Dr. Karen Choong, MD
Claim this profileMcMaster Children's Hospital
Studies Septic Shock
Studies Shock
2 reported clinical trials
3 drugs studied
Affiliated Hospitals
Clinical Trials Karen Choong, MD is currently running
Rapid Vitamin D Supplementation
for Vitamin D Deficiency
Vitamin D plays an important role in calcium balance, heart and lung health, inflammation, infection prevention, and muscle strength. Due to these roles, it has been suggested that critically ill patients with low vitamin D levels might have higher rates of death and worse long-term health. We believe that identifying critically ill children with vitamin D deficiency and then restoring vitamin D levels quickly could represent a safe, easy and inexpensive means of reducing patient illness, preventing death and improving quality of life. This clinical trial will determine whether rapid normalization of vitamin D deficiency improves survival and health-related quality of life following critical illness. The VITdALIZE-KIDS trial is a multicentre randomized clinical trial in Canadian Pediatric Intensive Care Units (PICUs). Critically ill children who agree to participate (consent given by caregivers) will have their blood vitamin D level measured, and those who are vitamin D deficient will be randomized to receive a single dose of either high-dose vitamin D3 or placebo (no drug). Study participants assigned to the high-dose vitamin D arm will receive 10,000 IU/kg of enteral cholecalciferol (up to a maximum of 400,000 IU). We have tested this dose in a pilot trial, and no patient experienced serious adverse events related to vitamin D administration. Patients will be followed for 90 days to determine whether they survived and had a significant change in their health and quality of life. Vitamin D deficiency is a common problem not only among critically ill Canadian children, but in PICUs worldwide. In addition to being applicable in Canada, our study protocol was designed to be generalizable and meaningful to critically ill children worldwide.
Recruiting1 award Phase 3
Hydrocortisone
for Pediatric Septic Shock
SHIPSS is a multi-institutional, prospective, controlled, randomized, double-blinded interventional trial that will examine the potential benefits and risks of adjunctive hydrocortisone prescribed for children with fluid and vasoactive-inotropic refractory septic shock. It is hypothesized that adjunctive hydrocortisone will significantly reduce the incidence of new and progressive organ dysfunction (primary outcome) and proportion of children with poor outcomes, defined as death or severely impaired health-related quality of life (HRQL) (secondary outcome), as assessed at 28 days following study enrollment (randomization).
Recruiting1 award Phase 3
More about Karen Choong, MD
Clinical Trial Related5 years of experience running clinical trials · Led 2 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Karen Choong, MD has experience with
- Hydrocortisone
- Cholecalciferol
- Placebo
Breakdown of trials Karen Choong, MD has run
Septic Shock
Vitamin D Deficiency
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Karen Choong, MD specialize in?
Karen Choong, MD focuses on Septic Shock and Shock. In particular, much of their work with Septic Shock has involved treating patients, or patients who are undergoing treatment.
Is Karen Choong, MD currently recruiting for clinical trials?
Yes, Karen Choong, MD is currently recruiting for 2 clinical trials in Hamilton Ontario. If you're interested in participating, you should apply.
Are there any treatments that Karen Choong, MD has studied deeply?
Yes, Karen Choong, MD has studied treatments such as Hydrocortisone, Cholecalciferol, Placebo.
What is the best way to schedule an appointment with Karen Choong, MD?
Apply for one of the trials that Karen Choong, MD is conducting.
What is the office address of Karen Choong, MD?
The office of Karen Choong, MD is located at: McMaster Children's Hospital, Hamilton, Ontario L8N 3Z5 Canada. This is the address for their practice at the McMaster Children's Hospital.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.