Dr. Joseph J. Vadakara
Claim this profileGeisinger Medical Center
About Joseph J. Vadakara
Education:
- Obtained MD from Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, in 1987.
- Completed Residency in Internal Medicine at Geisinger Medical Center, Danville, PA (1987-1990).
- Undertook Fellowship in Cardiovascular Disease at Geisinger Medical Center, Danville, PA (1990-1993).
Experience:
- Currently serves as a Cardiologist and Professor of Medicine at Geisinger Medical Center.
Area of expertise
Acute Myelogenous Leukemia
Joseph J. Vadakara has run 6 trials for Acute Myelogenous Leukemia. Some of their research focus areas include:
Acute Myeloid Leukemia
Joseph J. Vadakara has run 6 trials for Acute Myeloid Leukemia. Some of their research focus areas include:
Affiliated Hospitals
Geisinger Medical Center
Geisinger Wyoming Valley/Henry Cancer Center
Clinical Trials Joseph J. Vadakara is currently running
Venetoclax + HMA
for Acute Myeloid Leukemia
This phase II MyeloMATCH treatment trial compares the usual treatment of azacitidine and venetoclax to the combination treatment of azacitidine, venetoclax and gilteritinib in treating older and unfit patients with acute myeloid leukemia and FLT3 mutations. Azacitidine is a drug that is absorbed into DNA and leads to the activation of cancer suppressor genes, which are genes that help control cell growth. Venetoclax is in a class of medications called B-cell lymphoma-2 (BCL-2) inhibitors. It may stop the growth of cancer cells by blocking Bcl-2, a protein needed for cancer cell survival. Gilteritinib is in a class of medications called kinase inhibitors. It works by blocking the action of a certain naturally occurring substance that may be needed to help cancer cells multiply. This study may help doctors find out if these different approaches are better than the usual approaches. To decide if they are better, the study doctors are looking to see if the study drugs lead to a higher percentage of patients achieving a deeper remission compared to the usual approach.
Recruiting
1 award
Phase 2
7 criteria
Blinatumomab + Chemotherapy
for Leukemia
This phase III trial compares the effect of usual treatment of chemotherapy and steroids and a tyrosine kinase inhibitor (TKI) to the same treatment plus blinatumomab. Blinatumomab is a Bi-specific T-Cell Engager ('BiTE') that may interfere with the ability of cancer cells to grow and spread. The information gained from this study may help researchers determine if combination therapy with steroids, TKIs, and blinatumomab work better than the standard of care.
Recruiting
2 awards
Phase 3
10 criteria
More about Joseph J. Vadakara
Clinical Trial Related
7 years of experience running clinical trials · Led 24 trials as a Principal Investigator · 9 Active Clinical Trials
Treatments Joseph J. Vadakara has experience with
- Cytarabine
- Venetoclax
- Dasatinib
- Pembrolizumab
- Azacitidine
- Lenalidomide
Breakdown of trials Joseph J. Vadakara has run
Acute Myelogenous Leukemia
Acute Myeloid Leukemia
Melanoma
Lymphoma
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Joseph J. Vadakara specialize in?
Joseph J. Vadakara focuses on Acute Myelogenous Leukemia and Acute Myeloid Leukemia. In particular, much of their work with Acute Myelogenous Leukemia has involved FLT3 positive patients, or patients who are PML-RARA negative.
Is Joseph J. Vadakara currently recruiting for clinical trials?
Yes, Joseph J. Vadakara is currently recruiting for 9 clinical trials in Danville Pennsylvania. If you're interested in participating, you should apply.
Are there any treatments that Joseph J. Vadakara has studied deeply?
Yes, Joseph J. Vadakara has studied treatments such as Cytarabine, Venetoclax, Dasatinib.
What is the best way to schedule an appointment with Joseph J. Vadakara?
Apply for one of the trials that Joseph J. Vadakara is conducting.
What is the office address of Joseph J. Vadakara?
The office of Joseph J. Vadakara is located at: Geisinger Medical Center, Danville, Pennsylvania 17822 United States. This is the address for their practice at the Geisinger Medical Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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