Dr. Afshan Hameed, MD

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University of California Irvine Health

Studies Pregnancies
Studies Blood Thinners
2 reported clinical trials
6 drugs studied

Affiliated Hospitals

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University Of California Irvine Health

Clinical Trials Afshan Hameed, MD is currently running

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Bromocriptine

for Peripartum Cardiomyopathy

The study will enroll 200 women newly diagnosed with peripartum cardiomyopathy within 5 months postpartum in a randomized placebo controlled trial of bromocriptine therapy to evaluate its impact on myocardial recovery and clinical outcomes. Given that bromocriptine prevents breastfeeding, an additional 50 women with peripartum cardiomyopathy excluded from the trial due to a desire to continue breastfeeding but meeting all other entry criteria will be followed in an observational cohort.

Recruiting

2 awards

Phase 4

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Low Molecular Weight Heparin

for Blood Clot Prevention in Pregnancy

Pregnancy is associated with a increased risk of developing blood clots. There is nearly a 5 times greater risk of developing a blood clot in pregnancy. Lovenox is a medication that helps to prevent the body from developing clots. It is safe to use in pregnancy. Previous studies have demonstrated that despite recommendation of Lovenox, to prevent blood clots, the majority of patient's (70 to 90%) did not receive adequate levels of Lovenox at times throughout the day, which likely increases the risk of developing clots. The increase in blood volume and increase in kidney function that occurs in pregnancy may contribute to the inadequate levels. Currently the recommendation for pregnant and nonpregnant patients requiring Lovenox, is to calculate the daily dose of Lovenox and split the dose, giving half in the morning and the other half in the evening. This research study proposes that due to changes in the body during pregnancy that the daily Lovenox dosing be split into three times a day to achieve more consistent levels of Lovenox than twice a day in pregnant women.

Recruiting

5 awards

Phase 4

2 criteria

More about Afshan Hameed, MD

Clinical Trial Related

3 years of experience running clinical trials · Led 2 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Afshan Hameed, MD has experience with

  • Lovenox
  • Bromocriptine
  • Guideline Directed Medical Therapy For Heart Failure (GDMT)
  • Placebo
  • Rivaroxaban
  • Second Placebo

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