Glioblastoma Clinical Trials in High Point, NC

View the best 10 glioblastoma medical studies in High Point, North Carolina. Access promising new therapies by applying to a High Point-based Glioblastoma clinical trial.

Trials in High Point, North Carolina

Here are the top 10 medical studies for glioblastoma in High Point, North Carolina

Michael Bask Gill, B Sc

Last Reviewed: December 14th, 2024

Ramipril

ACE Inhibitor

Recruiting1 awardPhase 2

This trial is testing whether Ramipril can help cancer patients undergoing chemoradiation treatment by reducing memory loss. Patients will take the drug throughout treatment and for four months after. Memory will be assessed using neurocognitive tests.

Retifanlimab +3 More

Immune Checkpoint Inhibitor

Recruiting1 awardPhase 2

This trial is testing a combination of treatments including a new drug, radiation therapy, and other medications for patients with aggressive brain cancer that has returned. The goal is to boost the body's immune system to better fight the cancer, shrink tumors, and help patients live longer.

IGV-001 +2 More

Cell Immunotherapy

Recruiting0 awardsPhase 2

This trial will compare a new treatment for glioblastoma to placebo to see if it extends survival.

NSC-CRAd-S-pk7

Virus Therapy

Recruiting1 awardPhase 1

This trial is testing a new cancer treatment consisting of neural stem cells that carry a virus. The hope is that this will kill more tumor cells than the current standard of care.

VAL-083 +7 More

Alkylating agents

Recruiting1 awardPhase 2 & 3

This trial is testing various treatments for patients with newly diagnosed or returning brain cancer. It adjusts treatments based on how well patients are doing to find the most effective options. The goal is to improve survival rates by matching the best treatments to specific patient types.

Olaparib

PARP Inhibitor

Recruiting1 awardPhase 2

This trial will study how well olaparib works in treating patients with certain types of cancer that have spread and usually cannot be controlled with treatment. Olaparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Exablate Model 4000

Focused Ultrasound

Recruiting1 award

This trial aims to test the safety and effectiveness of using the Exablate device to temporarily open the blood-brain barrier in patients with suspected Glioblastoma. By doing this, doctors can collect fluid from the brain to check for cancer cells. The study will take place at up to 25 centers in the US.

CAR.B7-H3T cells

CAR T-cell Therapy

Recruiting1 awardPhase 1

This trial is testing if it's safe to use CAR.B7-H3T cells, a treatment for glioblastoma that hasn't been tested on humans before.

Atezolizumab

Checkpoint Inhibitor

Recruiting1 awardPhase 2

"This trial aims to see if giving atezolizumab before surgery can help patients with recurrent glioblastoma and low mutational burden."

ST101

Virus Therapy

Recruiting1 awardPhase 1 & 2

This trial tests a new drug, ST101, given to patients with advanced cancers who haven't responded to other treatments. The study aims to find the safest and most effective dose. It includes patients with specific types of breast cancer, melanoma, brain cancer, and prostate cancer.

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Trials With No Placebo

CAR T-cell Therapy

BRiTE for Glioblastoma

Recruiting1 awardPhase 1

Durham, North Carolina

This trial is testing a new treatment called BRiTE for patients with aggressive brain cancer that have a specific mutation. BRiTE helps the immune system recognize and destroy cancer cells by connecting immune cells directly to the cancer.

Anthracenedione

Berubicin for Glioblastoma

Recruiting1 awardPhase 2

Durham, North Carolina

This trial will compare the effect of two cancer drugs, berubicin and lomustine, on overall survival in patients with glioblastoma multiforme (GBM) who have failed standard first line therapy. A futility analysis will be performed after approximately 30-50% of planned patients have completed the primary endpoint at 6 months.

Virus Therapy

ST101 for Advanced Cancer

Recruiting1 awardPhase 1 & 2

Durham, North Carolina

This trial tests a new drug, ST101, given to patients with advanced cancers who haven't responded to other treatments. The study aims to find the safest and most effective dose. It includes patients with specific types of breast cancer, melanoma, brain cancer, and prostate cancer.

Device

Optune + Radiation & Chemotherapy for Brain Cancer

Recruiting1 award12 criteria

Winston-Salem, North Carolina

This trial is testing a new treatment for brain cancer that combines Optune with radiation and chemotherapy. The goal is to see if this new combination is more effective and has fewer side effects than current treatments.

Checkpoint Inhibitor

Ipilimumab + Nivolumab + Radiation for Glioblastoma

Recruiting1 awardPhase 2 & 3

Savannah, Georgia

This trial is testing whether adding immunotherapy to radiation therapy can help people with newly diagnosed glioblastoma that has an unmethylated MGMT.

Alkylating agents

OKN-007 + Temozolomide for Recurrent Brain Cancer

Recruiting1 awardPhase 2

Winston-Salem, North Carolina

This trial is testing a new drug called OKN-007 combined with a chemotherapy drug, temozolomide, in patients whose brain cancer has returned after standard treatments. OKN-007 may help reduce tumor growth and make the chemotherapy more effective. Temozolomide is effective in treating malignant brain tumors.

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Frequently Asked Questions

Do I need insurance to participate in a trial?

Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).

Is there any support for travel costs?

Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.

Will I know what medication I am taking?

This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.

How long do clinical trials last?

Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.

Do you verify all the trials on your website?

All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.

How quickly will I hear back from a clinical trial?

Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.