Dr. Hope Cottrill
Claim this profileBaptist Health Lexington
Area of expertise
Ovarian Cancer
Hope Cottrill has run 5 trials for Ovarian Cancer. Some of their research focus areas include:
Uterine Cancer
Hope Cottrill has run 5 trials for Uterine Cancer. Some of their research focus areas include:
Affiliated Hospitals
Baptist Health Lexington
Baptist Health Louisville
Clinical Trials Hope Cottrill is currently running
Mirvetuximab + Bevacizumab
for Ovarian Cancer
GLORIOSA is a Phase 3 multicenter, open label study designed to evaluate the safety and efficacy of mirvetuximab Soravtansine + Bevacizumab as maintenance therapy in participants with platinum-sensitive ovarian, primary peritoneal or fallopian tube cancers with high folate receptor-alpha (FRα) expression.
Recruiting
2 awards
Phase 3
Herceptin Hylecta or Phesgo + Chemotherapy
for Uterine Cancer
This phase III trial tests whether adding trastuzumab and hyaluronidase-oysk (Herceptin Hylecta \[TM\]) or pertuzumab, trastuzumab and hyaluronidase-zzxf (Phesgo \[TM\]) to the usual chemotherapy (paclitaxel and carboplatin) works to shrink tumors in patients with HER2 positive endometrial cancer. Trastuzumab and pertuzumab are monoclonal antibodies and forms of targeted therapy that attach to specific molecules (receptors) on the surface of tumor cells, known as HER2 receptors. When trastuzumab or pertuzumab attach to HER2 receptors, the signals that tell the cells to grow are blocked and the tumor cell may be marked for destruction by the body's immune system. Hyaluronidase is an endoglycosidase. It helps to keep pertuzumab and trastuzumab in the body longer, so that these medications will have a greater effect. Hyaluronidase also allows trastuzumab and trastuzumab/pertuzumab to be given by injection under the skin and shortens their administration time compared to trastuzumab or pertuzumab alone. Paclitaxel is a taxane and in a class of medications called antimicrotubule agents. It stops tumor cells from growing and dividing and may kill them. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Giving Herceptin Hylecta or Phesgo in combination with paclitaxel and carboplatin may shrink the tumor and prevent the cancer from coming back in patients with HER2 positive endometrial cancer.
Recruiting
2 awards
Phase 3
More about Hope Cottrill
Clinical Trial Related
2 years of experience running clinical trials · Led 9 trials as a Principal Investigator · 3 Active Clinical Trials
Treatments Hope Cottrill has experience with
- Carboplatin
- Paclitaxel
- Bevacizumab
- Olaparib
- Topotecan
- AL3818
Breakdown of trials Hope Cottrill has run
Ovarian Cancer
Uterine Cancer
Fallopian Tube Cancer
Endometrial Adenocarcinoma
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Hope Cottrill specialize in?
Hope Cottrill focuses on Ovarian Cancer and Uterine Cancer. In particular, much of their work with Ovarian Cancer has involved Stage IV patients, or patients who are BRCA1 positive.
Is Hope Cottrill currently recruiting for clinical trials?
Yes, Hope Cottrill is currently recruiting for 3 clinical trials in Lexington Kentucky. If you're interested in participating, you should apply.
Are there any treatments that Hope Cottrill has studied deeply?
Yes, Hope Cottrill has studied treatments such as Carboplatin, Paclitaxel, Bevacizumab.
What is the best way to schedule an appointment with Hope Cottrill?
Apply for one of the trials that Hope Cottrill is conducting.
What is the office address of Hope Cottrill?
The office of Hope Cottrill is located at: Baptist Health Lexington, Lexington, Kentucky 40503 United States. This is the address for their practice at the Baptist Health Lexington.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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