Dr. Aine E. Clements
Claim this profileOhioHealth Mansfield Hospital
Studies Ovarian Cancer
Studies Cancer
6 reported clinical trials
31 drugs studied
Area of expertise
1Ovarian Cancer
KRAS positive
Stage IV
NRAS positive
2Cancer
Stage I
Stage IV
KRAS positive
Affiliated Hospitals
Clinical Trials Aine E. Clements is currently running
Chemotherapy
for Cancer
This phase III trial studies how well active surveillance help doctors to monitor subjects with low risk germ cell tumors for recurrence after their tumor is removed. When the germ cell tumor has spread outside of the organ in which it developed, it is considered metastatic. Drugs used in chemotherapy, such as bleomycin, carboplatin, etoposide, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. The trial studies whether carboplatin or cisplatin is the preferred chemotherapy to use in treating metastatic standard risk germ cell tumors.
Recruiting2 awards Phase 326 criteria
Selumetinib + Olaparib
for Ovarian and Endometrial Cancer
This phase II ComboMATCH treatment trial compares selumetinib plus olaparib to selumetinib alone in women with endometrial or ovarian (fallopian tube and primary peritoneal) cancer that has come back (recurrent) or that remains despite treatment (persistent) and harbors a mutation in the RAS pathway. Selumetinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Olaparib is an inhibitor of PARP, an enzyme that helps repair deoxyribonucleic acid (DNA) when it becomes damaged. Blocking PARP may help keep tumor cells from repairing their damaged DNA, causing them to die. PARP inhibitors are a type of targeted therapy. The addition of olaparib to selumetinib could increase the percentage of tumors that shrink as well as lengthen the time that the tumors remain stable (without progression) as compared to selumetinib alone.
Recruiting1 award Phase 2
More about Aine E. Clements
Clinical Trial Related7 years of experience running clinical trials · Led 6 trials as a Principal Investigator · 5 Active Clinical TrialsTreatments Aine E. Clements has experience with
- Selumetinib Sulfate
- Binimetinib
- Palbociclib
- Olaparib
- Levonorgestrel-Releasing Intrauterine System
- Everolimus
Breakdown of trials Aine E. Clements has run
Ovarian Cancer
Cancer
Endometrial Cancer
Fallopian Tube Cancer
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Aine E. Clements specialize in?
Aine E. Clements focuses on Ovarian Cancer and Cancer. In particular, much of their work with Ovarian Cancer has involved KRAS positive patients, or patients who are Stage IV.
Is Aine E. Clements currently recruiting for clinical trials?
Yes, Aine E. Clements is currently recruiting for 5 clinical trials in Mansfield Ohio. If you're interested in participating, you should apply.
Are there any treatments that Aine E. Clements has studied deeply?
Yes, Aine E. Clements has studied treatments such as Selumetinib Sulfate, Binimetinib, Palbociclib.
What is the best way to schedule an appointment with Aine E. Clements?
Apply for one of the trials that Aine E. Clements is conducting.
What is the office address of Aine E. Clements?
The office of Aine E. Clements is located at: OhioHealth Mansfield Hospital, Mansfield, Ohio 44903 United States. This is the address for their practice at the OhioHealth Mansfield Hospital.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.