Dr. Brenda Law, MD
Claim this profileGovernors of University of Alberta
Studies Premature Birth
Studies Bleeding
3 reported clinical trials
7 drugs studied
Affiliated Hospitals
Clinical Trials Brenda Law, MD is currently running
Delayed Cord Clamping Techniques
for Newborns with Congenital Heart Disease
The goal of this clinical trial is to compare 2 different timepoints for clamping the umbilical cord at birth for term-born infants with a prenatal diagnosis of congenital heart disease (CHD). The main questions it aims to answer are: * Does Delayed Cord Clamping at 120 seconds (DCC-120) or Delayed Cord Clamping at 30 seconds (DCC-30) after birth lead to better health outcomes? * Does DCC-120 seconds or DCC-30 seconds after birth lead to better neuromotor outcomes at 22-26 months of infant age (postnatal)? Participants will be asked to do the following: * Participate in either DCC-120 or DCC-30 at birth (randomized assignment). * Complete General Movements Assessment (GMA) at 3-4 months of infant age (postnatal), complete questionnaires / surveys at this time. * Complete questionnaires / surveys at 9-12 months of infant age (postnatal). * Complete Hammersmith Infant Neurological Examination (HINE), Developmental Assessment of Young Children 2 Edition (DAYC-2), and questionnaires / surveys at 22-26 months of infant age (postnatal). * Permit data collection from electronic medical records for both the mother and infant study participants. Investigators will compare DCC-120 vs. DCC-30 to see which approach is more beneficial to both the mother and baby with CHD.
Recruiting1 award N/A4 criteria
Doxapram
for Breathing Problems in Preterm Infants
Preterm infants often suffer from apnea of prematurity (AOP; a cessation of breathing) due to immaturity of the respiratory system. AOP can lead to oxygen shortage and a low heart rate which might harm the development of the newborn, especially the central nervous system. In order to prevent oxygen shortage, infants are treated with non-invasive respiratory support and caffeine. Despite these treatments, many preterm newborns still suffer from AOP and need invasive mechanical ventilation. Although this will result in complete resolution of AOP, invasive mechanical ventilation has the disadvantage of being a major risk of chronic lung disease and impaired neurodevelopmental outcome. Restrictive invasive ventilation is therefore advocated nowadays in preterm infants. Doxapram is a respiratory stimulant that has been administered off-label to treat AOP. Doxapram, as add-on treatment, seems to be effective in treating AOP and to prevent invasive mechanical ventilation. It is unclear if a preterm infant benefit from doxapram treatment on the longer term. This study compares doxapram to placebo and hypothesizes that doxapram will protect preterm infants from both invasive ventilation (and related lung disease) and AOP related oxygen shortage (and related impaired brain development).
Recruiting1 award Phase 3
More about Brenda Law, MD
Clinical Trial Related1 year of experience running clinical trials · Led 3 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Brenda Law, MD has experience with
- Umbilical Cord Milking UCM
- Delayed Cord Clamping DCC
- Umbilical Cord Clamping At ~30 Seconds
- Umbilical Cord Clamping At ~120 Seconds
- Umbilical Cord Milking
- Doxapram
Breakdown of trials Brenda Law, MD has run
Neonatal Intraventricular Hemorrhage
Congenital Heart Defects
Other Doctors you might be interested in
Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Brenda Law, MD specialize in?
Brenda Law, MD focuses on Premature Birth and Bleeding. In particular, much of their work with Premature Birth has involved treating patients, or patients who are undergoing treatment.
Is Brenda Law, MD currently recruiting for clinical trials?
Yes, Brenda Law, MD is currently recruiting for 2 clinical trials in Edmonton Alberta. If you're interested in participating, you should apply.
Are there any treatments that Brenda Law, MD has studied deeply?
Yes, Brenda Law, MD has studied treatments such as Umbilical cord milking UCM, Delayed cord clamping DCC, Umbilical Cord Clamping at ~30 seconds.
What is the best way to schedule an appointment with Brenda Law, MD?
Apply for one of the trials that Brenda Law, MD is conducting.
What is the office address of Brenda Law, MD?
The office of Brenda Law, MD is located at: Governors of University of Alberta, Edmonton, Alberta T6G 2R3 Canada. This is the address for their practice at the Governors of University of Alberta.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.