Dr. Craig Brown, MD

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St-John Regional Hospital

Studies Acute Kidney Injury
Studies Coronary Artery Disease
2 reported clinical trials
3 drugs studied

Affiliated Hospitals

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St. John Regional Hospital
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Horizon Health Network, Saint John Regional Hospital

Clinical Trials Craig Brown, MD is currently running

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Single vs Multiple Arterial Grafts

for Heart Disease

The central hypothesis of ROMA:Women is that the use of multiple arterial grafting (MAG) will improve clinical outcomes and quality of life (QOL) compared to single arterial grfating (SAG). The specific aims of ROMA:Women are: Aim 1: Determine the impact of MAG vs SAG on major adverse cardiac and cerebrovascular events in women undergoing coronary artery bypass grfating (CABG). The investigators will compare major adverse cardiac and cerebrovascular events (death, stroke, non-procedural myocardial infarction, repeat revascularization, and hospital readmission for acute coronary syndrome or heart failure) in a cohort of 2,000 women randomized 1:1 to MAG or SAG (690 from the parent ROMA trial + 1,310 from ROMA:Women). Differences by important clinical and surgical subgroups (patients younger or older than 70 years, diabetics, racial and ethnic minorities, on vs off pump CABG, type of arterial grafts used) will also be evaluated. The women enrolled in the ongoing ROMA trial (anticipated to be approximately 690) will be included in ROMA:Women, increasing efficiency and reducing enrollment time. Hypothesis 1.0. MAG will reduce the incidence of major adverse cardiac and cerebrovascular events. Hypothesis 1.1. The improvement with MAG will be consistent across key subgroups. Aim 2: Determine the impact of MAG vs SAG on generic and disease-specific QOL, physical and mental health symptoms in women undergoing CABG. The investigators will compare generic (SF-12, EQ-5D) and disease-specific (Seattle Angina Questionnaire) QOL and physical and mental health symptoms (PROMIS-29) in a sub-cohort of 500 women randomized 1:1 to MAG or SAG (including those enrolled in ROMA:QOL). Differences by important subgroups (as defined above) will also be evaluated. Hypothesis 2.0. MAG will improve generic and disease-specific QOL compared to SAG. Hypothesis 2.1. MAG will improve physical and mental health symptoms compared to SAG. Hypothesis 2.2. The improvement with MAG will be consistent across key subgroups.
Recruiting1 award N/A4 criteria

More about Craig Brown, MD

Clinical Trial Related1 year of experience running clinical trials · Led 2 trials as a Principal Investigator · 1 Active Clinical Trial
Treatments Craig Brown, MD has experience with
  • RBT-1
  • Multiple Arterial Grafting
  • Single Arterial Graft
Breakdown of trials Craig Brown, MD has run
Acute Kidney Injury
Coronary Artery Disease
Heart Disease
Coronary Artery Bypass Surgery

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Frequently asked questions

Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Craig Brown, MD specialize in?
Craig Brown, MD focuses on Acute Kidney Injury and Coronary Artery Disease. In particular, much of their work with Acute Kidney Injury has involved treating patients, or patients who are undergoing treatment.
Is Craig Brown, MD currently recruiting for clinical trials?
Yes, Craig Brown, MD is currently recruiting for 1 clinical trial in Saint John New Brunswick. If you're interested in participating, you should apply.
Are there any treatments that Craig Brown, MD has studied deeply?
Yes, Craig Brown, MD has studied treatments such as RBT-1, Multiple arterial grafting, Single arterial graft.
What is the best way to schedule an appointment with Craig Brown, MD?
Apply for one of the trials that Craig Brown, MD is conducting.
What is the office address of Craig Brown, MD?
The office of Craig Brown, MD is located at: St-John Regional Hospital, Saint John, New Brunswick E2L 4L2 Canada. This is the address for their practice at the St-John Regional Hospital.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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