agonist
Oral Semaglutide for Type 2 Diabetes in Youth
Recruiting1 awardPhase 3
Los Angeles, California
This trial is testing a new diabetes medicine called semaglutide. It focuses on children and teenagers with type 2 diabetes to see if the new medicine is safe and effective. Semaglutide helps control blood sugar levels, which is crucial for managing diabetes. It has been shown to improve blood sugar control and promote weight loss in patients with type 2 diabetes.
Combination Drug
IcoSema for Type 2 Diabetes
Recruiting2 awardsPhase 3
Birmingham, Alabama
This trial will test a new weekly injection called IcoSema, which combines two drugs, in people with type 2 diabetes. The goal is to see if it controls blood sugar better than the existing drug, semaglutide. Participants will be randomly assigned to receive either IcoSema or semaglutide for several months.
Trials With No Placebo
Hormone Therapy
Continuous Glucose Monitoring and Insulin for Ketosis-Prone Diabetes
Recruiting3 awardsPhase 4
Atlanta, Georgia
This trial aims to measure how blood sugar levels change daily during treatment for a specific type of diabetes called ketosis-prone diabetes (KPDM). Researchers will use a mathematical model to explain how KPDM
Monoclonal Antibodies
Aflibercept for Diabetic Macular Edema
Recruiting3 awardsPhase 4
Fullerton, California
This trial investigates the effects of different treatments on patients with diabetic macular edema (DME) who have undergone vitrectomy surgery. The study found that anti-VEGF therapy, particularly ran
Behavioural Intervention
Morning vs Evening Exercise for Prediabetes
Recruiting1 award
Aurora, Colorado
"This trial aims to study how exercising at different times of the day affects metabolism, sleep, and other factors. Participants will go through screening visits, follow specific diets, complete exercise conditions in a random order
Behavioral Intervention
Small Steps for Big Changes Program for Prediabetes
Recruiting1 award4 criteria
Kelowna, British Columbia
This trial evaluates the effectiveness of the 'Small Steps for Big Changes' (SSBC) program, designed to help people with prediabetes improve their diet and exercise habits. The goal is to see if these changes can lower blood sugar levels, reduce weight, and decrease waist size over time. Participants receive personalized guidance and support from trainers at YMCA locations. The 'Small Steps for Big Changes' (SSBC) program emphasizes behavior change techniques and motivational interviewing to help adults at risk for type 2 diabetes.
View More Related Trials
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.