Dr. Lori Davis, MD

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Tuscaloosa VA Medical Center, Tuscaloosa, AL

Studies Post-Traumatic Stress Disorder
Studies Opioid Dependence
2 reported clinical trials
4 drugs studied

Affiliated Hospitals

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Tuscaloosa VA Medical Center, Tuscaloosa, AL

Clinical Trials Lori Davis, MD is currently running

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Methylphenidate

for Post-Traumatic Stress Disorder

Posttraumatic stress disorder (PTSD) is frequently accompanied by difficulty concentrating, poor memory, and inability to keep up with tasks, which negatively impacts a person's ability to function at work and in relationships. Currently available treatments do not fully relieve all symptoms. A published research report showed positive evidence that the stimulant medication methylphenidate was beneficial in treating these problems. This study will evaluate the ability of methylphenidate to treat PTSD and associated neurocognitive complaints in Veterans. An innovative feature is the study's N-of-1 design. In this design, every participant will move back and forth every 4-5 weeks between treatment with methylphenidate and treatment with placebo, in random order and under double-blind conditions, over a 20-week period. The investigators will compare the aggregated change in PTSD and neurocognitive symptoms between periods of treatment with methylphenidate versus placebo. Results will help clinicians to better choose the best treatment for Veterans living with PTSD.
Recruiting2 awards Phase 4
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Buprenorphine Forms

for Opioid Use Disorder

VA-BRAVE will determine whether a 28-day long-acting injectable sub-cutaneous (in the belly area) formulation of buprenorphine at a target dose of 300mg is superior in retaining Veterans in opioid treatment and in sustaining opioid abstinence compared to the daily sublingual (under the tongue) buprenorphine formulation at a target dose of 16-32 mg (standard of care). This is an open-label, randomized, controlled trial including 952 Veterans with opioid use disorder (OUD) recruited over 7 years and followed actively for 52 weeks. There are a number of secondary objectives that will be studied as well and include: comorbid substance use, both non-fatal and fatal opioid overdose, HIV and Hepatitis B (HBV) and C (HCV) testing results and risk behaviors, incarceration, quality of life, psychiatric symptoms of depression and posttraumatic stress disorder, housing status, dental health and utilization, and cost-effectiveness.
Recruiting3 awards Phase 43 criteria

More about Lori Davis, MD

Clinical Trial Related1 year of experience running clinical trials · Led 2 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Lori Davis, MD has experience with
  • Methylphenidate
  • Placebo
  • Injectable Subcutaneous Buprenorphine
  • Sublingual Buprenorphine With Naloxone
Breakdown of trials Lori Davis, MD has run

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Frequently asked questions

Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Lori Davis, MD specialize in?
Lori Davis, MD focuses on Post-Traumatic Stress Disorder and Opioid Dependence. In particular, much of their work with Post-Traumatic Stress Disorder has involved treating patients, or patients who are undergoing treatment.
Is Lori Davis, MD currently recruiting for clinical trials?
Yes, Lori Davis, MD is currently recruiting for 2 clinical trials in Tuscaloosa Alabama. If you're interested in participating, you should apply.
Are there any treatments that Lori Davis, MD has studied deeply?
Yes, Lori Davis, MD has studied treatments such as Methylphenidate, Placebo, Injectable subcutaneous buprenorphine.
What is the best way to schedule an appointment with Lori Davis, MD?
Apply for one of the trials that Lori Davis, MD is conducting.
What is the office address of Lori Davis, MD?
The office of Lori Davis, MD is located at: Tuscaloosa VA Medical Center, Tuscaloosa, AL, Tuscaloosa, Alabama 35404-5015 United States. This is the address for their practice at the Tuscaloosa VA Medical Center, Tuscaloosa, AL.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.