Behavioural Intervention
Smoking Cessation Cognitive Behavioral Therapy (CBT) for Post-Traumatic Stress Disorder (PTSD)
This trial will test a treatment that combines cognitive processing therapy with cognitive-behavioral counseling for smoking cessation, contingency management, and smoking cessation medication to see if it is more effective than just cognitive processing therapy for reducing smoking among veterans with PTSD.
Behavioral Intervention
Cognitive-Behavioral Treatment for PTSD-Related Nightmares in Veterans
This trial is investigating whether a cognitive-behavioral treatment can reduce trauma-related nightmares in Veterans. The study uses extended, in-home sleep monitoring to capture sleep data associated with nightmare reports, and assess how these features are altered throughout the treatment.
Psychedelic
Psilocybin for PTSD
This trial aims to test if using psilocybin along with therapy can safely and effectively treat PTSD in U.S. Military Veterans. Psilocybin helps change brain activity, making it easier for veterans to process their trauma during therapy.
Behavioural Intervention
Positive Memory Therapy for PTSD
This trial tests a new method called PPMT that helps people with PTSD by focusing on happy memories. It targets those who haven't fully benefited from existing treatments. By remembering and discussing positive experiences, it aims to reduce symptoms and improve mood. PPMT is a novel technique developed to help PTSD patients by focusing on positive memories, and it has been piloted among trauma-exposed individuals.
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Trials for PTSD Patients
Behavioural Intervention
Cognitive Processing + Self-Compassion Therapies for PTSD
This trialwill assess whether Cognitive Processing Therapy (CPT) and Self-Compassion (SC) interventions reduce trauma-related mental contamination and PTSD symptoms among individuals who experienced sexual trauma.
Behavioral Intervention
START for Post-Traumatic Stress Disorder
This trial tests a new treatment called START, which helps veterans with PTSD reduce their reliance on anxiety-avoiding behaviors. It targets veterans who avoid traditional PTSD therapies. By reducing these 'safety aids,' the treatment aims to help them face their fears and feel less anxious over time.
Trials for Major Depressive Disorder Patients
Behavioral Intervention
Whole Health Intervention for PTSD
This trial tests Omnis Salutis, a program for recent veterans of the Afghanistan and Iraq conflicts. The program helps veterans set and share their health goals with doctors and support systems to improve their well-being.
Behavioral Intervention
Online Cognitive Behavioural Therapy for Anxiety
"This trial is testing an online therapy program for public safety workers. The program is self-guided and tailored to each individual, with some participants also having access to social learning resources."
Behavioural Intervention
SYNC Program for Psychosocial Functioning in Foster Youth
This trial will deploy a program to improve mental health & service use of foster youth before & after exiting care. It aims to increase coping self-efficacy & help-seeking attitudes, & test if the program is effective in improving mental health & service use.
Behavioural Intervention
Mobile App Therapy for PTSD and Depression
"This trial aims to test a mobile app designed to help Veterans with PTSD and depression improve their functioning. The app is based on a talk therapy approach that has been effective in the past. By using the
Trials With No Placebo
Behavioural Intervention
Cognitive Processing + Self-Compassion Therapies for PTSD
This trialwill assess whether Cognitive Processing Therapy (CPT) and Self-Compassion (SC) interventions reduce trauma-related mental contamination and PTSD symptoms among individuals who experienced sexual trauma.
Behavioral Intervention
START for Post-Traumatic Stress Disorder
This trial tests a new treatment called START, which helps veterans with PTSD reduce their reliance on anxiety-avoiding behaviors. It targets veterans who avoid traditional PTSD therapies. By reducing these 'safety aids,' the treatment aims to help them face their fears and feel less anxious over time.
Behavioral Intervention
AIR Sleep Treatment for PTSD-related Sleep Disorders
This trial uses video calls to help veterans with PTSD, sleep apnea, and insomnia improve their sleep and daily functioning. The main goal is to enhance their quality of life by teaching better sleep habits. Veterans will also give feedback on how practical and acceptable they find the treatment.
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Frequently Asked Questions
Introduction to ptsd
What are the top hospitals conducting ptsd research?
When it comes to advancing the understanding and treatment of post-traumatic stress disorder (PTSD), several hospitals are leading the charge. In Lexington, Kentucky, the University of Kentucky Clinic for Emotional Health (CEH) is making significant strides with three ongoing clinical trials focused on PTSD. Although relatively new to studying this condition, having recorded their first trial in 2020, CEH is committed to improving outcomes for individuals affected by PTSD.
