Popular Trials
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Trials for FA Patients
Behavioural Intervention
Respiratory Training for Friedreich's Ataxia
This trial will study patients with Friedreich's Ataxia who will undergo respiratory strength training for 12 weeks. The study will have two research visits - one at the beginning and one at the end
Quinone Analog
Vatiquinone for Friedreich Ataxia
This trial is testing the long-term safety and effectiveness of vatiquinone in people with Friedreich ataxia who have already used this medication. The goal is to ensure it remains safe and helpful over an extended period. Idebenone, a predecessor to vatiquinone, has been used in Friedreich's ataxia patients and shown positive effects on cardiac hypertrophy.
Trials With No Placebo
Behavioural Intervention
Respiratory Training for Friedreich's Ataxia
This trial will study patients with Friedreich's Ataxia who will undergo respiratory strength training for 12 weeks. The study will have two research visits - one at the beginning and one at the end
Quinone Analog
Vatiquinone for Friedreich Ataxia
This trial is testing the long-term safety and effectiveness of vatiquinone in people with Friedreich ataxia who have already used this medication. The goal is to ensure it remains safe and helpful over an extended period. Idebenone, a predecessor to vatiquinone, has been used in Friedreich's ataxia patients and shown positive effects on cardiac hypertrophy.
Gene Therapy
Gene Therapy for Cardiomyopathy in Friedreich's Ataxia
This trial will test a new gene therapy for Friedreich's Ataxia, a rare degenerative disease. The therapy will be delivered intravenously and will be evaluated for safety and efficacy over a 5 year period.
Frequently Asked Questions
Introduction to friedreich ataxia
What are the top hospitals conducting friedreich ataxia research?
In the world of medical research, hospitals across the United States are making remarkable strides in combating friedreich ataxia, a rare genetic disorder that affects coordination and muscle control. Among them is the renowned Children's Hospital of Philadelphia, located in the vibrant city of Philadelphia. This prestigious institution currently has three active clinical trials dedicated to friedreich ataxia and an impressive history of 14 completed trials focused on this condition. Their commitment to advancing treatments for friedreich ataxia began with their first recorded trial in 2013.
On the other side of the country, UCLA in Los Angeles also stands as a beacon of hope for those affected by this debilitating disorder. With three ongoing clinical trials and four previously conducted studies since their inaugural friedreich ataxia trial in 2015, UCLA is actively working towards unraveling the mysteries surrounding this condition.
Heading south to Tampa, Florida, we find the University of South Florida taking significant steps forward through its dedication to researching friedreich ataxia. Currently engaged in three active clinical trials and having completed ten previous investigations since initiating their very first study back in 2009; they continue striving to improve outcomes for patients battling this challenging disease.
The University of Iowa adds itself into this elite group by conducting three active clinical tests focusing on fighting friedreich ataxia after embarking upon its journey just last year recording initial testing against it during2020.Their persistent commitment towards seeking breakthroughs amidst adversity deserves commendation.
It’s worth mentioning that The Children's Hospital of Philadelphia makes another appearance on our list with its unwavering dedication toward understanding and treating fryiedriech Atazie . As one can tell from these numbers indicating not only presence but consistent efforts - such activities denote promising progress which every patient eagerly awaits as each triumph brings hope closer than ever before
Which are the best cities for friedreich ataxia clinical trials?
When it comes to friedreich ataxia clinical trials, several cities in the United States are leading the way in research and treatment. Philadelphia, Pennsylvania, stands out with 8 active trials investigating treatments like Vatiquinone, Part A - Cohort 2, and High Dose LX2006. Los Angeles, California; Tampa, Florida; Iowa City, Iowa; and Gainesville, Florida also have ongoing studies focused on similar interventions such as Vatiquinone and Omaveloxolone Capsules. These cities offer individuals living with friedreich ataxia opportunities to participate in cutting-edge clinical trials that may lead to breakthroughs in managing this condition.
Which are the top treatments for friedreich ataxia being explored in clinical trials?
Friedreich ataxia, a debilitating neurodegenerative disorder, has seen significant progress in clinical trials with promising treatments emerging. Leading the charge is vatiquinone, currently being explored in three active trials specifically targeting this condition. Introduced in 2020, it has already made its mark as one of the top contenders for treating friedreich ataxia. Hot on its heels are high dose LX2006 and AAVrh.10hFXN gene transfer vector—both recently listed in 2022 and showing great potential through their involvement in one active trial each for friedreich ataxia. These groundbreaking therapies offer new hope to individuals living with this challenging disease and pave the way towards improved treatment options.
What are the most recent clinical trials for friedreich ataxia?
Recent clinical trials offer hope and potential advancements in the treatment of Friedreich ataxia, a debilitating neurodegenerative disorder. One notable trial involves vatiquinone, which has shown promising results in both Phase 3 and Phase 2 studies for Friedreich ataxia patients. Another investigational drug being explored is DT-216, with multiple dose administration showing promise in Phase 1 trials. Additionally, CTI-160l is undergoing testing in Phase 2 to assess its efficacy for treating this condition. Moreover, high-dose LX2006 has entered combined Phase 1 and Phase 2 clinical trials as a potential therapeutic option for individuals with Friedreich ataxia—thus offering renewed optimism to those affected by this challenging disease.
What friedreich ataxia clinical trials were recently completed?
A recent milestone has been achieved in the pursuit of improved treatments for friedreich ataxia. Design Therapeutics successfully completed a clinical trial investigating the potential of DT-216 in March 2022. This exciting development highlights the dedication and progress made by researchers in their efforts to combat this debilitating condition. The completion of this trial brings hope for individuals living with friedreich ataxia and offers promise for future advancements in treatment options.