Lonigutamab for Thyroid Eye Disease
Recruiting0 awardsPhase 1 & 2
Beverly Hills, California
This trial is testing a new medication called lonigutamab to help people with Thyroid Eye Disease (TED). TED causes eye problems due to thyroid issues. Lonigutamab may work by reducing inflammation and other symptoms in the eyes.
Monoclonal Antibodies
Teprotumumab for Thyroid Eye Disease
Recruiting2 awardsPhase 4
Aurora, Colorado
This trial tests the safety and effectiveness of teprotumumab, an IV medication, in adults with Thyroid Eye Disease. It aims to find the best treatment period and assess the need for additional treatment. The medication helps by reducing inflammation and tissue changes in the eyes. Teprotumumab, initially developed for tumor treatment, was later repurposed for thyroid eye disease and approved by the USFDA.
Anti-VEGF Therapy
Anti-VEGF Therapy for Thyroid Eye Disease
Recruiting0 awardsPhase 2
Boston, Massachusetts
This trial is testing the safety of injecting a medication called aflibercept, mixed with either a saltwater solution or an enzyme, around the eyes of patients with acute Thyroid Eye Disease. The goal is to see if this treatment can safely reduce swelling and inflammation. Patients will receive multiple injections and be monitored for any side effects. Aflibercept has been used in various retinal diseases, including macular edema and age-related macular degeneration.
Monoclonal Antibodies
Teprotumumab for Graves' Eye Disease
Recruiting1 awardPhase 3
San Diego, California
This trial involves testing a new treatment for proptosis in a blinded study where some participants will receive the treatment and others will receive a placebo. Participants who do not respond to the initial treatment may have
Monoclonal Antibodies
Satralizumab for Thyroid Eye Disease
Recruiting1 awardPhase 3
Philadelphia, Pennsylvania
This trial is testing an injectable medicine called satralizumab for people with thyroid eye disease. The medicine works by blocking a protein that causes inflammation, which can help reduce swelling and discomfort in the eyes. The study aims to see how safe and effective this treatment is for these patients.
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Phase 3 Trials
Monoclonal Antibodies
Satralizumab for Thyroid Eye Disease
Recruiting1 awardPhase 3
Los Angeles, California
This trial is testing an injectable medicine called satralizumab for people with thyroid eye disease. The medicine works by blocking a protein that causes inflammation, which can help reduce swelling and discomfort in the eyes. The study aims to see how safe and effective this treatment is for these patients.
Monoclonal Antibodies
Batoclimab for Thyroid Eye Disease
Recruiting2 awardsPhase 3
Glendora, California
This trial is an extension study for participants who have completed earlier studies. There are two groups in the study: an observational group and a treatment group. The observational group will look at how long the improvement
Small Molecule Inhibitor
Linsitinib for Thyroid Eye Disease
Recruiting0 awardsPhase 2 & 3
Miami, Florida
This trial studies the safety and effectiveness of linsitinib, an oral medication taken regularly, in patients with moderate to severe thyroid eye disease. Linsitinib works by blocking a protein that contributes to the disease, aiming to reduce symptoms and improve eye health.
Trials With No Placebo
Monoclonal Antibodies
Batoclimab for Thyroid Eye Disease
Recruiting2 awardsPhase 3
Glendora, California
This trial is an extension study for participants who have completed earlier studies. There are two groups in the study: an observational group and a treatment group. The observational group will look at how long the improvement
Cervical Collar Device for Thyroid Disorders
Recruiting1 award2 criteria
Baltimore, Maryland
This trial is testing a device that is worn around the neck and measures radioiodine exposure to help estimate the amount of iodine-131 that a person needs for treatment of thyroid disorders while minimizing risks of comorbidities.
Tyrosine Kinase Inhibitor
Linsitinib for Thyroid Eye Disease
Recruiting1 awardPhase 2 & 3
Miami, Florida
This trial is testing linsitinib, a medication, on patients who did not improve or got worse after previous treatment. The goal is to see if linsitinib can help these patients by blocking certain proteins that make their condition worse.
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.