Moving over to Houston, Texas, the Michael E. DeBakey VA Medical Center has also dedicated itself to this important research area. With three active PTSD trials and a total of 12 completed trials since their initial investigation in 2011, they have been at the forefront of exploring novel approaches for treating this complex disorder.
Philadelphia's Corporal Michael J. Crescenz VA Medical Center has taken up the challenge as well with two ongoing PTSD trials and four completed studies dating back to their first trial in 2009. Their efforts contribute significantly towards developing effective interventions for those living with PTSD.
In Minneapolis, Minnesota's VA Health Care System has conducted extensive research into PTSD as evidenced by its impressive record of 15 past studies along with two currently active trials. Having initiated their first study on this topic in 2009 alongside other leading institutions across the country clearly demonstrates their commitment towards alleviating symptoms associated with trauma-related disorders.
Last but not least is Salt Lake City's VA Salt Lake City Health Care System which began its exploration into PTSD through a trial conducted in 2014; although relatively new compared to others mentioned here regarding numbers yet plays an essential role nonetheless featuring two currently active investigations among previously held three studies that already contributed valuable insights on how we tackle effectively such cases within Utah region
These esteemed hospitals are actively engaged in groundbreaking research aiming at finding innovative solutions for one of society’s most pressing mental health challenges: post-traumatic stress disorder.With each step forward these medical centers take, they bring hope to those affected by PTSD and contribute to the collective knowledge that will ultimately lead us towards more effective treatments and improved quality of life for individuals touched by trauma
Which are the best cities for ptsd clinical trials?
When it comes to PTSD clinical trials, several cities emerge as frontrunners in research and development. Houston, Texas leads the way with 6 active trials exploring treatments like BI 1358894, Manage Emotions to Reduce Aggression, and Forgiveness-based Writing. Los Angeles, California follows closely behind with 5 ongoing studies focused on interventions such as the NeuroPace® RNS® System and Medtronic Activa PC DBS of the Basolateral Nucleus of the Amygdala. Additionally, San Diego, California and Tampa, Florida both offer promising opportunities for individuals seeking participation in PTSD clinical trials. With their respective programs investigating therapies like Prolonged Exposure Therapy and NightWare Therapeutic System, these cities contribute significantly to advancing our understanding and treatment options for this debilitating condition.
Which are the top treatments for ptsd being explored in clinical trials?
Exciting advancements are occurring in the field of PTSD treatment, particularly within ongoing clinical trials. One standout contender is psilocybin, which has garnered significant attention with two active trials dedicated to exploring its potential for combating PTSD. Since its introduction in 2022, it has already been involved in a total of five clinical trials focused on this specific condition. With promising results emerging from these studies, there is hope that psilocybin may provide new avenues for treating individuals suffering from the debilitating effects of PTSD.
What are the most recent clinical trials for ptsd?
Recent clinical trials offer promising prospects for individuals struggling with post-traumatic stress disorder (PTSD). One such trial involves the use of mismatch reactivation conditioning, a Phase 4 study aiming to identify innovative approaches in PTSD treatment. Additionally, an active drug is undergoing evaluation in both Phase 2 and Phase 3 trials, potentially providing new therapeutic options for patients. Another investigation focuses on the efficacy of Pimavanserin administered at a dose of 34mg orally before bedtime as a potential intervention for PTSD. Furthermore, an open-label infusion study examines the effects of Brexanolone on individuals with PTSD in its Phase 4 stage. Lastly, Psilocybin-assisted therapy shows promise as it undergoes investigation during its Phase 2 trial phase since January 2023. These recent clinical trials hold great significance in advancing our understanding and management of PTSD.
What ptsd clinical trials were recently completed?
Several clinical trials aimed at advancing our understanding and treatment of post-traumatic stress disorder (PTSD) have recently concluded. In December 2021, Alto Neuroscience successfully completed a trial investigating the ALTO-100 PO tablet for PTSD. Similarly, Bionomics Limited wrapped up their study on BNC210 in July 2021, offering hope for new therapeutic options. It is worth noting that Otsuka Pharmaceutical Development & Commercialization conducted two separate trials on Brexpiprazole in October 2019. Furthermore, NYU Langone Health explored the potential benefits of Cannabidiol in September 2019, while The University of Texas Health Science Center at San Antonio investigated Quetiapine Fumarate in February 2019. Lastly, Yale University's trial on Ketamine reached its conclusion back in November 2018. These recent breakthroughs underscore ongoing efforts to improve the lives of those affected by PTSD through cutting-edge research and innovation