Dr. Elizabeth Brem, MD
Claim this profileUC Irvine Health/Chao Family Comprehensive Cancer Center
Studies Cancer
Studies Lymphoma
10 reported clinical trials
24 drugs studied
Area of expertise
1Cancer
Stage IV
Stage III
13q positive
2Lymphoma
13q positive
13q negative
12 positive
Affiliated Hospitals
Clinical Trials Elizabeth Brem, MD is currently running
Rituximab vs Mosunetuzumab
for Follicular Lymphoma
This phase III trial compares the effectiveness of rituximab to mosunetuzumab in treating patients with follicular lymphoma with a low tumor burden. Rituximab is a monoclonal antibody. It binds to a protein called CD20, which is found on B cells (a type of white blood cell) and some types of cancer cells. This may help the immune system kill cancer cells. Mosunetuzumab is a monoclonal antibody that may interfere with the ability of cancer cells to grow and spread. It is not yet known if giving rituximab or mosunetuzumab works better in treating patients with follicular lymphoma with a low tumor burden.
Recruiting2 awards Phase 313 criteria
Oral Azacitidine + R-miniCHOP
for Diffuse Large B-Cell Lymphoma
This phase II/III trial compares the side effects and activity of oral azacitidine in combination with the standard drug therapy (reduced dose rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisone \[R-miniCHOP\]) versus R-miniCHOP alone in treating patients 75 years or older with newly diagnosed diffuse large B cell lymphoma. R-miniCHOP includes a monoclonal antibody (a type of protein), called rituximab, which attaches to the lymphoma cells and may help the immune system kill these cells. R-miniCHOP also includes prednisone which is an anti-inflammatory medication and a combination of 3 chemotherapy drugs, cyclophosphamide, doxorubicin, and vincristine. These 3 chemotherapy drugs, as well as oral azacitidine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Combining oral azacitidine with R-miniCHOP may shrink the cancer or extend the time without disease symptoms coming back or extend patient's survival when compared to R-miniCHOP alone.
Recruiting1 award Phase 2 & 314 criteria
More about Elizabeth Brem, MD
Clinical Trial Related5 years of experience running clinical trials · Led 10 trials as a Principal Investigator · 6 Active Clinical TrialsTreatments Elizabeth Brem, MD has experience with
- Rituximab
- Cyclophosphamide
- Nivolumab
- Venetoclax
- Vincristine Sulfate
- Doxorubicin Hydrochloride
Breakdown of trials Elizabeth Brem, MD has run
Cancer
Lymphoma
B-Cell Lymphoma
Diffuse Large B-Cell Lymphoma
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Elizabeth Brem, MD specialize in?
Elizabeth Brem, MD focuses on Cancer and Lymphoma. In particular, much of their work with Cancer has involved Stage IV patients, or patients who are Stage III.
Is Elizabeth Brem, MD currently recruiting for clinical trials?
Yes, Elizabeth Brem, MD is currently recruiting for 6 clinical trials in Orange California. If you're interested in participating, you should apply.
Are there any treatments that Elizabeth Brem, MD has studied deeply?
Yes, Elizabeth Brem, MD has studied treatments such as Rituximab, Cyclophosphamide, Nivolumab.
What is the best way to schedule an appointment with Elizabeth Brem, MD?
Apply for one of the trials that Elizabeth Brem, MD is conducting.
What is the office address of Elizabeth Brem, MD?
The office of Elizabeth Brem, MD is located at: UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California 92868 United States. This is the address for their practice at the UC Irvine Health/Chao Family Comprehensive Cancer Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.