Popular Trials
Procedure
Myelin Repair Therapy for Multiple Sclerosis
This trial will assess the effects of clemastine fumarate to repair/protect brain lesions in people with acute demyelination, using MRI assessments and a new technique called Ultrashort Echo Time (UTE) MRI.
Antihistamine
Clemastine Fumarate for Multiple Sclerosis
This trial tests Clemastine Fumarate to see if it can repair myelin in patients with relapsing-remitting multiple sclerosis who have chronic brain lesions. The medication helps immature brain cells develop into myelin-producing cells, potentially fixing the damage caused by MS.
Behavioural Intervention
Electrical Spinal Stimulation for Spinal Cord Injury
This trial is testing a new electrical stimulation device to see if it can improve hand motor and sensory function in people with traumatic or degenerative cervical spinal cord injury.
Popular Filters
Trials for Spinal Cord Injury Patients
Electrical Stimulation for Spinal Cord Injury
This trial uses electrical stimulation techniques to help patients with partial spinal cord injuries improve their arm and hand movements. The treatment works by enhancing the timing and coordination of nerve signals, making it easier for the brain and spinal cord to control muscles. Electrical stimulation of the spinal cord has been practiced as a therapy by the medical community for a long time.
Neuroprosthetic Device
Neuroprosthetic System for Spinal Cord Injury
This trial is to test a new, fully implanted device that could help people with cervical spinal cord injuries regain hand function, reach, and trunk function. It is funded by the FDA, NIH, and NINDS.
Behavioral Intervention
Occupational Therapy for Spinal Cord Compression
This trial aims to understand how rehabilitation therapy can improve brain plasticity and neurological function in patients with spinal cord compression. The study will compare patients who receive rehabilitation after spine surgery with those who do not,
Stem Cell Therapy
Stem Cell Therapy + Exoskeleton/Virtual Reality for Spinal Cord Injury
This trial is investigating whether autologous bone marrow derived stem cells can help improve motor or sensory function in people with spinal cord injury. The treatment involves injections of the cells around the area of the injury, as well as an intravenous injection and intranasal placement. Patients may also be assigned to use exoskeletal movement or virtual reality visualization to help improve function.
Trials for CSCI Patients
Electrical Stimulation for Spinal Cord Injury
This trial uses electrical stimulation techniques to help patients with partial spinal cord injuries improve their arm and hand movements. The treatment works by enhancing the timing and coordination of nerve signals, making it easier for the brain and spinal cord to control muscles. Electrical stimulation of the spinal cord has been practiced as a therapy by the medical community for a long time.
Neuroprosthetic Device
Neuroprosthetic System for Spinal Cord Injury
This trial is to test a new, fully implanted device that could help people with cervical spinal cord injuries regain hand function, reach, and trunk function. It is funded by the FDA, NIH, and NINDS.
Behavioral Intervention
Occupational Therapy for Spinal Cord Compression
This trial aims to understand how rehabilitation therapy can improve brain plasticity and neurological function in patients with spinal cord compression. The study will compare patients who receive rehabilitation after spine surgery with those who do not,
Stem Cell Therapy
Stem Cell Therapy + Exoskeleton/Virtual Reality for Spinal Cord Injury
This trial is investigating whether autologous bone marrow derived stem cells can help improve motor or sensory function in people with spinal cord injury. The treatment involves injections of the cells around the area of the injury, as well as an intravenous injection and intranasal placement. Patients may also be assigned to use exoskeletal movement or virtual reality visualization to help improve function.
Trials With No Placebo
Electrical Stimulation for Spinal Cord Injury
This trial uses electrical stimulation techniques to help patients with partial spinal cord injuries improve their arm and hand movements. The treatment works by enhancing the timing and coordination of nerve signals, making it easier for the brain and spinal cord to control muscles. Electrical stimulation of the spinal cord has been practiced as a therapy by the medical community for a long time.
Neuroprosthetic Device
Neuroprosthetic System for Spinal Cord Injury
This trial is to test a new, fully implanted device that could help people with cervical spinal cord injuries regain hand function, reach, and trunk function. It is funded by the FDA, NIH, and NINDS.
Powered Exoskeleton
Powered Exoskeleton for Spinal Cord Injury
This trial is testing a device called Ekso to see if it is safe and effective for people with spinal cord injuries or similar neurological weaknesses. The device helps the person stand, walk, and turn, and sit down. The trial will test if the person using Ekso can safely balance and walk without losing balance, and if they improve in weight shift and other activities.
Radiation Therapy
Stereotactic Radiosurgery for Spinal Cord Compression
This trial is testing a one-time high-dose radiation treatment called Spine Stereotactic Radiosurgery (SSRS) for patients with spinal cord compression from cancer who can't have surgery. The goal is to see if this precise treatment can stop tumor growth and prevent spinal cord injury. Patients will be monitored regularly to check their progress. Spine stereotactic radiosurgery (SSRS) is increasingly being used to treat metastatic spinal tumors and has shown high rates of local tumor control.
