Dr. Issa F. Khouri
Claim this profileM D Anderson Cancer Center
Studies Cancer
Studies T-Lymphoblastic Leukemia/Lymphoma
2 reported clinical trials
4 drugs studied
Affiliated Hospitals
Clinical Trials Issa F. Khouri is currently running
Inotuzumab Ozogamicin + Chemotherapy
for Leukemia or Lymphoma
The goal of this phase II clinical study is to learn about the safety of inotuzumab ozogamicin when given with fludarabine, with or without bendamustine, melphalan, and rituximab before and after a stem cell transplant. Researchers also want to learn if inotuzumab ozogamicin when given after a stem cell transplant can help control leukemia and lymphoma. Inotuzumab ozogamicin is a monoclonal antibody, called inotuzumab, linked to a chemotherapy drug called ozogamicin. Inotuzumab attaches to CD22-positive cancer cells in a targeted way and delivers ozogamicin to kill them. Giving chemotherapy before a bone marrow or peripheral blood stem cell transplant helps stop the growth of cells in the bone marrow, including normal blood-forming cells (stem cells) and cancer cells. Sometimes the transplanted cells from a donor attack the body's normal cells (called graft-versus-host disease). Giving tacrolimus and filgrastim before or after the transplant may stop this from happening. Fludarabine, bendamustine, melphalan, and rituximab are commonly given before stem cell transplants. Giving inotuzumab ozogamicin with chemotherapy may work better in treating patients with leukemia or lymphoma undergoing stem cell transplantation.
Recruiting1 award Phase 211 criteria
Bendamustine +/- Cyclophosphamide to Prevent GVHD Post Stem Cell Transplant
for Blood Cancers
This phase I/II trial studies the side effects and best dose of bendamustine when given with or without cyclophosphamide in preventing graft versus host disease (GVHD) in patients undergoing stem cell transplant. Drugs used in chemotherapy, such as bendamustine and cyclophosphamide, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving chemotherapy and total body irradiation before or after a stem cell transplant helps kills cancer cells that are in the body and helps make room in the patient's bone marrow for new blood-forming cells (stem cells) to grow. Sometimes, the transplanted cells from a donor can attack the body's normal cells called GVHD. Giving tacrolimus, mycophenolate mofetil, and filgrastim after the transplant may stop this from happening.
Recruiting1 award Phase 1 & 210 criteria
More about Issa F. Khouri
Clinical Trial Related5 years of experience running clinical trials · Led 2 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Issa F. Khouri has experience with
- Bendamustine
- Inotuzumab Ozogamicin
- Melphalan
- Cyclophosphamide
Breakdown of trials Issa F. Khouri has run
Cancer
T-Lymphoblastic Leukemia/Lymphoma
Acute Lymphoblastic Leukemia
Lymphoid Leukemia
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Issa F. Khouri specialize in?
Issa F. Khouri focuses on Cancer and T-Lymphoblastic Leukemia/Lymphoma. In particular, much of their work with Cancer has involved CD22 positive patients, or patients who are undergoing treatment.
Is Issa F. Khouri currently recruiting for clinical trials?
Yes, Issa F. Khouri is currently recruiting for 2 clinical trials in Houston Texas. If you're interested in participating, you should apply.
Are there any treatments that Issa F. Khouri has studied deeply?
Yes, Issa F. Khouri has studied treatments such as Bendamustine, Inotuzumab Ozogamicin, Melphalan.
What is the best way to schedule an appointment with Issa F. Khouri?
Apply for one of the trials that Issa F. Khouri is conducting.
What is the office address of Issa F. Khouri?
The office of Issa F. Khouri is located at: M D Anderson Cancer Center, Houston, Texas 77030 United States. This is the address for their practice at the M D Anderson Cancer Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.