Glioblastoma Clinical Trials in Columbia, SC

View the best 10 glioblastoma medical studies in Columbia, South Carolina. Access promising new therapies by applying to a Columbia-based Glioblastoma clinical trial.

Trials in Columbia, South Carolina

Here are the top 10 medical studies for glioblastoma in Columbia, South Carolina

Michael Bask Gill, B Sc

Last Reviewed: December 17th, 2024

Radiation Therapy

Radiation

Recruiting1 awardPhase 2

This trial studies how well dabrafenib and trametinib work after radiation therapy in children and young adults with a specific type of brain tumor. These drugs help stop tumor growth by blocking signals that tell the cells to multiply. Dabrafenib has been developed and tested extensively for a specific type of skin cancer, showing effectiveness both alone and when used with trametinib.

Etoposide +4 More

Topoisomerase Inhibitor

Recruiting1 awardPhase 2

This trial is testing whether adding indoximod to chemotherapy and/or radiation improves outcomes for pediatric brain cancer patients.

Temozolomide +2 More

Alkylating Agent

Recruiting1 awardPhase 2

This trial is studying a combination of drugs as a potential treatment for newly diagnosed malignant glioma. The drugs being studied are veliparib, radiation therapy, and temozolomide.

Optune®

Device

Recruiting1 award12 criteria

This trial is testing a new treatment for brain cancer that combines Optune with radiation and chemotherapy. The goal is to see if this new combination is more effective and has fewer side effects than current treatments.

Ramipril

ACE Inhibitor

Recruiting1 awardPhase 2

This trial is testing whether Ramipril can help cancer patients undergoing chemoradiation treatment by reducing memory loss. Patients will take the drug throughout treatment and for four months after. Memory will be assessed using neurocognitive tests.

APL-101

Small Molecule Inhibitor

Recruiting1 awardPhase 2

This trial is testing APL-101, a new drug, on patients with specific genetic changes in their cancer. These patients often don't respond to typical treatments. The drug aims to block a protein that helps cancer cells grow and spread.

Pembrolizumab +1 More

Monoclonal Antibodies

Recruiting1 awardPhase 1 & 2

This trial is testing a new drug called NGM707, both by itself and with another drug, Pembrolizumab. It targets patients with very advanced or spreading solid tumors. The treatment aims to boost the immune system to better fight cancer.

Photon Beam Radiation Therapy +2 More

Radiation Therapy

Recruiting1 awardPhase 2

This trial is studying how well two types of radiation therapy work compared to standard radiation therapy when given with temozolomide in patients with newly diagnosed glioblastoma.

Ipilimumab +2 More

Checkpoint Inhibitor

Recruiting1 awardPhase 2 & 3

This trial is testing whether adding immunotherapy to radiation therapy can help people with newly diagnosed glioblastoma that has an unmethylated MGMT.

Lomustine +2 More

Alkylating agents

Recruiting2 awardsPhase 3

This trial is comparing the effect of adding lomustine to temozolomide and radiation therapy versus temozolomide and radiation therapy alone in treating newly diagnosed MGMT methylated glioblastoma.

Popular Filters

Trials With No Placebo

Alkylating agents

Lomustine + Standard Therapy for Glioblastoma

Recruiting2 awardsPhase 3

Baltimore, Maryland

This trial is comparing the effect of adding lomustine to temozolomide and radiation therapy versus temozolomide and radiation therapy alone in treating newly diagnosed MGMT methylated glioblastoma.

Monoclonal Antibodies

NGM707 + Pembrolizumab for Cancer

Recruiting1 awardPhase 1 & 2

Greenville, South Carolina

This trial is testing a new drug called NGM707, both by itself and with another drug, Pembrolizumab. It targets patients with very advanced or spreading solid tumors. The treatment aims to boost the immune system to better fight cancer.

Device

Optune + Radiation & Chemotherapy for Brain Cancer

Recruiting1 award12 criteria

Charlotte, North Carolina

This trial is testing a new treatment for brain cancer that combines Optune with radiation and chemotherapy. The goal is to see if this new combination is more effective and has fewer side effects than current treatments.

Checkpoint Inhibitor

Ipilimumab + Nivolumab + Radiation for Glioblastoma

Recruiting1 awardPhase 2 & 3

Savannah, Georgia

This trial is testing whether adding immunotherapy to radiation therapy can help people with newly diagnosed glioblastoma that has an unmethylated MGMT.

Topoisomerase Inhibitor

Indoximod + Chemotherapy/Radiation for Pediatric Brain Cancer

Recruiting1 awardPhase 2

Augusta, Georgia

This trial is testing whether adding indoximod to chemotherapy and/or radiation improves outcomes for pediatric brain cancer patients.

Radiation

Dabrafenib + Trametinib After Radiation for Brain Cancer

Recruiting1 awardPhase 2

Columbia, South Carolina

This trial studies how well dabrafenib and trametinib work after radiation therapy in children and young adults with a specific type of brain tumor. These drugs help stop tumor growth by blocking signals that tell the cells to multiply. Dabrafenib has been developed and tested extensively for a specific type of skin cancer, showing effectiveness both alone and when used with trametinib.

View More Related Trials

Radiation Therapy +1 More

Photon Beam Radiation Therapy +2 More

View more glioblastoma clinical trials columbia

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Frequently Asked Questions

Do I need insurance to participate in a trial?

Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).

Is there any support for travel costs?

Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.

Will I know what medication I am taking?

This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.

How long do clinical trials last?

Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.

Do you verify all the trials on your website?

All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.

How quickly will I hear back from a clinical trial?

Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.