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Frequently Asked Questions
Introduction to spinal cord
What are the top hospitals conducting spinal cord research?
When it comes to pushing the boundaries of medical research in spinal cord treatments, several hospitals are leading the way. In Chicago, the Shirley Ryan AbilityLab is at the forefront with six ongoing clinical trials focused on spinal cord injuries. Known for its world-class rehabilitation services, this institution is driven by a commitment to helping patients regain their mobility and independence after such life-altering incidents.
Meanwhile, in West Orange, New jersey, the Kessler Foundation is making significant strides with five active spinal cord trials. As a renowned research center dedicated to improving quality of life for individuals with disabilities, their focus on understanding and treating spinal cord injuries showcases their dedication to advancing scientific knowledge.
Further south in sunny Miami, researchers at the University of Miami are working diligently on four active clinical trials targeting spinal cord conditions. Located near beautiful beaches and vibrant culture-rich neighborhoods that embody resilience and determination–qualities mirrored within each participant striving toward recovery from these challenging injuries
Not too far away in Ann Arbor lies another formidable player in this field: The University of Michigan. With four ongoing clinical trials devoted exclusively to studying spinal cord injuries under their belt; they demonstrate unwavering commitment towards enhancing treatment strategies aimed at restoring function and improving outcomes.
Lastly, Thomas Jefferson University located in Philadelphia joins these esteemed institutionswith its own setof four currentspinalcordclinicaltrials underway.As oneofthe oldestandmost prestigiousacademicmedicalcentersintheUnitedStates,it embodiesa richhistoryof innovationandadvancementin healthcare.Throughtheirresearcheffortsfocusedonspinalcordinjuries,TJUiscontributingtothepoolofknowledge,andhopesarehighthattheirfindingswilltranslateintobreakthroughtreatmentsforpatientsaroundtheworld.Diverseyetunitedinthecommonpurposeofbringinghopeandleadingchange,institutionslikethesefosteracultureoffearlesscuriosityandtenacitytocombatoneofthemostchallengingconditionsthatcandevastatepeople'slives.
Which are the best cities for spinal cord clinical trials?
When it comes to spinal cord clinical trials, several cities have emerged as frontrunners in research and development. Chicago, Illinois leads the pack with 12 active trials focused on advancements such as Acute Intermitted Hypoxia, Neurostimulation for respiratory function after spinal cord injury, and Enhanced Medical Rehabilitation (EMR). Houston, Texas is also a key player with 12 ongoing studies exploring treatments like MT-3921 and mindfulness meditation (MM). Miami, Florida follows closely behind with 9 active trials investigating Mindfulness Exercise Group and Paralyzed Veterans of America (PVA) Cardio-Metabolic Disease (CMD) Consumer Guide Group among others. Lastly, Philadelphia, Pennsylvania boasts 9 active trials examining innovations like Neuro-Spinal Scaffold and Augmented Blood Pressure. These cities offer individuals dealing with spinal cord injuries access to cutting-edge clinical trials that hold promise for improved care outcomes.
Which are the top treatments for spinal cord being explored in clinical trials?
Exciting advancements in spinal cord treatments are unfolding through dedicated clinical trials. One standout treatment being explored is stem cell therapy, which holds great promise for regenerating damaged nerve cells. Another innovative approach involves the use of electrical stimulation to activate and retrain the spinal cord, aiding in functional recovery. Additionally, gene therapies that target specific genetic mutations associated with spinal cord injuries are showing encouraging results. As researchers continue their relentless pursuit of breakthroughs, these top treatments offer hope for improved outcomes and quality of life for those affected by spinal cord conditions.
What are the most recent clinical trials for spinal cord?
Exciting advancements are being made in the realm of spinal cord research, with recent clinical trials offering potential breakthroughs for patients. One such trial is investigating NVG-291, an injection specifically developed for spinal cord treatment. Additionally, researchers are exploring the effectiveness of Clemastine Fumarate as a possible therapy option. Another groundbreaking study focuses on Gadoquatrane - an approved macrocyclic GBCA that shows promise in improving outcomes for those with spinal cord injuries. Furthermore, remote CMR and exercise interventions are being tested to enhance the management and rehabilitation of individuals with paraplegia caused by spinal cord conditions. These latest trials hold great promise in advancing our understanding and care for people affected by spinal cord issues.
What spinal cord clinical trials were recently completed?
Recently completed clinical trials focused on spinal cord treatments have made significant strides in advancing our understanding and potential therapies for this debilitating condition. Notably, the trial sponsored by Acorda Therapeutics investigated their promising therapy CVT-301 and concluded in February 2021. Similarly, a study led by Novartis Pharmaceuticals examined the efficacy of BAF312 and reached completion in November 2020. These milestones mark important achievements in the pursuit of improved treatments for spinal cord-related disorders, offering hope to patients seeking better outcomes and quality of life.