Dr. Pamela J McShane, MD
Claim this profileUniversity of Texas Health Science Center
Studies Tuberculosis
Studies Bronchiectasis
5 reported clinical trials
8 drugs studied
Affiliated Hospitals
University Of Texas Health Science Center
University Of Texas Health Science Center At Tyler
Clinical Trials Pamela J McShane, MD is currently running
Antibiotic Therapy
for Mycobacterium Avium Complex Infection
NTM therapy consists of a multi-drug macrolide based regimen for 18-24 months. Treated patients frequently experience debilitating side effects, and many patients delay the start of antibiotic treatment due to these risks. Common side effects include nausea, diarrhea, and fatigue, and rare but serious toxicities include ocular toxicity, hearing loss, and hematologic toxicity. To date, most of the evidence underlying the current treatment recommendations has come from observational studies in which either a macrolide has been combined with rifampin and ethambutol, or in some cases combined with ethambutol alone. The proposed study will answer whether a third drug is necessary or whether taking two drugs can increase tolerability without a substantial loss of efficacy.
Recruiting1 award Phase 2 & 33 criteria
Omadacycline
for Nontuberculous Mycobacterial Lung Disease
This trial is testing an antibiotic called omadacycline to treat adults with a specific lung infection. The antibiotic works by stopping the bacteria from growing. Participants will take the treatment for several months. Omadacycline is a once-daily oral antibiotic approved in the United States for the treatment of certain bacterial infections in adults.
Recruiting0 awards Phase 24 criteria
More about Pamela J McShane, MD
Clinical Trial Related5 years of experience running clinical trials · Led 5 trials as a Principal Investigator · 3 Active Clinical TrialsTreatments Pamela J McShane, MD has experience with
- Placebo
- AP-PA02
- Omadacycline
- ARINA-1
- Clofazimine
- Azithromycin
Breakdown of trials Pamela J McShane, MD has run
Tuberculosis
Contagious Diseases
Infections
Nontuberculous Mycobacterial Infections
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Pamela J McShane, MD specialize in?
Pamela J McShane, MD focuses on Tuberculosis and Bronchiectasis. In particular, much of their work with Tuberculosis has involved treating patients, or patients who are undergoing treatment.
Is Pamela J McShane, MD currently recruiting for clinical trials?
Yes, Pamela J McShane, MD is currently recruiting for 3 clinical trials in Tyler Texas. If you're interested in participating, you should apply.
Are there any treatments that Pamela J McShane, MD has studied deeply?
Yes, Pamela J McShane, MD has studied treatments such as Placebo, AP-PA02, Omadacycline.
What is the best way to schedule an appointment with Pamela J McShane, MD?
Apply for one of the trials that Pamela J McShane, MD is conducting.
What is the office address of Pamela J McShane, MD?
The office of Pamela J McShane, MD is located at: University of Texas Health Science Center, Tyler, Texas 75708 United States. This is the address for their practice at the University of Texas Health Science Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.