Dr. Mary Cunningham, M.D.
Claim this profileState University of New York Upstate Medical University
Studies Ovarian Cancer
Studies Cancer
14 reported clinical trials
46 drugs studied
Area of expertise
1Ovarian Cancer
Stage IV
BRCA1 positive
Stage III
2Cancer
Stage IV
Stage III
BRCA1 positive
Affiliated Hospitals
Clinical Trials Mary Cunningham, M.D. is currently running
Selumetinib + Olaparib
for Ovarian and Endometrial Cancer
This phase II ComboMATCH treatment trial compares selumetinib plus olaparib to selumetinib alone in women with endometrial or ovarian (fallopian tube and primary peritoneal) cancer that has come back (recurrent) or that remains despite treatment (persistent) and harbors a mutation in the RAS pathway. Selumetinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Olaparib is an inhibitor of PARP, an enzyme that helps repair deoxyribonucleic acid (DNA) when it becomes damaged. Blocking PARP may help keep tumor cells from repairing their damaged DNA, causing them to die. PARP inhibitors are a type of targeted therapy. The addition of olaparib to selumetinib could increase the percentage of tumors that shrink as well as lengthen the time that the tumors remain stable (without progression) as compared to selumetinib alone.
Recruiting1 award Phase 2
Letrozole +/- Chemotherapy
for Ovarian Cancer
This phase III trial studies how well letrozole with or without paclitaxel and carboplatin works in treating patients with stage II-IV low-grade serous carcinoma of the ovary, fallopian tube, or peritoneum. Letrozole is an enzyme inhibitor that lowers the amount of estrogen made by the body which in turn may stop the growth of tumor cells that need estrogen to grow. Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known whether giving letrozole alone or in combination with paclitaxel and carboplatin works better in treating patients with low-grade serous carcinoma of the ovary, fallopian tube, or peritoneum compared to paclitaxel and carboplatin without letrozole.
Recruiting2 awards Phase 318 criteria
More about Mary Cunningham, M.D.
Clinical Trial Related1 year of experience running clinical trials · Led 14 trials as a Principal Investigator · 7 Active Clinical TrialsTreatments Mary Cunningham, M.D. has experience with
- Paclitaxel
- Olaparib
- Letrozole
- Carboplatin
- Selumetinib Sulfate
- Palbociclib
Breakdown of trials Mary Cunningham, M.D. has run
Ovarian Cancer
Cancer
Recurrence
Fallopian Tube Cancer
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Mary Cunningham, M.D. specialize in?
Mary Cunningham, M.D. focuses on Ovarian Cancer and Cancer. In particular, much of their work with Ovarian Cancer has involved Stage IV patients, or patients who are BRCA1 positive.
Is Mary Cunningham, M.D. currently recruiting for clinical trials?
Yes, Mary Cunningham, M.D. is currently recruiting for 7 clinical trials in Syracuse New York. If you're interested in participating, you should apply.
Are there any treatments that Mary Cunningham, M.D. has studied deeply?
Yes, Mary Cunningham, M.D. has studied treatments such as Paclitaxel, Olaparib, Letrozole.
What is the best way to schedule an appointment with Mary Cunningham, M.D.?
Apply for one of the trials that Mary Cunningham, M.D. is conducting.
What is the office address of Mary Cunningham, M.D.?
The office of Mary Cunningham, M.D. is located at: State University of New York Upstate Medical University, Syracuse, New York 13210 United States. This is the address for their practice at the State University of New York Upstate Medical University.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.