Dr. Anand Mahadevan
Claim this profileGeisinger Medical Center
Studies Cancer
Studies Glioblastoma
11 reported clinical trials
25 drugs studied
Area of expertise
1Cancer
Stage IV
Stage II
Stage III
2Glioblastoma
Affiliated Hospitals
Clinical Trials Anand Mahadevan is currently running
Stereotactic Radiosurgery vs. HA-WBRT + Memantine
for Brain Cancer
Stereotactic radiosurgery (SRS) is a commonly used treatment for brain tumors. It is a one-day (or in some cases two day), out-patient procedure during which a high dose of radiation is delivered to small spots in the brain while excluding the surrounding normal brain. Whole brain radiation therapy with hippocampal avoidance (HA-WBRT) is when radiation therapy is given to the whole brain, while trying to decrease the amount of radiation that is delivered to the area of the hippocampus. The hippocampus is a brain structure that is important for memory. Memantine is a drug that is given to help relieve symptoms that can be caused by WBRT, including problems with memory and other mental symptoms. Health Canada, the regulatory body that oversees the use of drugs in Canada, has not approved the sale or use of memantine in combination with WBRT to treat this kind of cancer, although they have allowed its use in this study.
Recruiting2 awards Phase 3
Whole Brain Radiotherapy + Stereotactic Radiosurgery
for Brain Metastasis
This phase III trial compares the effect of adding whole brain radiotherapy with hippocampal avoidance and memantine to stereotactic radiosurgery versus stereotactic radiosurgery alone in treating patients with cancer that has spread to the brain and come back in other areas of the brain after earlier stereotactic radiosurgery. Hippocampus avoidance during whole-brain radiation therapy decreases the amount of radiation that is delivered to the hippocampus, which is a brain structure that is important for memory. The medicine memantine is also often given with whole brain radiation therapy because it may decrease the risk of side effects of radiation on thinking and memory. Stereotactic radiosurgery delivers a high dose of radiation only to the small areas of cancer in the brain and avoids the surrounding normal brain tissue. Adding whole brain radiotherapy with hippocampal avoidance and memantine to stereotactic radiosurgery may be effective in shrinking or stabilizing cancer that has spread to the brain and returned in other areas of the brain after receiving stereotactic radiosurgery.
Recruiting2 awards Phase 312 criteria
More about Anand Mahadevan
Clinical Trial Related5 years of experience running clinical trials · Led 11 trials as a Principal Investigator · 5 Active Clinical TrialsTreatments Anand Mahadevan has experience with
- Memantine
- Stereotactic Radiosurgery
- Whole-Brain Radiotherapy
- Optune®
- Cisplatin
- Fluorouracil
Breakdown of trials Anand Mahadevan has run
Cancer
Glioblastoma
Brain Tumor
Lung Cancer
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Anand Mahadevan specialize in?
Anand Mahadevan focuses on Cancer and Glioblastoma. In particular, much of their work with Cancer has involved Stage IV patients, or patients who are Stage II.
Is Anand Mahadevan currently recruiting for clinical trials?
Yes, Anand Mahadevan is currently recruiting for 5 clinical trials in Danville Pennsylvania. If you're interested in participating, you should apply.
Are there any treatments that Anand Mahadevan has studied deeply?
Yes, Anand Mahadevan has studied treatments such as Memantine, Stereotactic Radiosurgery, Whole-Brain Radiotherapy.
What is the best way to schedule an appointment with Anand Mahadevan?
Apply for one of the trials that Anand Mahadevan is conducting.
What is the office address of Anand Mahadevan?
The office of Anand Mahadevan is located at: Geisinger Medical Center, Danville, Pennsylvania 17822 United States. This is the address for their practice at the Geisinger Medical Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.