Deborah J. Wong, MD, PhD - Head and ...

Dr. Deborah Wong, MD, PhD

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UCLA / Jonsson Comprehensive Cancer Center

Studies Pancreatic Cancer
Studies Squamous Cell Carcinoma
7 reported clinical trials
8 drugs studied

Area of expertise

1

Pancreatic Cancer

Deborah Wong, MD, PhD has run 4 trials for Pancreatic Cancer. Some of their research focus areas include:

Stage IV
Stage III
PD-L1 positive
2

Squamous Cell Carcinoma

Deborah Wong, MD, PhD has run 3 trials for Squamous Cell Carcinoma. Some of their research focus areas include:

Stage IV
Stage III
PD-L1 positive

Affiliated Hospitals

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University Of California Los Angeles (UCLA)

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UCLA / Jonsson Comprehensive Cancer Center

Clinical Trials Deborah Wong, MD, PhD is currently running

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TAB004 + Toripalimab

for Solid Cancers

The primary objective is to assess the safety and tolerability of TAB004 as monotherapy and in combination with toripalimab in subjects with selected advanced solid malignancies, including lymphoma, and to evaluate the recommended Phase 2 dose. The secondary objectives are to: 1) describe the pharmacokinetic (PK) profile of TAB004 monotherapy and in combination with toripalimab and to describe the PK profile of toripalimab when administered with TAB004, 2) evaluate antitumor activity of TAB004 monotherapy and in combination with toripalimab; and 3) determine the immunogenicity of TAB004 monotherapy and in combination with toripalimab and to determine the immunogenicity of toripalimab when administered with TAB004. The exploratory objectives are to: 1) evaluate pharmacodynamic effects of TAB004 on its target receptor BTLA, as well as effects on the immune system; 2) evaluate biomarkers that may correlate with activity of TAB004 as monotherapy and in combination with toripalimab; 3) evaluate the utility of BTLA ligand, herpesvirus-entry mediator (HVEM), and additional exploratory biomarkers that could aid in selection of appropriate subjects for TAB004 monotherapy and in combination with toripalimab.

Recruiting

1 award

Phase 1

10 criteria

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Pembrolizumab

for Leukoplakia

This trial studies how well pembrolizumab works in treating leukoplakia. Pembrolizumab helps the immune system fight cancer by blocking a protein that prevents immune cells from attacking cancer cells. The trial targets patients with leukoplakia, aiming to see if this medication can effectively treat this condition. Pembrolizumab is an immune checkpoint inhibitor that has been used in the treatment of various cancers, including non-small cell lung cancer, melanoma, and head and neck cancers.

Recruiting

1 award

Phase 2

More about Deborah Wong, MD, PhD

Clinical Trial Related

6 years of experience running clinical trials · Led 7 trials as a Principal Investigator · 3 Active Clinical Trials

Treatments Deborah Wong, MD, PhD has experience with

  • Pembrolizumab
  • Cetuximab
  • FS118
  • TAB004
  • Toripalimab
  • Rivoceranib

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