David Einspahr, M.D. - Stormont Vail Health

Dr. David E. Einspahr

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Cotton O'Neil Cancer Center / Stormont Vail Health

Studies Lung Cancer
Studies Non-Small Cell Lung Cancer
9 reported clinical trials
31 drugs studied

Area of expertise

1

Lung Cancer

David E. Einspahr has run 4 trials for Lung Cancer. Some of their research focus areas include:

Stage II
Stage I
Stage III
2

Non-Small Cell Lung Cancer

David E. Einspahr has run 3 trials for Non-Small Cell Lung Cancer. Some of their research focus areas include:

Stage II
Stage III
Stage I

Affiliated Hospitals

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Cotton O'Neil Cancer Center / Stormont Vail Health

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Cotton O'Neil Cancer Center (Stormont-Vail Cancer Center)

Clinical Trials David E. Einspahr is currently running

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Immunotherapy + Chemotherapy

for Non-Small Cell Lung Cancer

This phase III ALCHEMIST treatment trial tests the addition of pembrolizumab to usual chemotherapy for the treatment of stage IIA, IIB, IIIA or IIIB non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs, such as cisplatin, pemetrexed, carboplatin, gemcitabine hydrochloride, and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving pembrolizumab with usual chemotherapy may help increase survival times in patients with stage IIA, IIB, IIIA or IIIB non-small cell lung cancer.

Recruiting

2 awards

Phase 3

27 criteria

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Hormone Therapy + Radiation

for Prostate Cancer

This phase III trial uses the Decipher risk score to guide therapy selection. Decipher score is based on the activity of 22 genes in prostate tumor and may predict how likely it is for recurrent prostate cancer to spread (metastasize) to other parts of the body. Decipher score in this study is used for patient selection and the two variations of treatment to be studied: intensification for higher Decipher score or de-intensification for low Decipher score. Patients with higher Decipher risk score will be assigned to the part of the study that compares the use of 6 months of the usual treatment (hormone therapy and radiation treatment) to the use of darolutamide plus the usual treatment (intensification). The purpose of this section of the study is to determine whether the additional drug can reduce the chance of cancer coming back and spreading in patients with higher Decipher score. The addition of darolutamide to the usual treatment may better control the cancer and prevent it from spreading. Alternatively, patients with low Decipher risk score will be assigned to the part of the study that compares the use of radiation treatment alone (de-intensification) to the usual approach (6 months of hormone therapy plus radiation). The purpose of this part of the study is to determine if radiation treatment alone is as effective compared to the usual treatment without affecting the chance of tumor coming back in patients with low Decipher score prostate cancer. Radiation therapy uses high energy to kill tumor cells and reduce the tumor size. Hormone therapy drugs such as darolutamide suppress or block the production or action of male hormones that play role in prostate cancer development. Effect of radiation treatment alone in patients with low Decipher score prostate cancer could be the same as the usual approach in stabilizing prostate cancer and preventing it from spreading, while avoiding the side effects associated with hormonal therapy.

Recruiting

2 awards

Phase 3

1 criteria

More about David E. Einspahr

Clinical Trial Related

6 years of experience running clinical trials · Led 9 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments David E. Einspahr has experience with

  • Carboplatin
  • Paclitaxel
  • Pembrolizumab
  • Pemetrexed Disodium
  • Gemcitabine Hydrochloride
  • Gemcitabine

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