Patrick A. Flume MD | MUSC Charleston, SC

Dr. Patrick A Flume, MD

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Medical University of South Carolina

Studies Cystic Fibrosis
Studies Bronchiectasis
13 reported clinical trials
15 drugs studied

Affiliated Hospitals

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Medical University Of South Carolina
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Medical University Of South Carolina MUSC

Clinical Trials Patrick A Flume, MD is currently running

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Parenthood Impact on Health

for Cystic Fibrosis

The goal of this observational prospective study is to determine the health impact of parenthood on United States (US) people with CF in the era of CF transmembrane regulator protein (CFTR) modulators. The investigators will collect physical and mental health data to comprehensively evaluate the impact of parenthood in CF with widespread highly effective CFTR modulator use. The main hypotheses this study aims to examine are: H1: Parents with CF and moderate-to-severe depression have more rapid change in ppFEV1 (percent predicted forced expiratory volume in one second) versus those with mild or no depression. H2: Parents with CF who have more parental responsibility and/or stress have more rapid ppFEV1 (percent predicted forced expiratory volume in one second) change than those with less responsibility/stress H3: Parents using CFTR modulators have decreased ppFEV1 (percent predicted forced expiratory volume in one second) change versus those not using CFTR modulators Participants will complete quarterly surveys during the first year of parenthood and biannual surveys, thereafter, using the computer-based survey system on an iPad protected for infection control or via personal device or computer via emailed survey link.
Recruiting1 award N/A2 criteria
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Antibiotics

for Cystic Fibrosis Pulmonary Exacerbations

This trial is testing whether using one antibiotic or two different antibiotics together is better for treating lung infections in people with cystic fibrosis. It targets patients with worsening lung symptoms needing IV antibiotics. The antibiotics work by killing or stopping bacteria to improve breathing and reduce symptoms.
Recruiting3 awards Phase 44 criteria

More about Patrick A Flume, MD

Clinical Trial Related1 year of experience running clinical trials · Led 13 trials as a Principal Investigator · 3 Active Clinical Trials
Treatments Patrick A Flume, MD has experience with
  • Placebo
  • AP-PA02
  • Aminoglycoside
  • Beta-lactam Antibiotic
  • ARINA-1
  • Sodium Fusidate

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