Mark F. Kozloff, MD - UChicago Medicine

Dr. Mark F. Kozloff

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Ingalls Memorial Hospital

Studies Breast cancer
Studies Colorectal Cancer
26 reported clinical trials
77 drugs studied

About Mark F. Kozloff

Education:

  • Obtained a Medical degree (MD) from Rush Medical College, Chicago, IL.
  • Completed Residency in Internal Medicine at the University of Chicago Hospitals.
  • Undertook a Fellowship in Infectious Diseases at the University of Chicago Hospitals.

Experience:

  • Currently serves as the Chief of Infectious Diseases at Ingalls Memorial Hospital.
  • Holds the position of Associate Professor of Medicine at the University of Chicago Pritzker School of Medicine.

Area of expertise

1

Breast Cancer

Mark F. Kozloff has run 6 trials for Breast cancer. Some of their research focus areas include:

Stage IV
Stage III
PD-L1 positive
2

Colorectal Cancer

Mark F. Kozloff has run 5 trials for Colorectal Cancer. Some of their research focus areas include:

Stage III
Stage IV
Stage II

Affiliated Hospitals

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Ingalls Memorial Hospital

Clinical Trials Mark F. Kozloff is currently running

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Chemotherapy + Immunotherapy

for Esophageal and Gastric Cancer

This phase III trial compares the effect of modified fluorouracil, leucovorin calcium, oxaliplatin, and irinotecan (mFOLFIRINOX) to modified fluorouracil, leucovorin calcium, and oxaliplatin (mFOLFOX) for the treatment of advanced, unresectable, or metastatic HER2 negative esophageal, gastroesophageal junction, and gastric adenocarcinoma. The usual approach for patients is treatment with FOLFOX chemotherapy. Chemotherapy drugs work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Fluorouracil stops cells from making DNA and it may kill tumor cells. Leucovorin is used with fluorouracil to enhance the effects of the drug. Oxaliplatin works by killing, stopping, or slowing the growth of tumor cells. Some patients also receive an immunotherapy drug, nivolumab, in addition to FOLFOX chemotherapy. Immunotherapy may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Irinotecan blocks certain enzymes needed for cell division and DNA repair, and it may kill tumor cells. Adding irinotecan to the FOLFOX regimen could shrink the cancer and extend the life of patients with advanced gastroesophageal cancers.

Recruiting

2 awards

Phase 3

2 criteria

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Atezolizumab + Chemotherapy

for Neuroendocrine Carcinoma

This trial is testing a new treatment combining an immune-boosting drug with standard chemotherapy for patients with a specific type of aggressive cancer that has spread. The goal is to help the immune system fight the cancer and use chemotherapy to kill cancer cells.

Recruiting

1 award

Phase 2 & 3

10 criteria

More about Mark F. Kozloff

Clinical Trial Related

7 years of experience running clinical trials · Led 26 trials as a Principal Investigator · 4 Active Clinical Trials

Treatments Mark F. Kozloff has experience with

  • Atezolizumab
  • Fluorouracil
  • Carboplatin
  • Nivolumab
  • Irinotecan
  • Leucovorin Calcium

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