Glioblastoma Clinical Trials in High Point, NC

View the best 10 glioblastoma medical studies in High Point, North Carolina. Access promising new therapies by applying to a High Point-based Glioblastoma clinical trial.

Trials in High Point, North Carolina

Here are the top 10 medical studies for glioblastoma in High Point, North Carolina

Selinexor +1 More

Selective Inhibitor of Nuclear Export

Recruiting1 awardPhase 1 & 2

This trial tests selinexor with temozolomide for patients whose brain cancer has returned. Selinexor blocks a protein that helps cancer cells grow, and temozolomide damages their DNA to kill them or stop their growth. Temozolomide is a DNA methylating drug currently used as a first-line treatment in glioblastoma therapy.

IGV-001 +2 More

Cell Immunotherapy

Recruiting0 awardsPhase 2

This trial will compare a new treatment for glioblastoma to placebo to see if it extends survival.

NSC-CRAd-S-pk7

Virus Therapy

Recruiting1 awardPhase 1

This trial is testing a new cancer treatment consisting of neural stem cells that carry a virus. The hope is that this will kill more tumor cells than the current standard of care.

VAL-083 +7 More

Alkylating agents

Recruiting1 awardPhase 2 & 3

This trial is testing various treatments for patients with newly diagnosed or returning brain cancer. It adjusts treatments based on how well patients are doing to find the most effective options. The goal is to improve survival rates by matching the best treatments to specific patient types.

Olaparib

PARP Inhibitor

Recruiting1 awardPhase 2

This trial will study how well olaparib works in treating patients with certain types of cancer that have spread and usually cannot be controlled with treatment. Olaparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Ropidoxuridine

Radiosensitizer

Recruiting1 awardPhase 2

"This trial is testing a drug called ropidoxuridine to see if it can make radiation therapy more effective in patients with a specific type of brain cancer. The study will look at how safe and

CAR.B7-H3T cells

CAR T-cell Therapy

Recruiting1 awardPhase 1

This trial is testing if it's safe to use CAR.B7-H3T cells, a treatment for glioblastoma that hasn't been tested on humans before.

Atezolizumab

Checkpoint Inhibitor

Recruiting1 awardPhase 2

"This trial aims to see if giving atezolizumab before surgery can help patients with recurrent glioblastoma and low mutational burden."

ST101

Virus Therapy

Recruiting1 awardPhase 1 & 2

This trial tests a new drug, ST101, given to patients with advanced cancers who haven't responded to other treatments. The study aims to find the safest and most effective dose. It includes patients with specific types of breast cancer, melanoma, brain cancer, and prostate cancer.

BGB-290 +1 More

PARP Inhibitor

Recruiting1 awardPhase 1

This trial studies the safety and best dose of BGB-290 and temozolomide in treating young people with a specific type of brain tumor. BGB-290 blocks enzymes needed for tumor growth, while temozolomide kills or stops cancer cells from growing. The goal is to find out if this combination works better for these patients.

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Trials With No Placebo

mTOR Inhibitor

Ribociclib + Everolimus for Brain Tumors

Recruiting1 awardPhase 2

Durham, North Carolina

This trial is testing whether the combination of ribociclib and everolimus can help children and young adults with aggressive brain tumors live longer. Everolimus is a medication that has been approved for treating various cancers. These drugs are taken by mouth and work by stopping cancer cells from growing. The study focuses on patients whose tumors have specific genetic changes that make them hard to treat with standard therapies.

Alkylating agents

OKN-007 + Temozolomide for Recurrent Brain Cancer

Recruiting1 awardPhase 2

Winston-Salem, North Carolina

This trial is testing a new drug called OKN-007 combined with a chemotherapy drug, temozolomide, in patients whose brain cancer has returned after standard treatments. OKN-007 may help reduce tumor growth and make the chemotherapy more effective. Temozolomide is effective in treating malignant brain tumors.

Alkylating agents

Multiple Therapies for Glioblastoma

Recruiting1 awardPhase 2 & 3

Winston-Salem, North Carolina

This trial is testing various treatments for patients with newly diagnosed or returning brain cancer. It adjusts treatments based on how well patients are doing to find the most effective options. The goal is to improve survival rates by matching the best treatments to specific patient types.

Radiation

Dabrafenib + Trametinib After Radiation for Brain Cancer

Recruiting1 awardPhase 2

Winston-Salem, North Carolina

This trial studies how well dabrafenib and trametinib work after radiation therapy in children and young adults with a specific type of brain tumor. These drugs help stop tumor growth by blocking signals that tell the cells to multiply. Dabrafenib has been developed and tested extensively for a specific type of skin cancer, showing effectiveness both alone and when used with trametinib.

PARP Inhibitor

PARP Inhibitor + Temozolomide for Brain Cancer

Recruiting1 awardPhase 1

Durham, North Carolina

This trial studies the safety and best dose of BGB-290 and temozolomide in treating young people with a specific type of brain tumor. BGB-290 blocks enzymes needed for tumor growth, while temozolomide kills or stops cancer cells from growing. The goal is to find out if this combination works better for these patients.

PARP Inhibitor

Olaparib for Advanced Cancer

Recruiting1 awardPhase 2

Chapel Hill, North Carolina

This trial will study how well olaparib works in treating patients with certain types of cancer that have spread and usually cannot be controlled with treatment. Olaparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Frequently Asked Questions

Do I need insurance to participate in a trial?

Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).

Is there any support for travel costs?

Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.

Will I know what medication I am taking?

This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.

How long do clinical trials last?

Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.

Do you verify all the trials on your website?

All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.

How quickly will I hear back from a clinical trial?

Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.