Hamid Emamekhoo | Department of ...

Dr. Hamid Emamekhoo, MD

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University of Wisconsin Carbone Cancer Center

Studies Prostate Cancer
Studies Lung Cancer
11 reported clinical trials
21 drugs studied

Area of expertise

1

Prostate Cancer

Hamid Emamekhoo, MD has run 7 trials for Prostate Cancer. Some of their research focus areas include:

Stage IV
DDRD negative
MMR-d positive
2

Lung Cancer

Hamid Emamekhoo, MD has run 3 trials for Lung Cancer. Some of their research focus areas include:

Stage IV
BRAF positive
MSI-H positive

Affiliated Hospitals

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University Of Wisconsin - Carbone Cancer Center

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University Of Wisconsin

Clinical Trials Hamid Emamekhoo, MD is currently running

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Registry

for Advanced Prostate Cancer

Our intent is to establish the International Registry to Improve Outcomes in Men with Advanced Prostate Cancer (IRONMAN) as a prospective, international cohort of minimum 5,000 men with advanced cancer, including men with mHSPC and M0/M1 CRPC. The goal is to establish a population-based registry and recruit patients across academic and community practices from Australia, Barbados, Brazil, Canada, Ireland, Jamaica, Kenya, Nigeria, Norway, Spain, South Africa, Sweden, Switzerland, the United Kingdom (UK), and the United States (US). Target accrual number and number of participating sites are subject to change based on accrual, funding, and interest in participation by other international sites. This cohort study will facilitate a better understanding of the variation in care and treatment of advanced prostate cancer across countries and across academia and community based practices. Detailed data will be collected from patients at study enrollment and then during follow-up, for a minimum of five years. Patients will be followed prospectively for overall survival, clinically significant adverse events, comorbidities, changes in cancer treatments, and PROMs. PROMs questionnaires will be collected at enrollment and every three months thereafter. Physician Questionnaires will be collected from all participating sites at patient enrollment, time of first change in treatment and/or one year follow-up, at each subsequent change of treatment, and discontinuation of treatment. As such, this registry will help identify the treatment sequences or combinations that optimize overall survival and PROMs for men with mHSPC and M0/M1 CRPC. By collecting blood at enrollment, time of first change in treatment and/or one year follow-up (plasma, cell free DNA, buffy coat / RNA), this registry will further identify and validate molecular phenotypes of disease that predict response and resistance to specific therapeutics. Additionally, every effort will be made to collect blood specimen at each subsequent change in treatment due to progression of disease. When feasible, existing tumor tissue may be collected for correlation with described blood based studies. All samples will be used for future research. This cohort study will provide the research community with a unique biorepository to identify biomarkers of treatment response and resistance.

Recruiting

1 award

N/A

5 criteria

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Stereotactic Radiation + Immunotherapy

for Kidney Cancer

This phase II trial tests whether the addition of radiation to the primary tumor, typically given with stereotactic ablative radiation therapy (SABR), in combination with standard of care immunotherapy improves outcomes in patients with renal cell cancer that is not recommended for surgery and has spread from where it first started (primary site) to other places in the body (metastatic). Radiation therapy uses high energy photons to kill tumor cells and shrink tumors. Stereotactic body radiation therapy uses special equipment to position a patient and deliver radiation to tumors with high precision. This method may kill tumor cells with fewer doses of radiation over a shorter period and cause less damage to normal tissue. Immunotherapy with monoclonal antibodies, such as nivolumab, ipilimumab, avelumab, and pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Axitinib, cabozantinib, and lenvatinib are in a class of medications called antiangiogenic agents. They work by stopping the formation of blood vessels that bring oxygen and nutrients to tumor. This may slow the growth and spread of tumor. Giving SABR in combination with standard of care immunotherapy may help shrink or stabilize the cancer in patients with renal cell cancer.

Recruiting

1 award

Phase 2

21 criteria

More about Hamid Emamekhoo, MD

Clinical Trial Related

8 years of experience running clinical trials · Led 11 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Hamid Emamekhoo, MD has experience with

  • Nivolumab
  • Ipilimumab
  • Cabozantinib
  • PTVG-HP
  • Docetaxel
  • Androgen Deprivation Therapy

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