Dr. Laurent Macle, MD
Claim this profileMontreal Heart Institute
Studies Atrial Fibrillation
Studies Emergency
2 reported clinical trials
3 drugs studied
Affiliated Hospitals
Clinical Trials Laurent Macle, MD is currently running
Ablation
for Atrial Fibrillation
A multicentre, parallel group, two arm, single-blinded randomized clinical trial, assessing the efficacy of a patient-tailored catheter ablation (CA) strategy guided by atrial scar mapping in addition to pulmonary vein isolation (PVI) when compared to PVI alone in patients with persistent atrial fibrillation (AF).
Recruiting1 award N/A5 criteria
Vernakalant vs. Procainamide
for Atrial Fibrillation
The objective is to compare IV vernakalant to IV procainamide for the ED management of acute AF patients. If vernakalant proves to be more effective, faster, and safer than IV procainamide, this will give clinicians an important alternative for pharmacological cardioversion of acute AF. The investigators propose a pragmatic comparative effectiveness trial entailing an open label, randomized controlled trial at 12 large Canadian EDs. Study subjects will be randomized to 1 of 2 treatment arms: 1) Patients will receive an initial infusion of 3mg/kg of IV vernakalant over 10 minutes, followed by a second dose of 2mg/kg over 10 minutes, if necessary, or 2) Patients will receive a continuous infusion of 15mg/kg of IV procainamide over 60 minutes. The primary aim will be to compare conversion to normal sinus rhythm between the two drugs. The investigators will include stable patients presenting with an episode of acute AF of at least 3 hours duration, where symptoms require urgent management and where immediate cardioversion is a reasonable option. Using the integrated consent model, research assistants will obtain verbal consent from eligible patients.
Recruiting3 awards Phase 44 criteria
More about Laurent Macle, MD
Clinical Trial Related6 years of experience running clinical trials · Led 2 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Laurent Macle, MD has experience with
- Catheter Ablation
- Procainamide
- Vernakalant
Breakdown of trials Laurent Macle, MD has run
Atrial Fibrillation
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Laurent Macle, MD specialize in?
Laurent Macle, MD focuses on Atrial Fibrillation and Emergency. In particular, much of their work with Atrial Fibrillation has involved treating patients, or patients who are undergoing treatment.
Is Laurent Macle, MD currently recruiting for clinical trials?
Yes, Laurent Macle, MD is currently recruiting for 2 clinical trials in Montreal Quebec. If you're interested in participating, you should apply.
Are there any treatments that Laurent Macle, MD has studied deeply?
Yes, Laurent Macle, MD has studied treatments such as Catheter ablation, Procainamide, Vernakalant.
What is the best way to schedule an appointment with Laurent Macle, MD?
Apply for one of the trials that Laurent Macle, MD is conducting.
What is the office address of Laurent Macle, MD?
The office of Laurent Macle, MD is located at: Montreal Heart Institute, Montreal, Quebec H1T 1C8 Canada. This is the address for their practice at the Montreal Heart Institute.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.