Dr. Neal E. Dunlap
Claim this profileThe James Graham Brown Cancer Center at University of Louisville
Studies Cancer
Studies Squamous Cell Carcinoma
15 reported clinical trials
36 drugs studied
Area of expertise
1Cancer
p16 negative
Stage II
Stage I
2Squamous Cell Carcinoma
p16 negative
Stage II
Stage I
Affiliated Hospitals
Clinical Trials Neal E. Dunlap is currently running
Pembrolizumab + Radiation vs Chemotherapy + Radiation
for Head and Neck Cancer
This phase II trial studies the effect of pembrolizumab alone compared to the usual approach (chemotherapy \[cisplatin and carboplatin\] plus radiation therapy) after surgery in treating patients with head and neck squamous cell carcinoma that has come back (recurrent) or patients with a second head and neck cancer that is not from metastasis (primary). Radiation therapy uses high energy radiation or protons to kill tumor cells and shrink tumors. Cisplatin is in a class of medications known as platinum-containing compounds. It works by killing, stopping or slowing the growth of cancer cells. Carboplatin is also in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of cancer cells. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer and may interfere with the ability of tumor cells to grow and spread. Giving pembrolizumab alone after surgery may work better than the usual approach in shrinking recurrent or primary head and neck squamous cell carcinoma.
Recruiting1 award Phase 231 criteria
Chemotherapy + Radiation Therapy
for Head and Neck Cancer
This phase II/III trial studies how well radiation therapy works when given together with cisplatin, docetaxel, cetuximab, and/or atezolizumab after surgery in treating patients with high-risk stage III-IV head and neck cancer the begins in the thin, flat cells (squamous cell). Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. Drugs used in chemotherapy, such as cisplatin and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Cetuximab is a monoclonal antibody that may interfere with the ability of tumor cells to grow and spread. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. The purpose of this study is to compare the usual treatment (radiation therapy with cisplatin chemotherapy) to using radiation therapy with docetaxel and cetuximab chemotherapy, and using the usual treatment plus an immunotherapy drug, atezolizumab.
Recruiting1 award Phase 2 & 321 criteria
More about Neal E. Dunlap
Clinical Trial Related3 years of experience running clinical trials · Led 15 trials as a Principal Investigator · 9 Active Clinical TrialsTreatments Neal E. Dunlap has experience with
- Cisplatin
- Intensity-Modulated Radiation Therapy
- Docetaxel
- Carboplatin
- Atezolizumab
- Pembrolizumab
Breakdown of trials Neal E. Dunlap has run
Cancer
Squamous Cell Carcinoma
Lung Cancer
Small Cell Lung Cancer
Other Doctors you might be interested in
Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Neal E. Dunlap specialize in?
Neal E. Dunlap focuses on Cancer and Squamous Cell Carcinoma. In particular, much of their work with Cancer has involved p16 negative patients, or patients who are Stage II.
Is Neal E. Dunlap currently recruiting for clinical trials?
Yes, Neal E. Dunlap is currently recruiting for 9 clinical trials in Louisville Kentucky. If you're interested in participating, you should apply.
Are there any treatments that Neal E. Dunlap has studied deeply?
Yes, Neal E. Dunlap has studied treatments such as Cisplatin, Intensity-Modulated Radiation Therapy, Docetaxel.
What is the best way to schedule an appointment with Neal E. Dunlap?
Apply for one of the trials that Neal E. Dunlap is conducting.
What is the office address of Neal E. Dunlap?
The office of Neal E. Dunlap is located at: The James Graham Brown Cancer Center at University of Louisville, Louisville, Kentucky 40202 United States. This is the address for their practice at the The James Graham Brown Cancer Center at University of Louisville.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.