Dr. Debora S. Bruno
Claim this profileCase Western Reserve University
Studies Lung Cancer
Studies Non-Small Cell Lung Cancer
9 reported clinical trials
19 drugs studied
Area of expertise
1Lung Cancer
Stage IV
Stage III
EGFR positive
2Non-Small Cell Lung Cancer
Stage IV
Stage III
EGFR positive
Affiliated Hospitals
Clinical Trials Debora S. Bruno is currently running
Osimertinib + Bevacizumab
for Lung Cancer
This phase III trial compares the effect of bevacizumab and osimertinib combination vs. osimertinib alone for the treatment of non-small cell lung cancer that has spread outside of the lungs (stage IIIB-IV) and has a change (mutation) in a gene called EGFR. The EGFR protein is involved in cell signaling pathways that control cell division and survival. Sometimes, mutations in the EGFR gene cause EGFR proteins to be made in higher than normal amounts on some types of cancer cells. This causes cancer cells to divide more rapidly. Osimertinib may stop the growth of tumor cells by blocking EGFR that is needed for cell growth in this type of cancer. Monoclonal antibodies, such as bevacizumab, may interfere with the ability of tumor cells to grow and spread. Giving osimertinib with bevacizumab may control cancer for longer and help patients live longer as compared to osimertinib alone.
Recruiting2 awards Phase 331 criteria
Genetic Testing
for Early-Stage Lung Cancer
This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.
Recruiting0 awards N/A4 criteria
More about Debora S. Bruno
Clinical Trial Related3 years of experience running clinical trials · Led 9 trials as a Principal Investigator · 7 Active Clinical TrialsTreatments Debora S. Bruno has experience with
- Bevacizumab
- Nivolumab
- Pembrolizumab
- Osimertinib
- Pemetrexed
- Educational Intervention
Breakdown of trials Debora S. Bruno has run
Lung Cancer
Non-Small Cell Lung Cancer
Cancer
Educational Intervention
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Debora S. Bruno specialize in?
Debora S. Bruno focuses on Lung Cancer and Non-Small Cell Lung Cancer. In particular, much of their work with Lung Cancer has involved Stage IV patients, or patients who are Stage III.
Is Debora S. Bruno currently recruiting for clinical trials?
Yes, Debora S. Bruno is currently recruiting for 7 clinical trials in Cleveland Ohio. If you're interested in participating, you should apply.
Are there any treatments that Debora S. Bruno has studied deeply?
Yes, Debora S. Bruno has studied treatments such as Bevacizumab, Nivolumab, Pembrolizumab.
What is the best way to schedule an appointment with Debora S. Bruno?
Apply for one of the trials that Debora S. Bruno is conducting.
What is the office address of Debora S. Bruno?
The office of Debora S. Bruno is located at: Case Western Reserve University, Cleveland, Ohio 44106 United States. This is the address for their practice at the Case Western Reserve University.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.