Dr. Bogdan S. Eftimie
Claim this profileWashington Hospital
Studies Cancer
Studies Breast Cancer
11 reported clinical trials
35 drugs studied
Area of expertise
1Cancer
Stage IV
HER2 positive
ER positive
2Breast Cancer
HER2 positive
ER positive
ER negative
Affiliated Hospitals
Clinical Trials Bogdan S. Eftimie is currently running
Osimertinib + Bevacizumab
for Lung Cancer
This phase III trial compares the effect of bevacizumab and osimertinib combination vs. osimertinib alone for the treatment of non-small cell lung cancer that has spread outside of the lungs (stage IIIB-IV) and has a change (mutation) in a gene called EGFR. The EGFR protein is involved in cell signaling pathways that control cell division and survival. Sometimes, mutations in the EGFR gene cause EGFR proteins to be made in higher than normal amounts on some types of cancer cells. This causes cancer cells to divide more rapidly. Osimertinib may stop the growth of tumor cells by blocking EGFR that is needed for cell growth in this type of cancer. Monoclonal antibodies, such as bevacizumab, may interfere with the ability of tumor cells to grow and spread. Giving osimertinib with bevacizumab may control cancer for longer and help patients live longer as compared to osimertinib alone.
Recruiting2 awards Phase 331 criteria
Chemotherapy Reduction After Surgery
for Breast Cancer
This trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Drugs used in chemotherapy, such as paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Trastuzumab and pertuzumab are both a form of "targeted therapy" because they work by attaching themselves to specific molecules (receptors) on the surface of tumor cells, known as HER2 receptors. When these drugs attach to HER2 receptors, the signals that tell the cells to grow are blocked and the tumor cell may be marked for destruction by the body's immune system. Giving paclitaxel, trastuzumab, and pertuzumab may enable fewer chemotherapy drugs to be given without compromising patient outcomes compared to the usual treatment.
Recruiting1 award Phase 227 criteria
More about Bogdan S. Eftimie
Clinical Trial Related3 years of experience running clinical trials · Led 11 trials as a Principal Investigator · 8 Active Clinical TrialsTreatments Bogdan S. Eftimie has experience with
- Paclitaxel
- Trastuzumab
- Pertuzumab
- Duloxetine
- Atezolizumab
- Bevacizumab
Breakdown of trials Bogdan S. Eftimie has run
Cancer
Breast Cancer
Lung Cancer
Non-Small Cell Lung Cancer
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Bogdan S. Eftimie specialize in?
Bogdan S. Eftimie focuses on Cancer and Breast Cancer. In particular, much of their work with Cancer has involved Stage IV patients, or patients who are HER2 positive.
Is Bogdan S. Eftimie currently recruiting for clinical trials?
Yes, Bogdan S. Eftimie is currently recruiting for 8 clinical trials in Fremont California. If you're interested in participating, you should apply.
Are there any treatments that Bogdan S. Eftimie has studied deeply?
Yes, Bogdan S. Eftimie has studied treatments such as Paclitaxel, Trastuzumab, Pertuzumab.
What is the best way to schedule an appointment with Bogdan S. Eftimie?
Apply for one of the trials that Bogdan S. Eftimie is conducting.
What is the office address of Bogdan S. Eftimie?
The office of Bogdan S. Eftimie is located at: Washington Hospital, Fremont, California 94538 United States. This is the address for their practice at the Washington Hospital.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.