Dr. John P. Mastandrea
Claim this profileUniversity of Maryland Shore Medical Center at Easton
Studies Cancer
Studies Tumors
5 reported clinical trials
24 drugs studied
Area of expertise
1Cancer
Stage IV
Stage I
Stage II
2Tumors
Stage IV
Affiliated Hospitals
Clinical Trials John P. Mastandrea is currently running
Hormone + Radiation Therapy
for Prostate Cancer
This phase III trial compares less intense hormone therapy and radiation therapy to usual hormone therapy and radiation therapy in treating patients with high risk prostate cancer and low gene risk score. This trial also compares more intense hormone therapy and radiation therapy to usual hormone therapy and radiation therapy in patients with high risk prostate cancer and high gene risk score. Apalutamide may help fight prostate cancer by blocking the use of androgen by the tumor cells. Radiation therapy uses high energy rays to kill tumor cells and shrink tumors. Giving a shorter hormone therapy treatment may work the same at controlling prostate cancer compared to the usual 24 month hormone therapy treatment in patients with low gene risk score. Adding apalutamide to the usual treatment may increase the length of time without prostate cancer spreading as compared to the usual treatment in patients with high gene risk score.
Recruiting2 awards Phase 36 criteria
Stereotactic Radiosurgery vs Whole-Brain Radiotherapy
for Brain Metastasis from Lung Cancer
This phase III trial compares the effect of stereotactic radiosurgery to standard of care memantine and whole brain radiation therapy that avoids the hippocampus (the memory zone of the brain) for the treatment of small cell lung cancer that has spread to the brain. Stereotactic radiosurgery is a specialized radiation therapy that delivers a single, high dose of radiation directly to the tumor and may cause less damage to normal tissue. Whole brain radiation therapy delivers a low dose of radiation to the entire brain including the normal brain tissue. Hippocampal avoidance during whole-brain radiation therapy (HA-WBRT) decreases the amount of radiation that is delivered to the hippocampus which is a brain structure that is important for memory. The drug, memantine, is also often given with whole brain radiotherapy because it may decrease the risk of side effects related to thinking and memory. Stereotactic radiosurgery may decrease side effects related to memory and thinking compared to standard of care HA-WBRT plus memantine.
Recruiting2 awards Phase 315 criteria
More about John P. Mastandrea
Clinical Trial Related3 years of experience running clinical trials · Led 5 trials as a Principal Investigator · 5 Active Clinical TrialsTreatments John P. Mastandrea has experience with
- Degarelix
- Histrelin
- Leuprolide
- Buserelin
- Bicalutamide
- Triptorelin
Breakdown of trials John P. Mastandrea has run
Cancer
Tumors
Small Cell Carcinoma
Small Cell Lung Cancer
Other Doctors you might be interested in
Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does John P. Mastandrea specialize in?
John P. Mastandrea focuses on Cancer and Tumors. In particular, much of their work with Cancer has involved Stage IV patients, or patients who are Stage I.
Is John P. Mastandrea currently recruiting for clinical trials?
Yes, John P. Mastandrea is currently recruiting for 5 clinical trials in Easton Maryland. If you're interested in participating, you should apply.
Are there any treatments that John P. Mastandrea has studied deeply?
Yes, John P. Mastandrea has studied treatments such as Degarelix, Histrelin, Leuprolide.
What is the best way to schedule an appointment with John P. Mastandrea?
Apply for one of the trials that John P. Mastandrea is conducting.
What is the office address of John P. Mastandrea?
The office of John P. Mastandrea is located at: University of Maryland Shore Medical Center at Easton, Easton, Maryland 21601 United States. This is the address for their practice at the University of Maryland Shore Medical Center at Easton.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.