Jimmy Ruiz, MD | Wake Forest University ...

Dr. Jimmy Ruiz

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Wake Forest University Health Sciences

Studies Lung Cancer
Studies Non-Small Cell Lung Cancer
11 reported clinical trials
24 drugs studied

Area of expertise

1

Lung Cancer

Jimmy Ruiz has run 8 trials for Lung Cancer. Some of their research focus areas include:

Stage IV
Stage III
Stage II
2

Non-Small Cell Lung Cancer

Jimmy Ruiz has run 6 trials for Non-Small Cell Lung Cancer. Some of their research focus areas include:

Stage IV
Stage III
PD-L1 positive

Affiliated Hospitals

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Wake Forest University Health Sciences

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Wake Forest University At Clemmons

Clinical Trials Jimmy Ruiz is currently running

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Tazemetostat + Topotecan + Pembrolizumab

for Small Cell Lung Cancer

This phase I trial tests the safety, side effects, and best dose of tazemetostat in combination with topotecan and pembrolizumab in treating patients with small cell lung cancer that has come back after a period of improvement (recurrent). Tazemetostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as topotecan, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving tazemetostat in combination with topotecan and pembrolizumab may shrink or stabilize recurrent small cell lung cancer.

Recruiting

1 award

Phase 1

19 criteria

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Immunotherapy + Chemotherapy

for Non-Small Cell Lung Cancer

This phase III ALCHEMIST treatment trial tests the addition of pembrolizumab to usual chemotherapy for the treatment of stage IIA, IIB, IIIA or IIIB non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs, such as cisplatin, pemetrexed, carboplatin, gemcitabine hydrochloride, and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving pembrolizumab with usual chemotherapy may help increase survival times in patients with stage IIA, IIB, IIIA or IIIB non-small cell lung cancer.

Recruiting

2 awards

Phase 3

27 criteria

More about Jimmy Ruiz

Clinical Trial Related

6 years of experience running clinical trials · Led 11 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Jimmy Ruiz has experience with

  • Pembrolizumab
  • Carboplatin
  • Berzosertib
  • Gemcitabine Hydrochloride
  • Topotecan Hydrochloride
  • Zimberelimab

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