Dr. Dr. Paul Thornton
Claim this profileCook Children's Medical Center
Studies Hyperinsulinemic Hypoglycemia
Studies Hyperinsulinism
9 reported clinical trials
10 drugs studied
Area of expertise
1Hyperinsulinemic Hypoglycemia
KCNJ11 negative
ABCC8 negative
2Hyperinsulinism
KCNJ11 negative
ABCC8 negative
Affiliated Hospitals
Clinical Trials Dr. Paul Thornton is currently running
Fluorodopa F 18
for Congenital Hyperinsulinism
Low blood sugars are known to cause brain damage in newborn babies. One of the most common causes of low blood sugars persisting beyond the new born period is a condition called congenital hyperinsulinism (HI). This is a disease whereby the pancreas secretes too much insulin and causes low blood sugars. Twenty to forty percent of these babies will have brain damage. There are two forms of this disease. In one form only a small part of the pancreas makes too much insulin (focal HI) and in the other, the whole pancreas make too much insulin (diffuse HI). Another very similar disease is insulinoma which occurs after birth, but also causes hyperinsulinism. If a surgeon could know which part of the pancreas has the focal lesion he could remove it and cure the patient. The purpose of this study is to investigate whether a new investigational drug called Fluorodopa F 18, when used with a PET scan, can find the focal lesion and guide the surgeon to remove it, thus curing the patient and preventing further brain damage.
Recruiting1 award Phase 13 criteria
Dasiglucagon
for Low Blood Sugar
This research study will investigate whether dasiglucagon as a rescue therapy for participants under 6 years of age works and is safe to use. In addition, the study will investigate how dasiglucagon works in the body (pharmacokinetics and pharmacodynamics). Participants will receive 1 single dose as an injection under the skin (subcutaneous, s.c.) into the buttocks. Participants will have 3 visits with the study team. For each participant, the study will last up to 84 days.
Recruiting2 awards Phase 33 criteria
More about Dr. Paul Thornton
Clinical Trial Related4 years of experience running clinical trials · Led 9 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Dr. Paul Thornton has experience with
- Fluorodopa F 18
- Somatropin
- RZ358
- LUM-201
- Tildacerfont
- GenSci004
Breakdown of trials Dr. Paul Thornton has run
Hyperinsulinemic Hypoglycemia
Hyperinsulinism
Nesidioblastosis
Congenital Hyperinsulinism
Other Doctors you might be interested in
Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Dr. Paul Thornton specialize in?
Dr. Paul Thornton focuses on Hyperinsulinemic Hypoglycemia and Hyperinsulinism. In particular, much of their work with Hyperinsulinemic Hypoglycemia has involved KCNJ11 negative patients, or patients who are ABCC8 negative.
Is Dr. Paul Thornton currently recruiting for clinical trials?
Yes, Dr. Paul Thornton is currently recruiting for 2 clinical trials in Fort Worth Texas. If you're interested in participating, you should apply.
Are there any treatments that Dr. Paul Thornton has studied deeply?
Yes, Dr. Paul Thornton has studied treatments such as Fluorodopa F 18, Somatropin, RZ358.
What is the best way to schedule an appointment with Dr. Paul Thornton?
Apply for one of the trials that Dr. Paul Thornton is conducting.
What is the office address of Dr. Paul Thornton?
The office of Dr. Paul Thornton is located at: Cook Children's Medical Center, Fort Worth, Texas 76104 United States. This is the address for their practice at the Cook Children's Medical Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.