Popular Trials
Opioid Agonist
Long-acting Buprenorphine vs. Naltrexone for Opioid Use Disorder
Recruiting3 awardsPhase 4
New Haven, Connecticut
This trial will compare the effectiveness of two medications used to treat opioid use disorder, extended-release buprenorphine (XR-B) vs. extended-release naltrexone (XR-NTX), among adults currently incarcerated in U.S. jails and prisons.
Opioid Antagonist
Extended-Release Naltrexone + Buprenorphine for Cocaine Use Disorder
Recruiting0 awardsPhase 2
Los Angeles, California
This trial tests a combination of two medications, naltrexone and buprenorphine, for adults addicted to cocaine. Naltrexone blocks the high from cocaine, while buprenorphine helps reduce cravings and withdrawal symptoms. The goal is to see if this combination is more effective. Buprenorphine has been proposed as a treatment for cocaine abuse, and its combination with naltrexone has shown potential in reducing cocaine intake.
Popular Filters
Phase 3 Trials
Extended Release Buprenorphine for Opioid Use Disorder
Recruiting1 awardPhase 2 & 3
New Haven, Connecticut
This trial is testing whether a 28-day formulation of extended-release buprenorphine is more effective than usual treatment for patients with a moderate or severe opioid use disorder who are seen by an addiction consultation service and agree to start a medication for OUD.
Opioid Partial Agonist
Buprenorphine + XR-Naltrexone for Opioid Use Disorder
Recruiting0 awardsPhase 2 & 3
New York, New York
This trial will compare the effectiveness of a new drug combination to treating opioid addiction with extended release naltrexone alone. It is a double-blind, placebo-controlled study, meaning neither the participants nor the researchers will know who is receiving the new treatment or the placebo. The study will last 24 weeks, during which participants will receive six injections of either the new treatment or a placebo. The study's goal is to see if the new treatment can improve treatment retention, reduce opioid craving, and improve mood.
Trials With No Placebo
Partial Agonist
Pharmacotherapy Strategies for Opioid Use Disorder
Recruiting1 awardPhase 2
Little Rock, Arkansas
This trial will look at ways to improve treatment for people with opioid addiction, by testing different combinations of drugs and behavioral therapies. The goal is to find out which approaches are most likely to lead to long-term success and help people stay off opioids.
Extended Release Buprenorphine for Opioid Use Disorder
Recruiting1 awardPhase 2 & 3
New Haven, Connecticut
This trial is testing whether a 28-day formulation of extended-release buprenorphine is more effective than usual treatment for patients with a moderate or severe opioid use disorder who are seen by an addiction consultation service and agree to start a medication for OUD.
View More Related Trials
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.