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Trials With No Placebo
VEGF Inhibitor
High-Dose Aflibercept for Macular Edema
This trial is testing a higher dose of an eye injection called aflibercept in people with vision problems due to retinal vein occlusion. The goal is to see if a higher dose can be given less frequently while still helping to improve vision. The treatment works by blocking a protein that causes swelling in the eye. Researchers will compare vision improvements and safety between different doses. Aflibercept has been used to treat macular edema secondary to retinal vein occlusion and has shown efficacy in various studies.
Stem Cell Therapy
Stem Cells for Retinal Disease
This trial is testing if injecting special cells from bone marrow into the eye is safe and possible for patients who are permanently blind due to retinal diseases. The hope is that these cells can help fix the damaged parts of their eyes.
Frequently Asked Questions
Introduction to retinal vein occlusion
What are the top hospitals conducting retinal vein occlusion research?
Advancements in the treatment of retinal vein occlusion, a condition that can lead to vision loss, are being made by top hospitals around the world. In Winter Haven, Florida, the Center for Retina and Macular Disease is actively involved in two clinical trials focused on retinal vein occlusion. With a total of four trials conducted thus far since their first recorded trial in 2013, this center is committed to exploring innovative approaches to tackle this eye disorder. Meanwhile, over at St Michael's Hospital in Toronto, Canada's Department of Ophthalmology has also delved into the realm of retinal vein occlusion research. They currently have two active trials underway and have contributed two previous trials since embarking on their journey in 2017.
Across coasts lies Retina Consultants of Orange County located in Fullerton; they are currently engaged with one ongoing trial while having already conducted a noteworthy count of four investigations after initiating their pioneering study as recent as 2018. Excitingly, Mountain View | Ophthalmology situated at Loma Linda enters this field with promising potential as they initiate one groundbreaking investigation that focuses primarily on retinal vein occlusion starting as soon as2023 accompanied by South Coast Retina Center based out Long Beach who join them side-by-side conducting similar exploration commencing from same year focusing entirely upon such cases.
These dedicated hospitals exemplify global efforts to find effective treatments for retinal vein occlusion and improve patients' lives through cutting-edge research initiatives. By pushing boundaries and investigating new possibilities within the field of ophthalmology across different locations worldwide these institutions strive towards attaining breakthroughs which ultimately pave way towards brighter future where visual impairments caused due to retinol veins stop being threatening issues due to availability revolutionary remedies
Which are the best cities for retinal vein occlusion clinical trials?
When it comes to retinal vein occlusion clinical trials, several cities emerge as leading research hubs. Hagerstown, Maryland tops the list with 4 active trials focusing on treatments like Higher Dose Regimen 1 and bevacizumab. Baltimore, Maryland follows closely behind with 3 ongoing studies exploring Higher Dose Regimen 1 and other interventions. Philadelphia, Pennsylvania also boasts 3 active trials investigating Higher Dose Regimen 1 and dexamethasone intravitreal implant among other potential therapies. Meanwhile, San Antonio, Texas and Toronto, Ontario each contribute their own set of promising studies in the field of retinal vein occlusion treatment. These cities serve as valuable locations for individuals seeking participation in cutting-edge clinical trials that may pave the way for improved care options for this condition.
Which are the top treatments for retinal vein occlusion being explored in clinical trials?
The exciting field of retinal vein occlusion research is witnessing active exploration of various treatments in clinical trials. One standout contender is aflibercept, which has shown promise in addressing this condition. Currently, there is one ongoing trial dedicated to evaluating its effectiveness for retinal vein occlusion. Since its listing in 2012, aflibercept has been the subject of nine clinical trials focused on this specific condition. As researchers delve deeper into these studies, they are inching closer towards finding innovative solutions for patients affected by retinal vein occlusions.
What are the most recent clinical trials for retinal vein occlusion?
Exciting advancements in the field of retinal vein occlusion are emerging through recent clinical trials. These studies offer hope for improved treatment options and better outcomes for patients. Notably, a Phase 3 trial has investigated the efficacy of a higher dose regimen as a potential approach to managing retinal vein occlusion. Another promising development is the Phase 2 trial evaluating the use of ANXV - active at a dosage of 2 mg. Furthermore, ongoing research explores the effectiveness of bevacizumab and aflibercept in treating this condition, with Phase 3 and Phase 4 trials respectively seeking to validate their benefits. Additionally, an innovative Phase 1 study examines episcleral celecoxib's potential role in mitigating retinal vein occlusion symptoms. Collectively, these endeavors bring us closer to enhancing patient care for individuals affected by retinal vein occlusion while shedding light on new treatment possibilities.
What retinal vein occlusion clinical trials were recently completed?
Several notable clinical trials focusing on retinal vein occlusion have recently reached completion, demonstrating promising advancements in the field. Hoffmann-La Roche sponsored two significant trials investigating Faricimab, with both studies concluding successfully in March 2021. Another noteworthy trial involved MHU650, supported by Novartis Pharmaceuticals, which concluded in December 2020. Furthermore, Kodiak Sciences Inc completed a trial for KSI-301 in September 2020. Although slightly older but still worth mentioning is the Minocycline study conducted by the National Eye Institute (NEI), which was finalized in March 2012. These collective efforts showcase ongoing research and innovation aimed at enhancing treatment options for individuals affected by retinal vein occlusion.